An approach to quantum gravity and cosmology is proposed based on a synthesis of four elements: 1) the Bekenstein bound and the related holographic hypothesis of 't Hooft and Susskind, 2) topological quantum field theory, 3) a new approach to the interpretational issues of quantum cosmology and 4) the loop representation formulation of non-perturbative quantum gravity. A set of postulates are described, which define a (\it pluralistic quantum cosmological theory.) These incorporates a statistical and relational approach to the interpretation problem, following proposals of Crane and Rovelli, in which there is a Hilbert space associated to each timelike boundary, dividing the universe into two parts. A quantum state of the universe is an assignment of a statistical state into each of these Hilbert spaces, subject to certain conditions of consistency which come from an analysis of the measurement problem. A proposal for a concrete realization of these postulates is described, which is based on certain results in the loop representation and topological quantum field theory, and in particular on the fact that spin networks and punctured surfaces appear in both contexts. The Capovilla-Dell-Jacobson solution of the constraints of quantum gravity are expressed quantum mechanically in the language of Chern-Simons theory, in a way that leads also to the satisfaction of the Bekenstein bound.
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