Molecular epidemiology and carcinogenesis: endogenous and exogenous carcinogens.
暂无分享,去创建一个
[1] T. Billiar,et al. Nitric Oxide Suppresses Apoptosis via Interrupting Caspase Activation and Mitochondrial Dysfunction in Cultured Hepatocytes* , 1999, The Journal of Biological Chemistry.
[2] G. Pfeifer,et al. Quantitation and mapping of aflatoxin B1-induced DNA damage in genomic DNA using aflatoxin B1-8,9-epoxide and microsomal activation systems. , 1999, Mutation research.
[3] C. Harris,et al. Hepatitis B virus X protein inhibits nucleotide excision repair , 1999, International journal of cancer.
[4] J. Pfeilschifter,et al. Differential regulation of vascular endothelial growth factor and its receptor fms-like-tyrosine kinase is mediated by nitric oxide in rat renal mesangial cells. , 1999, The Biochemical journal.
[5] J. Ford,et al. Hepatitis B x Protein Inhibits p53-dependent DNA Repair in Primary Mouse Hepatocytes* , 1998, The Journal of Biological Chemistry.
[6] A. Riggs,et al. The p53 codon 249 mutational hotspot in hepatocellular carcinoma is not related to selective formation or persistence of aflatoxin B1 adducts , 1998, Oncogene.
[7] C. Harris,et al. p53 and vascular endothelial growth factor regulate tumor growth of NOS2-expressing human carcinoma cells , 1998, Nature Medicine.
[8] M. Buendia,et al. p53-independent apoptotic effects of the hepatitis B virus HBx protein in vivo and in vitro , 1998, Oncogene.
[9] Harris Cc,et al. Molecular epidemiology of human cancer: contribution of mutation spectra studies of tumor suppressor genes. , 1998 .
[10] D. V. van Thiel,et al. Pathogenesis of hepatitis B and C‐induced hepatocellular carcinoma , 1998, Journal of viral hepatitis.
[11] E. Masini,et al. Role of nitric oxide in angiogenesis and tumor progression in head and neck cancer. , 1998, Journal of the National Cancer Institute.
[12] C. Harris,et al. Frequent nitric oxide synthase-2 expression in human colon adenomas: implication for tumor angiogenesis and colon cancer progression. , 1998, Cancer research.
[13] Y. Yun,et al. X-gene Product of Hepatitis B Virus Induces Apoptosis in Liver Cells* , 1998, The Journal of Biological Chemistry.
[14] C. Harris,et al. Hepatitis B virus X protein and p53 tumor suppressor interactions in the modulation of apoptosis. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[15] P. Hainaut,et al. Hepatocellular carcinoma: from gene to public health. , 1997, Journal of the National Cancer Institute.
[16] G. Garcı́a-Cardeña,et al. Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells. , 1997, The Journal of clinical investigation.
[17] K. Koike,et al. Cytoplasmic retention of the p53 tumor suppressor gene product is observed in the hepatitis B virus X gene-transfected cells , 1997, Oncogene.
[18] Chien-Jen Chen,et al. Epidemiological characteristics and risk factors of hepatocellular carcinoma , 1997, Journal of gastroenterology and hepatology.
[19] Richard Graham Knowles,et al. Selective inhibition of inducible nitric oxide synthase inhibits tumor growth in vivo: studies with 1400W, a novel inhibitor. , 1997, Cancer research.
[20] H. Tajiri,et al. Induction of vascular endothelial growth factor by nitric oxide in human glioblastoma and hepatocellular carcinoma cells , 1997, Oncogene.
[21] C. Harris,et al. Aflatoxin B1-induced DNA adduct formation and p53 mutations in CYP450-expressing human liver cell lines. , 1997, Carcinogenesis.
[22] Jen-kun Lin,et al. Suppression of nitric oxide–induced apoptosis by N‐acetyl‐l‐cysteine through modulation of glutathione, bcl‐2, and bax protein levels , 1997, Molecular carcinogenesis.
[23] S. Ambs,et al. Chronic hepatitis C virus infection in humans: induction of hepatic nitric oxide synthase and proposed mechanisms for carcinogenesis. , 1997, The Journal of surgical research.
