Ultraviolet B radiation-induced JPH203-loaded keratinocyte extracellular vesicles exert etiological interventions for psoriasis therapy.

[1]  Ruijie Chen,et al.  Water-responsive gel extends drug retention and facilitates skin penetration for curcumin topical delivery against psoriasis , 2023, Asian journal of pharmaceutical sciences.

[2]  Ruijie Chen,et al.  Glutamine‐Based Metabolism Normalization and Oxidative Stress Alleviation by Self‐Assembled Bilirubin/V9302 Nanoparticles for Psoriasis Treatment , 2023, Advanced healthcare materials.

[3]  M. Barańska,et al.  What is the ability of inflamed endothelium to uptake exogenous saturated fatty acids? A proof-of-concept study using spontaneous Raman, SRS and CARS microscopy , 2022, Cellular and Molecular Life Sciences.

[4]  D. Offen,et al.  Extracellular vesicles over adeno-associated viruses: Advantages and limitations as drug delivery platforms in precision medicine. , 2022, Advanced drug delivery reviews.

[5]  Qian Wang,et al.  Dual-targeting celecoxib nanoparticles protect intestinal epithelium and regulate macrophage polarization for ulcerative colitis treatment , 2022, Chemical Engineering Journal.

[6]  Ruijie Chen,et al.  Alantolactone-loaded chitosan/hyaluronic acid nanoparticles suppress psoriasis by deactivating STAT3 pathway and restricting immune cell recruitment , 2022, Asian journal of pharmaceutical sciences.

[7]  Han Liu,et al.  Punicalagin Alleviates Psoriasis by Inhibiting NF-κB-Mediated IL-1β Transcription and Caspase-1-Regulated IL-1β Secretion , 2022, Frontiers in Pharmacology.

[8]  V. Ganapathy,et al.  Self-assembled nanoparticles with bilirubin/JPH203 alleviate imiquimod-induced psoriasis by reducing oxidative stress and suppressing Th17 expansion , 2021, Chemical Engineering Journal.

[9]  Sommer Aldulaimi,et al.  Splenomegaly: Diagnosis and Management in Adults. , 2021, American family physician.

[10]  Juan Li,et al.  Role of psoriatic keratinocytes in the metabolic reprogramming of dermal mesenchymal stem cells , 2021, International journal of dermatology.

[11]  M. J. Wood,et al.  Extracellular vesicles as a next-generation drug delivery platform , 2021, Nature Nanotechnology.

[12]  V. Ganapathy,et al.  Resetting amino acid metabolism of cancer cells by ATB0,+-targeted nanoparticles for enhanced anticancer therapy , 2021, Bioactive Materials.

[13]  M. Verdier,et al.  Autophagy and Extracellular Vesicles, Connected to rabGTPase Family, Support Aggressiveness in Cancer Stem Cells , 2021, Cells.

[14]  Ying-zheng Zhao,et al.  Hyaluronic acid coated bilirubin nanoparticles attenuate ischemia reperfusion-induced acute kidney injury. , 2021, Journal of controlled release : official journal of the Controlled Release Society.

[15]  J. Travers,et al.  Keratinocyte-derived microvesicle particles mediate Ultraviolet B radiation induced systemic immunosuppression. , 2021, The Journal of clinical investigation.

[16]  M. L. González-Rodríguez,et al.  Preparation and In Vivo Evaluation of Rosmarinic Acid-Loaded Transethosomes After Percutaneous Application on a Psoriasis Animal Model , 2021, AAPS PharmSciTech.

[17]  Y. Ping,et al.  Microneedle-assisted genome editing: A transdermal strategy of targeting NLRP3 by CRISPR-Cas9 for synergistic therapy of inflammatory skin disorders , 2021, Science Advances.

[18]  A. Balato,et al.  Therapeutics targeting the IL-23 and IL-17 pathway in psoriasis , 2021, The Lancet.

[19]  Xiang Chen,et al.  Metabolomic profiling reveals amino acid and carnitine alterations as metabolic signatures in psoriasis , 2021, Theranostics.

[20]  Yong Nie,et al.  Extracellular heme recycling and sharing across species by novel mycomembrane vesicles of a Gram-positive bacterium , 2020, The ISME journal.

[21]  W. Zhou,et al.  GLS1-mediated glutaminolysis unbridled by MALT1 protease promotes psoriasis pathogenesis. , 2020, The Journal of clinical investigation.

[22]  A. Armstrong,et al.  Pathophysiology, Clinical Presentation, and Treatment of Psoriasis: A Review. , 2020, JAMA.

[23]  F. Sánchez‐Madrid,et al.  Metabolic Pathways That Control Skin Homeostasis and Inflammation. , 2020, Trends in molecular medicine.

[24]  R. Schiffelers,et al.  Extracellular vesicles as drug delivery systems: Why and how? , 2020, Advanced drug delivery reviews.

