Single cell metabolic imaging of tumor and immune cells in vivo in melanoma bearing mice
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Amy K. Erbe | M. Skala | P. Sondel | A. Erbe | A. Hoefges | Peter R Rehani | A. Heaton | Angelica F. Lopez
[1] M. Ishii,et al. Multiphoton intravital microscopy of rodents , 2022, Nature Reviews Methods Primers.
[2] E. Shirshin,et al. Label-free imaging of M1 and M2 macrophage phenotypes in the human dermis in vivo using two-photon excited FLIM , 2022, eLife.
[3] A. A. Plekhanov,et al. Simultaneous Probing of Metabolism and Oxygenation of Tumors In Vivo Using FLIM of NAD(P)H and PLIM of a New Polymeric Ir(III) Oxygen Sensor , 2022, International journal of molecular sciences.
[4] Marius Pachitariu,et al. Cellpose 2.0: how to train your own model , 2022, bioRxiv.
[5] Alex J. Walsh,et al. In vivo fluorescence lifetime imaging of macrophage intracellular metabolism during wound responses in zebrafish , 2022, eLife.
[6] Amy K. Erbe,et al. Short-course neoadjuvant in situ vaccination for murine melanoma , 2022, Journal for ImmunoTherapy of Cancer.
[7] Simeon Mayala,et al. Threshold estimation based on local minima for nucleus and cytoplasm segmentation , 2021, BMC Medical Imaging.
[8] Paul A. Wiggins,et al. Omnipose: a high-precision morphology-independent solution for bacterial cell segmentation , 2021, bioRxiv.
[9] Guangyong Peng,et al. NK and NKT cells have distinct properties and functions in cancer , 2021, Oncogene.
[10] R. Sroka,et al. Bioenergetic Alterations of Metabolic Redox Coenzymes as NADH, FAD and FMN by Means of Fluorescence Lifetime Imaging Techniques , 2021, International journal of molecular sciences.
[11] Melissa C. Skala,et al. Extracellular pH affects the fluorescence lifetimes of metabolic co-factors , 2021, Journal of biomedical optics.
[12] Tiffany M. Heaster,et al. Intravital Metabolic Autofluorescence Imaging Captures Macrophage Heterogeneity Across Normal and Cancerous Tissue , 2021, Frontiers in Bioengineering and Biotechnology.
[13] D. Deming,et al. Autofluorescence Imaging of Treatment Response in Neuroendocrine Tumor Organoids , 2021, Cancers.
[14] Amy K. Erbe,et al. Depth of tumor implantation affects response to in situ vaccination in a syngeneic murine melanoma model , 2021, Journal for ImmunoTherapy of Cancer.
[15] E. Ma,et al. Immunometabolism in the Tumor Microenvironment , 2021 .
[16] Marius Pachitariu,et al. Cellpose: a generalist algorithm for cellular segmentation , 2020, Nature Methods.
[17] Jonathan N. Ouellette,et al. Machine Learning Methods for Fluorescence Lifetime Imaging (FLIM) Based Label-Free Detection of Microglia , 2020, Frontiers in Neuroscience.
[18] T. Owonikoko,et al. Disialoganglioside GD2 Expression in Solid Tumors and Role as a Target for Cancer Therapy , 2020, Frontiers in Oncology.
[19] D. Brenner,et al. Metabolic Modulation of Immunity: A New Concept in Cancer Immunotherapy. , 2020, Cell reports.
[20] Howard Y. Chang,et al. Impaired mitochondrial oxidative phosphorylation limits the self-renewal of T cells exposed to persistent antigen , 2020, Nature Immunology.
[21] Joe T. Sharick,et al. Metabolic Heterogeneity in Patient Tumor-Derived Organoids by Primary Site and Drug Treatment , 2020, Frontiers in Oncology.
[22] Melissa C Skala,et al. Fluorescence lifetime imaging microscopy: fundamentals and advances in instrumentation, analysis, and applications , 2020, Journal of biomedical optics.
[23] M. Digman,et al. Caffeine and Cisplatin Effectively Targets the Metabolism of a Triple-Negative Breast Cancer Cell Line Assessed via Phasor-FLIM , 2020, International journal of molecular sciences.
[24] Rupsa Datta,et al. Metabolic mapping of glioblastoma stem cells reveals NADH fluxes associated with glioblastoma phenotype and survival , 2020, Journal of biomedical optics.
[25] Marius Pachitariu,et al. Cellpose: a generalist algorithm for cellular segmentation , 2020, Nature Methods.
[26] R. Deberardinis,et al. We need to talk about the Warburg effect , 2020, Nature Metabolism.
[27] A. Benda,et al. Single-color Fluorescence Lifetime Cross-Correlation Spectroscopy in vivo , 2020, bioRxiv.
[28] Takla Griss,et al. Metabolic Profiling Using Stable Isotope Tracing Reveals Distinct Patterns of Glucose Utilization by Physiologically Activated CD8+ T Cells. , 2019, Immunity.