[24] C. Harris,et al. Interactive effects of nitric oxide and the p 53 tumor suppressor gene in carcinogenesis and tumor progression , 2004 .
[25] G. Wogan,et al. UV-induced mutagenesis of human p53 in a vector replicated in Saccharomyces cerevisiae. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[26] G. Tozer,et al. Inhibition of nitric oxide synthase induces a selective reduction in tumor blood flow that is reversible with L-arginine. , 1997, Cancer research.
[27] M. Nehls,et al. Suppression of Apoptosis by Nitric Oxide via Inhibition of Interleukin-1β–converting Enzyme (ICE)-like and Cysteine Protease Protein (CPP)-32–like Proteases , 1997, The Journal of experimental medicine.
[28] Simon C Watkins,et al. Constitutive expression of inducible nitric oxide synthase in the mouse ileal mucosa. , 1997, The American journal of physiology.
[29] S. Tannenbaum,et al. The role of nitric oxide (NO.) in the carcinogenic process. , 1996, Biochimica et biophysica acta.
[30] B. Brüne,et al. Nitric oxide-induced apoptosis: p53-dependent and p53-independent signalling pathways. , 1996, The Biochemical journal.
[31] J. Jiricny,et al. Base analog and neighboring base effects on substrate specificity of recombinant human G:T mismatch-specific thymine DNA-glycosylase. , 1996, Biochemistry.
[32] J. Weidner,et al. Expression of inducible nitric oxide synthase and nitrotyrosine in colonic epithelium in inflammatory bowel disease. , 1996, Gastroenterology.
[33] M. Hentze,et al. Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[34] E. Fontham,et al. Inducible nitric oxide synthase, nitrotyrosine, and apoptosis in Helicobacter pylori gastritis: effect of antibiotics and antioxidants. , 1996, Cancer research.
[35] M. Oren,et al. p53 in growth control and neoplasia. , 1996, Biochimica et biophysica acta.
[36] C. Harris,et al. The XPB and XPD DNA helicases are components of the p53-mediated apoptosis pathway. , 1996, Genes & development.
[37] C. Harris,et al. An aflatoxin-associated mutational hotspot at codon 249 in the p53 tumor suppressor gene occurs in hepatocellular carcinomas from Mexico. , 1996, Carcinogenesis.
[38] C. Harris,et al. Nitric oxide-induced p53 accumulation and regulation of inducible nitric oxide synthase expression by wild-type p53. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[39] H. Whittle,et al. Aflatoxin exposure and cytogenetic alterations in individuals from the Gambia, West Africa. , 1996, Mutation research.
[40] Harris Cc,et al. The 1995 Walter Hubert Lecture--molecular epidemiology of human cancer: insights from the mutational analysis of the p53 tumour-suppressor gene. , 1996, British Journal of Cancer.
[41] C. Harris,et al. Abrogation of p53-induced apoptosis by the hepatitis B virus X gene. , 1995, Cancer research.
[42] H. Loiseau,et al. Differential expression of inducible nitric oxide synthase mRNA in human brain tumours , 1995, Neuroreport.
[43] A. Sica,et al. A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter , 1995, The Journal of experimental medicine.
[44] V. Wahn,et al. Nitric oxide induces apoptosis in mouse thymocytes. , 1995, Journal of immunology.
[45] S. Erzurum,et al. Continuous nitric oxide synthesis by inducible nitric oxide synthase in normal human airway epithelium in vivo. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[46] Richard Graham Knowles,et al. Nitric oxide synthase activity in human breast cancer. , 1995, British Journal of Cancer.
[47] C. Prives,et al. Activation of p53 sequence-specific DNA bindingby short single strands of DNA requires the p53 C-terminus , 1995, Cell.
[48] C. Harris,et al. Effects of p53 mutants on wild-type p53-mediated transactivation are cell type dependent. , 1995, Oncogene.
[49] A. Levine,et al. Human TAFII31 protein is a transcriptional coactivator of the p53 protein. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[50] P Rhodes,et al. Roles of nitric oxide in tumor growth. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[51] S. Friend,et al. Mutational analysis of the carboxy-terminal portion of p53 using both yeast and mammalian cell assays in vivo. , 1995, Oncogene.
