The characteristics of a helicopter-borne lidar based on tunable TEA CO2 laser and its third harmonic designed for remote detecting the methane and ammonia leakages from pipe-lines are analyzed numerically. The spectral range near 3 micrometers is shown to be most promising for remote sensing of methane emissions. Parameters of radiation of the tunable pulse-periodic mini-TEA CO2 laser and generators of harmonics to be utilized in the helicopter-borne differential absorption lidar are estimated. Emissions of different gases intensity are analyzed for possible detectability at a distance up to 1 km. The use of the third harmonic of the TEA CO2 laser allows methane emissions from a pipe-line to be detected and measured with mean measurement error from 10 to 15% for methane concentrations varying from the background level to the explosion-hazardous one. The optimal pair and possibilities of the ammonia remote sensing on the base of the first harmonic of TEA CO2 laser was determined as well.