Antioxidant Potential of Polyphenols: In Need for Critical Assessment of In Vitro Results

Antioxidants have become OTC (Over the Counter) prophylactic dietary supplements hit of the 21st century. Polyphenols, including flavonoids and phenolic acids, are widely distributed antioxidants and are present in medicinal drugs, fruits and vegetables (food) e.g. propolis, wine, chocolate….Individuals tend to reach for polyphenols as a source of longevity which can be related to their ability to reduce oxidative stress. Oxidative stress has been postulated as a cause of many diseases e.g. rheumatoid arthritis, diabetes, skin diseases, cataract, Alzheimer and Parkinson disease… Question that we often face is how effective commercially available product as antioxidants is. Predominantly this answer is gained through in vitro testing that includes spectrophotometry and chromatography.