Rapid prototyping of orthopedic implant materials for cranio-facial reconstruction: A Survey

Abstract Rapid prototyping is swiftly gaining acceptance in the healthcare sector as it is helping surgeons to create patient specific implants in a fraction of time as compared to traditional approaches like injection molding or Computer Numerical Control (CNC) machining. The inputs provided by Surgeons have a major role in designing the implant that is better fit for the patient. It includes usage of techniques such as Three-Dimensional (3D) printing to create patient specific implants made of biologically compatible polymers like Polyether Ether Ketone (PEEK), Polymethyl Methacrylate (PMMA), that replace traditional materials like Steel, Hydroxyapatite (HA) ceramics and Titanium. Polymers like PEEK have shown better bio compatibility and stability when used for implants as compared to traditional materials but lack in osseointegration due to their bio-inert nature. In this study we have surveyed materials such as PEEK, PMMA for Rapid prototyping or 3D Printing of orthopedic implants which are used in craniofacial reconstruction surgery. The outcome of this study may help researchers and surgeons in designing better implants for patients.

[1]  Philipp Honigmann,et al.  Patient-Specific Surgical Implants Made of 3D Printed PEEK: Material, Technology, and Scope of Surgical Application , 2018, BioMed research international.

[2]  S. Ramakrishna,et al.  3D printing of polyether-ether-ketone for biomedical applications , 2019, European Polymer Journal.

[3]  Vicente Chulvi,et al.  Automated design of customized implants , 2013 .

[4]  Aatman Shah,et al.  Materials used in cranioplasty: a history and analysis. , 2014, Neurosurgical focus.

[5]  Shoufeng Yang,et al.  Extrusion-based additive manufacturing of PEEK for biomedical applications , 2015 .

[6]  A. Farman,et al.  Clinical applications of cone-beam computed tomography in dental practice. , 2006, Journal.

[7]  G Fabry,et al.  An overview of implant materials. , 1991, Acta orthopaedica Belgica.

[8]  Amir A. Zadpoor,et al.  Design for Additive Bio-Manufacturing: From Patient-Specific Medical Devices to Rationally Designed Meta-Biomaterials , 2017, International journal of molecular sciences.

[9]  Mohd Javaid,et al.  Polyether ether ketone (PEEK) and its manufacturing of customised 3D printed dentistry parts using additive manufacturing , 2019, Clinical Epidemiology and Global Health.

[10]  Mohd Javaid,et al.  Three-Dimensional-Printed Polyether Ether Ketone Implants for Orthopedics , 2019, Indian journal of orthopaedics.

[11]  M. Robiony,et al.  Cranioplasty: Review of Materials , 2016, The Journal of craniofacial surgery.

[12]  V. Sikavitsas,et al.  Mechanical and in Vitro Investigation of a Porous PEEK Foam for Medical Device Implants , 2013, Journal of applied biomaterials & functional materials.

[13]  Mohd Javaid,et al.  Polyether ether ketone (PEEK) and its 3D printed implants applications in medical field: An overview , 2019, Clinical Epidemiology and Global Health.

[14]  H. Iwamuro,et al.  Analyses of the factors influencing bone graft infection after delayed cranioplasty , 2006, Acta Neurochirurgica.

[15]  Martin Leary,et al.  Just-in-time Design and Additive Manufacture of Patient-specific Medical Implants , 2016 .

[16]  W. Yuan,et al.  Comparison of titanium and polyetheretherketone (PEEK) cages in the surgical treatment of multilevel cervical spondylotic myelopathy: a prospective, randomized, control study with over 7-year follow-up , 2013, European Spine Journal.

[17]  I. Zaed,et al.  Comparison between the different types of heterologous materials used in cranioplasty: a systematic review of the literature. , 2019, Journal of neurosurgical sciences.

[18]  Jeffrey W Stansbury,et al.  3D printing with polymers: Challenges among expanding options and opportunities. , 2016, Dental materials : official publication of the Academy of Dental Materials.

[19]  D. Hukins,et al.  A Review of the Design Process for Implantable Orthopedic Medical Devices , 2009, The open biomedical engineering journal.