A patient with lung cancer metastatic to the fifth thoracic vertebra and spinal cord compression treated with percutaneous vertebroplasty and I-125 seed implantation.

Percutaneous vertebroplasty is a minimally invasive surgical technique for the treatment of spinal damage and pathological compression fractures. Iodine-125 (I-125) particles can inhibit the uncontrolled proliferation of tumor cells to achieve anti-tumor effects. We report treating a spinal cord compression and T5 metastatic lung cancer patient through percutaneous vertebroplasty and I-125 seed implantation. Three years of follow-up demonstrated that our surgical plan achieved a satisfactory clinical outcome with good postsurgical recovery of spinal column function and relieved the symptoms of spinal cord compression.

[1]  Ping Jiang,et al.  CT-guided iodine-125 seed permanent implantation for recurrent head and neck cancers , 2010, Radiation oncology.

[2]  F. Waterman,et al.  Localization of linked 125I seeds in postimplant TRUS images for prostate brachytherapy dosimetry. , 2005, International journal of radiation oncology, biology, physics.

[3]  C. Fiandra,et al.  Prostate Brachytherapy with Iodine-125 Seeds: Radiation Protection Issues , 2005, Tumori.

[4]  Min Peng,et al.  [Treating metastatic vertebral tumor with percutaneous vertebroplasty: a report of 28 cases]. , 2005, Ai zheng = Aizheng = Chinese journal of cancer.

[5]  C. Qian Interstitial ~(125)I implants for liver malignancies , 2005 .

[6]  Janet E Brown,et al.  Metastatic Bone Disease , 2003 .

[7]  P. N. Scutellari,et al.  [Metastatic bone disease. Strategies for imaging]. , 2003, Minerva medica.

[8]  S. Weiner Metastatic bone disease. , 2002, Orthopedics.

[9]  M Maghsudi,et al.  Surgical management of symptomatic spinal metastases. Postoperative outcome and quality of life. , 1999, Spine.

[10]  M. Chamberlain,et al.  Epidural spinal cord compression: a single institution's retrospective experience. , 1999, Neuro-oncology.

[11]  J. Chiras,et al.  Spinal metastases: indications for and results of percutaneous injection of acrylic surgical cement. , 1996, Radiology.

[12]  M. A. Wilson,et al.  The distribution of skeletal metastases in breast and pulmonary cancer: concise communication. , 1981, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[13]  M. Francis,et al.  Correlation of neoplasms with incidence and localization of skeletal metastases: An analysis of 1,355 diphosphonate bone scans. , 1975, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.