Synthesis of a hydrolytically stable, fluorescent-labeled ATP analog as a tool for probing adenylyl cyclases.
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[1] R. Seifert,et al. Distinct interactions of 2'- and 3'-O-(N-methyl)anthraniloyl-isomers of ATP and GTP with the adenylyl cyclase toxin of Bacillus anthracis, edema factor. , 2009, Biochemical pharmacology.
[2] C. Müller,et al. Synthesis of uracil nucleotide analogs with a modified, acyclic ribose moiety as P2Y(2) receptor antagonists. , 2009, Bioorganic & medicinal chemistry.
[3] R. Seifert,et al. Characterization of Mouse Heart Adenylyl Cyclase , 2009, Journal of Pharmacology and Experimental Therapeutics.
[4] R. Seifert,et al. Molecular Analysis of the Interaction of Anthrax Adenylyl Cyclase Toxin, Edema Factor, with 2′(3′)-O-(N-(methyl)anthraniloyl)-Substituted Purine and Pyrimidine Nucleotides , 2009, Molecular Pharmacology.
[5] Jochen Buck,et al. Structure-based development of novel adenylyl cyclase inhibitors. , 2008, Journal of medicinal chemistry.
[6] C. Müller,et al. Structure-activity relationships of anthraquinone derivatives derived from bromaminic acid as inhibitors of ectonucleoside triphosphate diphosphohydrolases (E-NTPDases) , 2008, Purinergic Signalling.
[7] R. Seifert,et al. Molecular Analysis of the Interaction of Bordetella pertussis Adenylyl Cyclase with Fluorescent Nucleotides , 2007, Molecular Pharmacology.
[8] C. Müller,et al. Synthesis and structure-activity relationships of uracil nucleotide derivatives and analogues as agonists at human P2Y2, P2Y4, and P2Y6 receptors. , 2006, Journal of medicinal chemistry.
[9] Roland Seifert,et al. Broad Specificity of Mammalian Adenylyl Cyclase for Interaction with 2′,3′-Substituted Purine- and Pyrimidine Nucleotide Inhibitors , 2006, Molecular Pharmacology.
[10] J. Millán. Alkaline Phosphatases , 2006, Purinergic Signalling.
[11] C. Müller,et al. Synthesis and preliminary evaluation of [3H]PSB-0413, a selective antagonist radioligand for platelet P2Y12 receptors. , 2005, Bioorganic & medicinal chemistry letters.
[12] Roland Seifert,et al. Structural Basis for the Inhibition of Mammalian Membrane Adenylyl Cyclase by 2 ′(3′)-O-(N-Methylanthraniloyl)-guanosine 5 ′-Triphosphate* , 2005, Journal of Biological Chemistry.
[13] K. Iwatsubo,et al. Direct Inhibition of Type 5 Adenylyl Cyclase Prevents Myocardial Apoptosis without Functional Deterioration* , 2004, Journal of Biological Chemistry.
[14] D. Sauer,et al. Microwave-assisted synthesis utilizing supported reagents: a rapid and efficient acylation procedure. , 2003, Organic letters.
[15] Andreas Link,et al. Structural and mechanistic basis of pre- and posttransfer editing by leucyl-tRNA synthetase. , 2003, Molecular cell.
[16] A. Link,et al. Improving an antitrypanosomal lead applying nucleophilic substitution on a safety catch linker. , 2002, Bioorganic & medicinal chemistry.
[17] K. Burgess,et al. Syntheses of nucleoside triphosphates. , 2000, Chemical reviews.
[18] J. Eccleston,et al. [18] Fluorescent nucleotide analogs: Synthesis and applications , 1997 .
[19] T. Hiratsuka. New ribose-modified fluorescent analogs of adenine and guanine nucleotides available as substrates for various enzymes. , 1983, Biochimica et biophysica acta.
[20] S. Leppla,et al. Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells. , 1982, Proceedings of the National Academy of Sciences of the United States of America.
[21] M. Yoshikawa,et al. A novel method for phosphorylation of nucleosides to 5'-nucleotides. , 1967, Tetrahedron letters.