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The dihydrofolate reductase amplicons in different methotrexate-resistant Chinese hamster cell lines share at least a 273-kilobase core sequence, but the amplicons in some cell lines are much larger and are remarkably uniform in structure
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J. Hamlin
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W. Flintoff
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T. Leu
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J. Looney
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C. Ma
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W. B. Troutman
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C. Ma
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