[25]  J. Furuse,et al.  First-in-human phase I study of JPH203, an L-type amino acid transporter 1 inhibitor, in patients with advanced solid tumors , 2020, Investigational New Drugs.

[26]  O. Kaminuma,et al.  LAT1‐specific inhibitor is effective against T cell‐mediated allergic skin inflammation , 2020, Allergy.

[27]  B. Vergani,et al.  Evidence for a role of autoinflammation in early‐phase psoriasis , 2019, Clinical and experimental immunology.

[28]  Jiye Cai,et al.  Chemotherapeutic drugs stimulate the release and recycling of extracellular vesicles to assist cancer cells in developing an urgent chemoresistance , 2019, Molecular Cancer.

[29]  R. Weichselbaum,et al.  A Critical Role of the IL-1β-IL-1R Signaling Pathway in Skin Inflammation and Psoriasis Pathogenesis. , 2019, The Journal of investigative dermatology.

[30]  C. Théry,et al.  Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication , 2019, Nature Cell Biology.

[31]  Minhong Gao,et al.  Rapamycin ameliorates psoriasis by regulating the expression and methylation levels of tropomyosin via ERK1/2 and mTOR pathways in vitro and in vivo , 2018, Experimental dermatology.

[32]  David K. Finlay,et al.  Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice , 2018, Nature Communications.

[33]  R. Deberardinis,et al.  Differential Glucose Requirement in Skin Homeostasis and Injury Identifies a Therapeutic Target for Psoriasis , 2018, Nature Medicine.

[34]  J. Krueger,et al.  Psoriasis pathogenesis and the development of novel targeted immune therapies , 2017, The Journal of allergy and clinical immunology.

[35]  Shao-Cong Sun,et al.  NF-κB signaling in inflammation , 2017, Signal Transduction and Targeted Therapy.

[36]  J. Travers,et al.  UVB‐generated Microvesicle Particles: A Novel Pathway by Which a Skin‐specific Stimulus Could Exert Systemic Effects , 2017, Photochemistry and photobiology.

[37]  N. Monteiro-Riviere,et al.  Mechanisms of cell uptake, inflammatory potential and protein corona effects with gold nanoparticles. , 2016, Nanomedicine.

[38]  Pieter Vader,et al.  Extracellular vesicles for drug delivery. , 2016, Advanced drug delivery reviews.

[39]  F. Sánchez‐Madrid,et al.  CD69 controls the uptake of L-tryptophan through LAT1-CD98 and AhR-dependent secretion of IL-22 in psoriasis , 2016, Nature Immunology.

[40]  S. Chimenti,et al.  Tofacitinib for the treatment of psoriasis , 2016, Expert opinion on pharmacotherapy.

[41]  J. Travers,et al.  UVB Generates Microvesicle Particle Release in Part Due to Platelet‐activating Factor Signaling , 2016, Photochemistry and photobiology.

[42]  K. Reich,et al.  Drug safety of systemic treatments for psoriasis: results from The German Psoriasis Registry PsoBest , 2015, Archives of Dermatological Research.

[43]  M. Suárez-Fariñas,et al.  IL-17 Induces an Expanded Range of Downstream Genes in Reconstituted Human Epidermis Model , 2014, PloS one.

[44]  H. Endou,et al.  LAT1 Is a Critical Transporter of Essential Amino Acids for Immune Reactions in Activated Human T Cells , 2013, The Journal of Immunology.

[45]  David A. Martin,et al.  The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses. , 2013, Trends in immunology.

[46]  Linda V. Sinclair,et al.  Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation , 2013, Nature Immunology.

[47]  Zhonggui He,et al.  The endocytosis and intracellular fate of nanomedicines: Implication for rational design , 2013 .

[48]  D. Jarrossay,et al.  Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β , 2012, Nature.

[49]  H. Sung,et al.  The characteristics, cellular uptake and intracellular trafficking of nanoparticles made of hydrophobically-modified chitosan. , 2010, Journal of controlled release : official journal of the Controlled Release Society.

[50]  L. Boon,et al.  Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice Is Mediated via the IL-23/IL-17 Axis1 , 2009, The Journal of Immunology.

[51]  M. Conese,et al.  Role of clathrin- and caveolae-mediated endocytosis in gene transfer mediated by lipo- and polyplexes. , 2005, Molecular therapy : the journal of the American Society of Gene Therapy.

[52]  R. Stern.  The risk of melanoma in association with long-term exposure to PUVA. , 2001, Journal of the American Academy of Dermatology.

[53]  A. Prescott,et al.  The coated pit and macropinocytic pathways serve distinct endosome populations , 1994, The Journal of cell biology.

[54]  Mark Lebwohl,et al.  Psoriasis , 1906, The Lancet.

[55]  M. Fresno,et al.  Targeting L-type amino acid transporter 1 in innate and adaptive T cells efficiently controls skin inflammation , 2019 .