[29] Liubov E. Shimolina,et al. Interrogation of tumor metabolism in tissue samples ex vivo using fluorescence lifetime imaging of NAD(P)H , 2019, Methods and applications in fluorescence.
[30] J. Powell,et al. Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion , 2019, Science.
[31] T. Shlomi,et al. Intra-Tumoral Metabolic Zonation and Resultant Phenotypic Diversification Are Dictated by Blood Vessel Proximity. , 2019, Cell metabolism.
[32] Joe T. Sharick,et al. Cellular Metabolic Heterogeneity In Vivo Is Recapitulated in Tumor Organoids1 , 2019, Neoplasia.
[33] C. Lyssiotis,et al. Enhanced oxidative phosphorylation in NKT cells is essential for their survival and function , 2019, Proceedings of the National Academy of Sciences.
[34] Christine M. Walsh,et al. Label-free Method for Classification of T cell Activation , 2019, bioRxiv.
[35] K. Quinn,et al. Evaluating Cell Metabolism Through Autofluorescence Imaging of NAD(P)H and FAD. , 2017, Antioxidants & redox signaling.
[36] M. V. Vander Heiden,et al. Quantification of microenvironmental metabolites in murine cancers reveals determinants of tumor nutrient availability , 2018, bioRxiv.
[37] Tiffany M. Heaster,et al. Organotypic microfluidic breast cancer model reveals starvation-induced spatial-temporal metabolic adaptations , 2018, EBioMedicine.
[38] Joanne Li,et al. High-speed imaging of transient metabolic dynamics using two-photon fluorescence lifetime imaging microscopy. , 2018, Optica.
[39] Jeonghan Kim,et al. Intracellular oxygen mapping using a myoglobin-mCherry probe with fluorescence lifetime imaging , 2018, Journal of biomedical optics.
[40] P. Harari,et al. Tumor-Specific Inhibition of In Situ Vaccination by Distant Untreated Tumor Sites , 2018, Cancer Immunology Research.
[41] E. Pearce,et al. Unraveling the Complex Interplay Between T Cell Metabolism and Function. , 2018, Annual review of immunology.
[42] A. Seynhaeve,et al. Intravital Microscopy of Tumor-associated Vasculature Using Advanced Dorsal Skinfold Window Chambers on Transgenic Fluorescent Mice , 2018, Journal of visualized experiments : JoVE.
[43] Yi-Hong Zhou,et al. Tracking Functional Tumor Cell Subpopulations of Malignant Glioma by Phasor Fluorescence Lifetime Imaging Microscopy of NADH , 2017, Cancers.
[44] A. Kimmelman,et al. Metabolic Interactions in the Tumor Microenvironment. , 2017, Trends in cell biology.
[45] Sean C Warren,et al. Context-dependent intravital imaging of therapeutic response using intramolecular FRET biosensors. , 2017, Methods.
[46] Hélio Pedrini,et al. Image Thresholding Improved by Global Optimization Methods , 2017, Appl. Artif. Intell..
[47] G. Koehl,et al. Metabolic Hallmarks of Tumor and Immune Cells in the Tumor Microenvironment , 2017, Front. Immunol..
[48] Jean-Baptiste Galey,et al. Multicolor two-photon imaging of endogenous fluorophores in living tissues by wavelength mixing , 2017, Scientific Reports.
[49] S. Crowe,et al. Regulators of Glucose Metabolism in CD4+ and CD8+ T Cells , 2016, International reviews of immunology.
[50] Roland Eils,et al. Complex heatmaps reveal patterns and correlations in multidimensional genomic data , 2016, Bioinform..
[51] P. Harari,et al. In Situ Tumor Vaccination by Combining Local Radiation and Tumor-Specific Antibody or Immunocytokine Treatments. , 2016, Cancer research.
[52] James Castracane,et al. In Vivo Visualization of Stromal Macrophages via label-free FLIM-based metabolite imaging , 2016, Scientific Reports.
[53] F. D’Acquisto,et al. Lactate Regulates Metabolic and Pro-inflammatory Circuits in Control of T Cell Migration and Effector Functions , 2015, PLoS biology.
[54] K. Svoboda,et al. A Cellular Resolution Map of Barrel Cortex Activity during Tactile Behavior , 2015, Neuron.
[55] Roland Eils,et al. circlize implements and enhances circular visualization in R , 2014, Bioinform..
[56] J. Rathmell,et al. Metabolic Reprogramming towards Aerobic Glycolysis Correlates with Greater Proliferative Ability and Resistance to Metabolic Inhibition in CD8 versus CD4 T Cells , 2014, PloS one.
[57] Peter Carmeliet,et al. Metabolism of stromal and immune cells in health and disease , 2014, Nature.
[58] Kyongbum Lee,et al. Endogenous two-photon fluorescence imaging elucidates metabolic changes related to enhanced glycolysis and glutamine consumption in precancerous epithelial tissues. , 2014, Cancer research.
