Systemic Gene Delivery by Single-Dose Intracardiac Administration of scAAV2/9 and scAAV2/rh10 Variants in Newborn Rats.
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E. Bézard | M. Bourdenx | S. Dovero | B. Dehay | M. Canron | L. Chansel-Debordeaux | N. Dutheil | C. Jimenez
[1] E. Bézard,et al. In utero delivery of rAAV2/9 induces neuronal expression of the transgene in the brain: towards new models of Parkinson’s disease , 2017, Gene Therapy.
[2] Tianyun Wang,et al. RETRACTED ARTICLE: Impact of different promoters, promoter mutation, and an enhancer on recombinant protein expression in CHO cells , 2017, Scientific Reports.
[3] R. Chandler,et al. Recombinant Adeno-Associated Viral Integration and Genotoxicity: Insights from Animal Models. , 2017, Human gene therapy.
[4] Y. Saga,et al. Optimization of adeno-associated virus vector-mediated gene transfer to the respiratory tract , 2017, Gene Therapy.
[5] E. Bézard,et al. Endosulfine-alpha inhibits membrane-induced α-synuclein aggregation and protects against α-synuclein neurotoxicity , 2017, Acta neuropathologica communications.
[6] Samantha Parker,et al. Adeno-Associated Virus-Based Gene Therapy for CNS Diseases , 2016, Human gene therapy.
[7] J. Prieto,et al. Recombinant AAV Integration Is Not Associated With Hepatic Genotoxicity in Nonhuman Primates and Patients. , 2016, Molecular therapy : the journal of the American Society of Gene Therapy.
[8] Axel Rossi,et al. Intégration des vecteurs AAV et mutagenèse insertionnelle , 2016 .
[9] K. Masamoto,et al. Establishment and evaluation of a new highly metastatic tumor cell line 5a-D-Luc-ZsGreen expressing both luciferase and green fluorescent protein. , 2016, International journal of oncology.
[10] Qin Li,et al. Lack of additive role of ageing in nigrostriatal neurodegeneration triggered by α-synuclein overexpression , 2015, Acta neuropathologica communications.
[11] Chang Hoon Shin,et al. Overexpression of microRNA-95-3p suppresses brain metastasis of lung adenocarcinoma through downregulation of cyclin D1 , 2015, Oncotarget.
[12] E. Bézard,et al. Systemic gene delivery to the central nervous system using Adeno-associated virus , 2014, Front. Mol. Neurosci..
[13] S. Salvador,et al. Immunohistochemical, tomographic, and histological study on onlay bone graft remodeling. Part III: allografts. , 2013, Clinical oral implants research.
[14] M. Levivier,et al. A next step in adeno‐associated virus‐mediated gene therapy for neurological diseases: regulation and targeting , 2013, British journal of clinical pharmacology.
[15] R. Muschel,et al. Ultrasonography-guided intracardiac injection: an improvement for quantitative brain colonization assays. , 2013, The American journal of pathology.
[16] E. Bézard,et al. Levodopa gains psychostimulant‐like properties after nigral dopaminergic loss , 2013, Annals of neurology.
[17] D. Borchelt,et al. Capsid Serotype and Timing of Injection Determines AAV Transduction in the Neonatal Mice Brain , 2013, PloS one.
[18] S. Muramatsu,et al. Systemic Delivery of Tyrosine-Mutant AAV Vectors Results in Robust Transduction of Neurons in Adult Mice , 2013, BioMed research international.
[19] R. Samulski,et al. Viral vectors for gene delivery to the central nervous system , 2012, Neurobiology of Disease.
[20] W. Low,et al. Lysosomal enzyme can bypass the blood-brain barrier and reach the CNS following intranasal administration. , 2012, Molecular genetics and metabolism.
[21] Qin Li,et al. Systemic scAAV9 variant mediates brain transduction in newborn rhesus macaques , 2012, Scientific Reports.
[22] A. Baiker,et al. Universal real-time PCR for the detection and quantification of adeno-associated virus serotype 2-derived inverted terminal repeat sequences. , 2012, Human gene therapy methods.