[52] N. Pavletich,et al. Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms , 1995, Science.
[53] K. Isselbacher,et al. p53-mediated cellular response to DNA damage in cells with replicative hepatitis B virus. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[54] K. Aldape,et al. Expression of nitric oxide synthase in human central nervous system tumors. , 1995, Cancer research.
[55] C. Arrowsmith,et al. Solution structure of the tetrameric minimum transforming domain of p53 , 1995, Nature Structural Biology.
[56] C. Bréchot,et al. Selective accumulation of the X transcript of hepatitis B virus in patients negative for hepatitis B surface antigen with hepatocellular carcinoma , 1995, Hepatology.
[57] A. Gronenborn,et al. HIGH-RESOLUTION SOLUTION STRUCTURE OF THE OLIGOMERIZATION DOMAIN OF P53 BY MULTI-DIMENSIONAL NMR , 1995 .
[58] R. Tjian,et al. p53 transcriptional activation mediated by coactivators TAFII40 and TAFII60. , 1995, Science.
[59] A. Levine,et al. Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression , 1995, Molecular and cellular biology.
[60] B. Brüne,et al. p53 expression in nitric oxide‐induced apoptosis , 1994, FEBS letters.
[61] R. Schneider,et al. Hepatitis B virus HBx protein activates Ras-GTP complex formation and establishes a Ras, Raf, MAP kinase signaling cascade. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[62] D. Lane,et al. Allosteric activation of latent p53 tetramers , 1994, Current Biology.
[63] Carl Nathan,et al. Nitric oxide synthases: Roles, tolls, and controls , 1994, Cell.
[64] C. Harris,et al. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. , 1994, Cancer research.
[65] P. Cerutti,et al. Oxy-radical induced mutagenesis of hotspot codons 248 and 249 of the human p53 gene. , 1994, Oncogene.
[66] T. Kunkel,et al. Error-prone replication of repeated DNA sequences by T7 DNA polymerase in the absence of its processivity subunit. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[67] A. Gronenborn,et al. High-resolution structure of the oligomerization domain of p53 by multidimensional NMR. , 1994, Science.
[68] John Calvin Reed,et al. Identification of a p53-dependent negative response element in the bcl-2 gene. , 1994, Cancer research.
[69] C. Harris,et al. Geographic variation of p53 mutational profile in nonmalignant human liver. , 1994, Science.
[70] A. Levine,et al. Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein. , 1994, Genes & development.
[71] F. Ponchel,et al. Hepatocarcinoma-specific mutant p53-249ser induces mitotic activity but has no effect on transforming growth factor beta 1-mediated apoptosis. , 1994, Cancer research.
[72] T. Soussi,et al. Multifactorial analysis of p53 alteration in human cancer: A review , 1994, International journal of cancer.
[73] H. Maeda,et al. Enhanced Vascular Permeability in Solid Tumor Is Mediated by Nitric Oxide and Inhibited by Both New Nitric Oxide Scavenger and Nitric Oxide Synthase Inhibitor , 1994, Japanese journal of cancer research : Gann.
[74] C. Harris,et al. Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[75] H. Bartsch,et al. Chronic infections and inflammatory processes as cancer risk factors: possible role of nitric oxide in carcinogenesis. , 1994, Mutation research.
[76] Richard Graham Knowles,et al. Nitric oxide synthase activity in human gynecological cancer. , 1994, Cancer research.
[77] K. Isselbacher,et al. Genetic heterogeneity of hepatocellular carcinoma. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[78] L. Szekely,et al. p53 binds single-stranded DNA ends and catalyzes DNA renaturation and strand transfer. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[79] C. Harris,et al. p53: at the crossroads of molecular carcinogenesis and risk assessment. , 1993, Science.
[80] P. Cerutti,et al. Aflatoxin B1 induces the transversion of G-->T in codon 249 of the p53 tumor suppressor gene in human hepatocytes. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[81] P Tomboulian,et al. Diffusion of nitric oxide in the aorta wall monitored in situ by porphyrinic microsensors. , 1993, Biochemical and biophysical research communications.
[82] M. Subler,et al. p53 binds to the TATA-binding protein-TATA complex. , 1993, The Journal of biological chemistry.