[59] M. Conroy,et al. Targeting T Cell Immunometabolism for Cancer Immunotherapy; Understanding the Impact of the Tumor Microenvironment , 2014, Front. Oncol..
[60] Stephen B. Howell,et al. In Vivo Time-gated Fluorescence Imaging with Biodegradable Luminescent Porous Silicon Nanoparticles , 2013, Nature Communications.
[61] M. Kinjo,et al. pH Dependence of the Fluorescence Lifetime of FAD in Solution and in Cells , 2013, International journal of molecular sciences.
[62] Alex J. Walsh,et al. Ex vivo optical metabolic measurements from cultured tissue reflect in vivo tissue status , 2012, Journal of biomedical optics.
[63] Irene Georgakoudi,et al. Optical imaging using endogenous contrast to assess metabolic state. , 2012, Annual review of biomedical engineering.
[64] Guillaume Labroille,et al. Multicolor two-photon tissue imaging by wavelength mixing , 2012, Nature Methods.
[65] M. V. Vander Heiden,et al. Aerobic glycolysis: meeting the metabolic requirements of cell proliferation. , 2011, Annual review of cell and developmental biology.
[66] Erika L. Pearce. Metabolism in T cell activation and differentiation. , 2010, Current opinion in immunology.
[67] Melissa C Skala,et al. Longitudinal optical imaging of tumor metabolism and hemodynamics. , 2010, Journal of biomedical optics.
[68] S. Sawilowsky. New Effect Size Rules of Thumb , 2009 .
[69] L. Cantley,et al. Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation , 2009, Science.
[70] T. Gajewski,et al. Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells , 2008, European journal of immunology.
[71] G. Glass. Primary, Secondary, and Meta-Analysis of Research , 2008 .
[72] N. Ramanujam,et al. In vivo multiphoton microscopy of NADH and FAD redox states, fluorescence lifetimes, and cellular morphology in precancerous epithelia , 2007, Proceedings of the National Academy of Sciences.
[73] Joachim Goedhart,et al. Bright monomeric red fluorescent protein with an extended fluorescence lifetime , 2007, Nature Methods.
[74] T. Mak,et al. 12 – The T Cell Receptor: Structure of Its Proteins and Genes , 2006 .
[75] C. Thompson,et al. Activated Akt promotes increased resting T cell size, CD28‐independent T cell growth, and development of autoimmunity and lymphoma , 2003, European journal of immunology.
[76] W. Webb,et al. Live tissue intrinsic emission microscopy using multiphoton-excited native fluorescence and second harmonic generation , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[77] Carla Grandori,et al. Modulation of T‐lymphocyte development, growth and cell size by the Myc antagonist and transcriptional repressor Mad1 , 2002, The EMBO journal.
[78] E. Bröcker,et al. Anatomic location and T-cell stimulatory functions of mouse dendritic cell subsets defined by CD4 and CD8 expression. , 2002, Blood.
[79] W. M. Weaver,et al. A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival. , 2001, Immunity.
[80] Li Wu,et al. CD4 and CD8 Expression by Dendritic Cell Subtypes in Mouse Thymus and Spleen1 , 2000, The Journal of Immunology.
[81] N. Ramanujam. Fluorescence spectroscopy of neoplastic and non-neoplastic tissues. , 2000, Neoplasia.
[82] J. Becker,et al. An antibody-interleukin 2 fusion protein overcomes tumor heterogeneity by induction of a cellular immune response. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[83] K. Takamiya,et al. Isolation of GD3 synthase gene by expression cloning of GM3 alpha-2,8-sialyltransferase cDNA using anti-GD2 monoclonal antibody. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[84] L. Munn,et al. Analysis of lymphocyte activation and proliferation by video microscopy and digital imaging. , 1993, Cytometry.
[85] J. Lakowicz,et al. Fluorescence lifetime imaging of free and protein-bound NADH. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[86] W. Kunz,et al. Contribution of different enzymes to flavoprotein fluorescence of isolated rat liver mitochondria. , 1985, Biochimica et biophysica acta.
[87] K. Aki,et al. Effect of nicotinamide adenine dinucleotide on the oxidation-reduction potentials of lipoamide dehydrogenase from pig heart. , 1984, Journal of biochemistry.
[88] B. Chance,et al. Oxidation-reduction ratio studies of mitochondria in freeze-trapped samples. NADH and flavoprotein fluorescence signals. , 1979, The Journal of biological chemistry.
[89] N. Otsu. A threshold selection method from gray level histograms , 1979 .
[90] S. Silagi. CONTROL OF PIGMENT PRODUCTION IN MOUSE MELANOMA CELLS IN VITRO , 1969, The Journal of cell biology.
[91] O. Warburg. [Origin of cancer cells]. , 1956, Oncologia.
[92] J. Shirlaw. THE METABOLISM OF TUMOURS , 1931 .