Antibiotic treatment of pelvic inflammatory disease. Trends among private physicians in the United States, 1966 through 1983.

Although pelvic inflammatory disease is the most common serious infection among young women of reproductive age in the United States, no nationwide data are available on the patterns of antibiotic treatment of this disease. To examine these patterns we analyzed over 25 million antibiotic prescriptions for treatment of pelvic inflammatory disease from 1966 through 1983, using the National Disease and Therapeutic Index. Most patients received a single antibiotic on an outpatient basis. Overall, use of natural penicillins declined markedly, and use of aminopenicillins more than doubled. Cephalosporins emerged as the most frequently prescribed antibiotic for hospitalized patients. Nationwide surveillance of treatment patterns may help to identify areas needing improvement through continuing education.

[1]  W. Cates,et al.  Self-reported pelvic inflammatory disease in the US: a common occurrence. , 1985, American journal of public health.

[2]  R. Sweet,et al.  High failure rates in outpatient treatment of salpingitis with either tetracycline alone or penicillin/ampicillin combination. , 1985, American journal of obstetrics and gynecology.

[3]  A. Washington,et al.  Pelvic inflammatory disease and its sequelae in adolescents. , 1985, Journal of adolescent health care : official publication of the Society for Adolescent Medicine.

[4]  A. Washington,et al.  Hospitalizations for pelvic inflammatory disease. Epidemiology and trends in the United States, 1975 to 1981. , 1984, JAMA.

[5]  R. Brunham.  Therapy for acute pelvic inflammatory disease: a critique of recent treatment trials. , 1984, American journal of obstetrics and gynecology.

[6]  D. Eschenbach.  Acute pelvic inflammatory disease. , 1984, The Urologic clinics of North America.

[7]  R. Sweet,et al.  Failure of beta-lactam antibiotics to eradicate Chlamydia trachomatis in the endometrium despite apparent clinical cure of acute salpingitis. , 1983, JAMA.

[8]  W. Schaffner,et al.  Improving antibiotic prescribing in office practice. A controlled trial of three educational methods. , 1983, JAMA.

[9]  J. Goodrich.  Pelvic Inflammatory Disease: Considerations Related to Therapy , 1982 .

[10]  B. Skipper,et al.  Physician behavior modification using claims data: tetracycline for upper respiratory infection. , 1982, The Western journal of medicine.

[11]  D. Grimes.  NONGONOCOCCAL PELVIC INFLAMMATORY DISEASE , 1981, Clinical obstetrics and gynecology.

[12]  T. A. Bell,et al.  Computer-assisted analysis of the therapy of acute salpingitis. , 1980, American journal of obstetrics and gynecology.

[13]  K. Wong,et al.  The microbiology and therapy of acute pelvic inflammatory disease in hospitalized patients. , 1980, American journal of obstetrics and gynecology.

[14]  J. Curran.  Management of Gonococcal Pelvic Inflammatory Disease , 1979, Sexually transmitted diseases.

[15]  S. Welkos,et al.  Cul-de-sac isolates from patients with endometritis-salpingitis-peritonitis and gonococcal endocervicitis. , 1976, American journal of obstetrics and gynecology.

[16]  K. Holmes,et al.  Polymicrobial etiology of acute pelvic inflammatory disease. , 1975, The New England journal of medicine.

[17]  L. Jacobson,et al.  Objectivized diagnosis of acute pelvic inflammatory disease. , 1969 .