IgA Pemphigus: Subcorneal Pustular Dermatosis Type - A case report with vesicle and pustular eruption for 13 years cured with dapsone in 3 weeks

IgA pemphigus is a newly characterized group of autoimmune intraepidermal blistering diseases presenting as vesiculopustular eruptions with a predilection in axillary and groin areas. Immunopathologically, IgA deposition in the intercellular space of the epidermis is present in all cases of IgA pemphigus by direct immunofluorescence. However, unlike pemphigus vulgaris, IgA pemphigus carries a relatively benign course. Herein we reported a case of subcorneal pustular dermatosis type IgA pemphigus associated with monoclonal IgA gammopathy. The eruptions cleared with dapsone 50 mg daily for three weeks and no recurrence was found after 6-months follow-up.

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