[83] M. Marletta,et al. Nitric oxide synthase structure and mechanism. , 1993, The Journal of biological chemistry.
[84] C. Miller,et al. The p53 activation domain binds the TATA box-binding polypeptide in Holo-TFIID, and a neighboring p53 domain inhibits transcription , 1993, Molecular and cellular biology.
[85] J. Pipas,et al. Specific repression of TATA-mediated but not initiator-mediated transcription by wild-type p53 , 1993, Nature.
[86] M. Zhu,et al. Hepatitis B x antigen and p53 are associated in vitro and in liver tissues from patients with primary hepatocellular carcinoma. , 1993, Oncogene.
[87] C. Ingles,et al. Direct interaction between the transcriptional activation domain of human p53 and the TATA box-binding protein. , 1993, The Journal of biological chemistry.
[88] Y. Cao,et al. Aberrations of p53 gene in human hepatocellular carcinoma from China. , 1993, Carcinogenesis.
[89] G. Zambetti,et al. Wild-type p53 binds to the TATA-binding protein and represses transcription. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[90] Bert Vogelstein,et al. p53 function and dysfunction , 1992, Cell.
[91] B. Henderson,et al. Urinary aflatoxin biomarkers and risk of hepatocellular carcinoma , 1992, The Lancet.
[92] R. Iggo,et al. Mammalian p53 can function as a transcription factor in yeast. , 1992, Nucleic acids research.
[93] B. Slagle,et al. p53 mutations cluster at codon 249 in hepatitis B virus-positive hepatocellular carcinomas from China. , 1992, Cancer research.
[94] A. Puisieux,et al. Selective targeting of p53 gene mutational hotspots in human cancers by etiologically defined carcinogens. , 1991, Cancer research.
[95] S. Tabata,et al. Evidence for increased in vitro recombination with insertion of human hepatitis B virus DNA. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[96] B. Vogelstein,et al. p53 mutations in human cancers. , 1991, Science.
[97] A. Levine,et al. The p53 tumour suppressor gene , 1991, Nature.
[98] S. Moncada,et al. Nitric oxide: physiology, pathophysiology, and pharmacology. , 1991, Pharmacological reviews.
[99] A. Siddiqui,et al. HBV X protein alters the DNA binding specificity of CREB and ATF-2 by protein-protein interactions , 1991, Science.
[100] R. A. Metcalf,et al. Mutational hot spot in the p53 gene in human hepatocellular carcinomas , 1991, Nature.
[101] J. Wands,et al. Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa , 1991, Nature.
[102] Yumay Chen,et al. Genetic mechanisms of tumor suppression by the human p53 gene , 1990, Science.
[103] B. Vogelstein,et al. p53 functions as a cell cycle control protein in osteosarcomas , 1990, Molecular and cellular biology.
[104] G. Lozano,et al. Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene. , 1990, Science.
[105] S. Fields,et al. Presence of a potent transcription activating sequence in the p53 protein. , 1990, Science.
[106] B. Vogelstein,et al. Suppression of human colorectal carcinoma cell growth by wild-type p53. , 1990, Science.
[107] E. Appella,et al. Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[108] T. Soussi,et al. Structural aspects of the p53 protein in relation to gene evolution. , 1990, Oncogene.
[109] P. Hofschneider,et al. A trans-activator function is generated by integration of hepatitis B virus preS/S sequences in human hepatocellular carcinoma DNA. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[110] P. Hofschneider,et al. The preS2/S region of integrated hepatitis B virus DNA encodes a transcriptional transactivator , 1990, Nature.
[111] B. Freeman,et al. Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[112] M. Oren,et al. Wild-type p53 can inhibit oncogene-mediated focus formation. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[113] K. Koike,et al. The × Gene of Hepatitis B Virus Induced Growth Stimulation and Tumorigenic Transformation of Mouse NIH3T3 Cells , 1989, Japanese journal of cancer research : Gann.
[114] A. Levine,et al. The p53 proto-oncogene can act as a suppressor of transformation , 1989, Cell.
[115] B. Henderson,et al. Hepatitis B virus, aflatoxins, and hepatocellular carcinoma in southern Guangxi, China. , 1989, Cancer research.
