Hydrogen Bonded Helical Configurations of the Polypeptide Chain.

the Massachusetts Institute of Technology and from the U. S. Public Health Service to the Massachusetts General Hospital. t This is publication No. 141 of the Robert W. Lovett Memorial Foundation for the Study of Crippling Disease, Department of Medicine, Massachusetts General Hospital and Harvard Medical School. 1 Schmitt, F. O., Hall, C. E., and Jakus, M. A., J. Cell Comp. Physiol., 20, 11-33 (1942). 2 Bahr, G., Exptl. Cell Research, 1, 603-606 (1950). 3 Vanamee, P., and Porter, K. R., J. Exptl. Med., 94, 255-268 (1951). 4 Noda, H., and Wyckoff, R. W. G., Biochem. et Biophys. Acta., 7, 494-506 (1951). 6 Gross, J., Proc. Josiah Macy Jr. Foundation; Conference on Metabolic Interrelationships, 4, 32-57 (1952). 6 Nageotte, J., and Guyon, L., Arch. Biol., 41, 1-35 (1930). Faure-Fremiet and Garrault, H., Arch. Anal. mic., 33, 81-94 (1937). 8 Highberger, J. H., Gross, J., and Schmitt, F. O., PROC. NATL. ACAD. Sex., 37, 286291 (1951). 9 Tustanovsky, A. A., Biokhimiya, 12, 285-290 (1947). 10 Orekhovich, V. N., Tustanovsky, A. A., Orekhovich, K. D., and Plotnikova, N. E., Biochemiya, 13, 55-60 (1948). 11 Highberger, J. H., Gross, J., and Schmitt, F. O., J. Am. Chem. Soc., 72, 3321 (1950). 12 Gross, J., Highberger, J. H., and Schmitt, F. O., Proc. Soc. Exptl. Biol. Med., 80, 462-465 (1952). 13 It should be noted, however, that a wide variety of proteins and other high polymers will not reproduce this phenomenon. 14 Bresler, C. E., Finogenov, P. A., and Frenkel, S. Y., Repts. Acad. Sci. U.S.S.R., Moscow, 72, 555-558 (1950). Bear, R. S., Adv. Protein Chem., 7, 69-160 (1952). 16 Williams, R. C., Biochem. et Biophys. Acta, 9, 237-239 (1952). 17 Bailey, K., "The Muscle. A Study in Biology and Pathology," L'Expansion Sci. Francaise, 31-46 (1950). 18 Weber, H. H., Adv. Protein Chem., 7, 161-252 (1952). 19 Hodge, A. J., PRoc. NATL. ACAD. SCI., 38, 850-855 (1952). '0 Mercer, E. H., and Olofsson, B., J. Polymer Sci., 6, 671-680 (1951).