[23] Ruhang Tang,et al. Single tyrosine mutation in AAV8 and AAV9 capsids is insufficient to enhance gene delivery to skeletal muscle and heart. , 2012, Human gene therapy methods.
[24] J. Flannery,et al. Enhanced gene delivery to the neonatal retina through systemic administration of tyrosine-mutated AAV9 , 2011, Gene Therapy.
[25] J. Grieger,et al. Robust spinal motor neuron transduction following intrathecal delivery of AAV9 in pigs , 2011, Gene Therapy.
[26] E. Bézard,et al. Endogenous morphine-like compound immunoreactivity increases in parkinsonism. , 2011, Brain : a journal of neurology.
[27] W. Hauswirth,et al. Novel properties of tyrosine-mutant AAV2 vectors in the mouse retina. , 2011, Molecular therapy : the journal of the American Society of Gene Therapy.
[28] S. Zolotukhin,et al. High-efficiency transduction and correction of murine hemophilia B using AAV2 vectors devoid of multiple surface-exposed tyrosines. , 2010, Molecular therapy : the journal of the American Society of Gene Therapy.
[29] G. Jayandharan,et al. High-efficiency transduction of fibroblasts and mesenchymal stem cells by tyrosine-mutant AAV2 vectors for their potential use in cellular therapy. , 2010, Human gene therapy.
[30] D. Duan,et al. Adeno-associated virus serotype 6 capsid tyrosine-to-phenylalanine mutations improve gene transfer to skeletal muscle. , 2010, Human gene therapy.
[31] L. Zhong,et al. Enhanced long-term transduction and multilineage engraftment of human hematopoietic stem cells transduced with tyrosine-modified recombinant adeno-associated virus serotype 2. , 2010, Human gene therapy.
[32] P. Pivirotto,et al. Eight years of clinical improvement in MPTP-lesioned primates after gene therapy with AAV2-hAADC. , 2010, Molecular therapy : the journal of the American Society of Gene Therapy.
[33] M. Rich,et al. Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN , 2010, Nature Biotechnology.
[34] J. Fyfe,et al. Intravenous administration of self-complementary AAV9 enables transgene delivery to adult motor neurons. , 2009, Molecular therapy : the journal of the American Society of Gene Therapy.
[35] Andrew King,et al. Staging/typing of Lewy body related α-synuclein pathology: a study of the BrainNet Europe Consortium , 2009, Acta Neuropathologica.
[36] J. Wilson,et al. Tailoring the AAV vector capsid for gene therapy , 2009, Gene Therapy.
[37] K. Foust,et al. Intravascular AAV9 preferentially targets neonatal neurons and adult astrocytes , 2009, Nature Biotechnology.
[38] H. Sweeney,et al. Adeno-associated virus (AAV) serotype 9 provides global cardiac gene transfer superior to AAV1, AAV6, AAV7, and AAV8 in the mouse and rat. , 2008, Human gene therapy.
[39] N. Muzyczka,et al. Next generation of adeno-associated virus 2 vectors: Point mutations in tyrosines lead to high-efficiency transduction at lower doses , 2008, Proceedings of the National Academy of Sciences.
[40] R. H. Smith. Adeno-associated virus integration: virus versus vector , 2008, Gene Therapy.
[41] D. Jenkins,et al. Bioluminescent human breast cancer cell lines that permit rapid and sensitive in vivo detection of mammary tumors and multiple metastases in immune deficient mice , 2005, Breast Cancer Research.
[42] F. Gage,et al. Retrograde Viral Delivery of IGF-1 Prolongs Survival in a Mouse ALS Model , 2003, Science.
[43] L. V. von Segesser,et al. Adeno-associated virus (AAV) vectors achieve prolonged transgene expression in mouse myocardium and arteries in vivo: a comparative study with adenovirus vectors. , 2003, International journal of cardiology.
[44] Theresa A. Storm,et al. AAV serotype 2 vectors preferentially integrate into active genes in mice , 2003, Nature Genetics.
[45] M. King,et al. Dose and Promoter Effects of Adeno-Associated Viral Vector for Green Fluorescent Protein Expression in the Rat Brain , 2002, Experimental Neurology.
[46] B. Byrne,et al. Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield , 1999, Gene Therapy.