Synthesis of a hydrolytically stable, fluorescent-labeled ATP analog as a tool for probing adenylyl cyclases.

[1]  R. Seifert,et al.  Distinct interactions of 2'- and 3'-O-(N-methyl)anthraniloyl-isomers of ATP and GTP with the adenylyl cyclase toxin of Bacillus anthracis, edema factor. , 2009, Biochemical pharmacology.

[2]  C. Müller,et al.  Synthesis of uracil nucleotide analogs with a modified, acyclic ribose moiety as P2Y(2) receptor antagonists. , 2009, Bioorganic & medicinal chemistry.

[3]  R. Seifert,et al.  Characterization of Mouse Heart Adenylyl Cyclase , 2009, Journal of Pharmacology and Experimental Therapeutics.

[4]  R. Seifert,et al.  Molecular Analysis of the Interaction of Anthrax Adenylyl Cyclase Toxin, Edema Factor, with 2′(3′)-O-(N-(methyl)anthraniloyl)-Substituted Purine and Pyrimidine Nucleotides , 2009, Molecular Pharmacology.

[5]  Jochen Buck,et al.  Structure-based development of novel adenylyl cyclase inhibitors. , 2008, Journal of medicinal chemistry.

[6]  C. Müller,et al.  Structure-activity relationships of anthraquinone derivatives derived from bromaminic acid as inhibitors of ectonucleoside triphosphate diphosphohydrolases (E-NTPDases) , 2008, Purinergic Signalling.

[7]  R. Seifert,et al.  Molecular Analysis of the Interaction of Bordetella pertussis Adenylyl Cyclase with Fluorescent Nucleotides , 2007, Molecular Pharmacology.

[8]  C. Müller,et al.  Synthesis and structure-activity relationships of uracil nucleotide derivatives and analogues as agonists at human P2Y2, P2Y4, and P2Y6 receptors. , 2006, Journal of medicinal chemistry.

[9]  Roland Seifert,et al.  Broad Specificity of Mammalian Adenylyl Cyclase for Interaction with 2′,3′-Substituted Purine- and Pyrimidine Nucleotide Inhibitors , 2006, Molecular Pharmacology.

[10]  J. Millán Alkaline Phosphatases , 2006, Purinergic Signalling.

[11]  C. Müller,et al.  Synthesis and preliminary evaluation of [3H]PSB-0413, a selective antagonist radioligand for platelet P2Y12 receptors. , 2005, Bioorganic & medicinal chemistry letters.

[12]  Roland Seifert,et al.  Structural Basis for the Inhibition of Mammalian Membrane Adenylyl Cyclase by 2 ′(3′)-O-(N-Methylanthraniloyl)-guanosine 5 ′-Triphosphate* , 2005, Journal of Biological Chemistry.

[13]  K. Iwatsubo,et al.  Direct Inhibition of Type 5 Adenylyl Cyclase Prevents Myocardial Apoptosis without Functional Deterioration* , 2004, Journal of Biological Chemistry.

[14]  D. Sauer,et al.  Microwave-assisted synthesis utilizing supported reagents: a rapid and efficient acylation procedure. , 2003, Organic letters.

[15]  Andreas Link,et al.  Structural and mechanistic basis of pre- and posttransfer editing by leucyl-tRNA synthetase. , 2003, Molecular cell.

[16]  A. Link,et al.  Improving an antitrypanosomal lead applying nucleophilic substitution on a safety catch linker. , 2002, Bioorganic & medicinal chemistry.

[17]  K. Burgess,et al.  Syntheses of nucleoside triphosphates. , 2000, Chemical reviews.

[18]  J. Eccleston,et al.  [18] Fluorescent nucleotide analogs: Synthesis and applications , 1997 .

[19]  T. Hiratsuka New ribose-modified fluorescent analogs of adenine and guanine nucleotides available as substrates for various enzymes. , 1983, Biochimica et biophysica acta.

[20]  S. Leppla,et al.  Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[21]  M. Yoshikawa,et al.  A novel method for phosphorylation of nucleosides to 5'-nucleotides. , 1967, Tetrahedron letters.