[116] B. Ames,et al. Detection of DNA adducts by high-performance liquid chromatography with electrochemical detection. , 1989, Carcinogenesis.
[117] A. Levine,et al. Mutation is required to activate the p53 gene for cooperation with the ras oncogene and transformation , 1989, Journal of virology.
[118] O. Hino,et al. Instability of integrated hepatitis B virus DNA with inverted repeat structure in a transgenic mouse. , 1989, Cancer genetics and cytogenetics.
[119] Rotter,et al. Meth A fibrosarcoma cells express two transforming mutant p53 species. , 1988, Oncogene.
[120] A. Levine,et al. Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life , 1988, Molecular and cellular biology.
[121] D. Spandau,et al. trans-activation of viral enhancers by the hepatitis B virus X protein , 1988, Journal of virology.
[122] J. Twu,et al. Transcriptional trans-activating function of hepatitis B virus , 1987, Journal of virology.
[123] J. Kaldor,et al. Aflatoxin exposure, hepatitis b virus infection and liver cancer in swaziland , 1987, International journal of cancer.
[124] I. Purchase,et al. Hepatocellular carcinoma and dietary aflatoxin in Mozambique and Transkei. , 1985, British Journal of Cancer.
[125] V. Rotter,et al. Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation , 1984, Nature.
[126] P. Gruss,et al. Participation of p53 cellular tumour antigen in transformation of normal embryonic cells , 1984, Nature.
[127] J. Jenkins,et al. Cellular immortalization by a cDNA clone encoding the transformation-associated phosphoprotein p53 , 1984, Nature.
[128] V. Rotter,et al. Reconstitution of p53 expression in a nonproducer Ab-MuLV-transformed cell line by transfection of a functional p53 gene , 1984, Cell.
[129] C. Harris,et al. Activation of chemical carcinogens by cultured human fetal liver, esophagus and stomach. , 1984, Chemico-biological interactions.
[130] L. Salamat,et al. A case-control dietary study of primary liver cancer risk from aflatoxin exposure. , 1982, International journal of epidemiology.
[131] Lu-Yu Hwang,et al. HEPATOCELLULAR CARCINOMA AND HEPATITIS B VIRUS A Prospective Study of 22 707 Men in Taiwan , 1981, The Lancet.
[132] Patricia Rodriguez-Tomé,et al. IARC Database of p53 gene mutations in human tumors and cell lines: updated compilation, revised formats and new visualisation tools , 1998, Nucleic Acids Res..
[133] C. Harris,et al. Radon and lung carcinogenesis: mutability of p53 codons 249 and 250 to 238Pu alpha-particles in human bronchial epithelial cells. , 1997, Carcinogenesis.
[134] James B. Mitchell,et al. Chemical biology of nitric oxide: regulation and protective and toxic mechanisms. , 1996, Current topics in cellular regulation.
[135] Thierry Soussi,et al. Somatic point mutations in the p53 gene of human tumors and cell lines: updated compilation , 1996, Nucleic Acids Res..
[136] M. Evans,et al. p53 modulation of TFIIH–associated nucleotide excision repair activity , 1995, Nature Genetics.
[137] S. Ullrich,et al. Functional inactivation but not structural mutation of p53 causes liver cancer , 1995, Nature Genetics.
[138] B. Brüne,et al. Mechanisms for nitric oxide-induced cell death: involvement of apoptosis. , 1995, Advances in neuroimmunology.
[139] W. Robinson,et al. Molecular events in the pathogenesis of hepadnavirus-associated hepatocellular carcinoma. , 1994, Annual review of medicine.
[140] C. Harris. Solving the viral-chemical puzzle of human liver carcinogenesis. , 1994, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
[141] S. Snyder,et al. Nitric oxide: a physiologic messenger molecule. , 1994, Annual review of biochemistry.
[142] P. Cerutti,et al. Mutagenesis of codon 248 of the human p53 tumor suppressor gene by N-ethyl-N-nitrosourea. , 1994, Oncogene.
[143] B. Henderson,et al. A follow-up study of urinary markers of aflatoxin exposure and liver cancer risk in Shanghai, People's Republic of China. , 1994, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
[144] S. N. Agoff,et al. Regulation of the human hsp70 promoter by p53. , 1993, Science.