Operative management of choanal atresia: a 15-year experience.

OBJECTIVE To analyze factors affecting 15-year surgical outcomes of choanal atresia repair. DESIGN Case series. SETTING Tertiary care pediatric hospital. PATIENTS Between April 17, 1996, and March 23, 2010, a total of 42 patients aged 3 days to 15 years underwent endoscopic or transpalatal choanal atresia repair by our pediatric otolaryngology faculty. MAIN OUTCOME MEASURES Reoperation and restenosis rates, with consideration of effects of mitomycin C therapy, stenting, and postoperative dilation. RESULTS Three of 42 patients were excluded because of inadequate follow-up data; the follow-up time for the remaining 39 patients averaged 6.3 years (range, 1-14.9 years). Excluding 6 patients whose initial repair was performed by other physicians, 31 of 33 patients in whom we performed initial repair had a total of 43 endoscopic surgical procedures (19 patients had unilateral procedures, and 12 patients had bilateral procedures), and the other 2 underwent bilateral transpalatal repair. Of the total 43 sides we operated on endoscopically, 9 sides (21%) required revision surgery, including excision of scar tissue or additional drilling of persistent bony stenosis. No significant difference was observed in the rate of restenosis among cases treated endoscopically with mitomycin C (22 of 43 operative sides, P = .13), with stenting (36 of 43 operative sides, P = .99), or with subsequent dilation (P = .45). When we used stents, they were usually (in 28 of 36 patients) left in place for 15 days or longer. CONCLUSION Our revision rate after initial endoscopic repair of choanal atresia was low and was unaffected by adjuvant mitomycin C therapy or stenting.

[1]  V. Uzomefuna,et al.  Transnasal endoscopic repair of choanal atresia in a tertiary care centre: a review of outcomes. , 2012, International journal of pediatric otorhinolaryngology.

[2]  Á. Atallah,et al.  Surgery for congenital choanal atresia. , 2012, The Cochrane database of systematic reviews.

[3]  O. Albirmawy,et al.  A 13-year experience and predictors for success in transnasal endoscopic repair of congenital choanal obliteration. , 2010, International journal of pediatric otorhinolaryngology.

[4]  K. Ozturk,et al.  The use of adjunctive topical mitomycin in endoscopic congenital choanal atresia repair. , 2010, International journal of pediatric otorhinolaryngology.

[5]  M. Elloy,et al.  Refractory choanal atresia: what makes a child susceptible? The great Ormond Street Hospital experience. , 2008, Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale.

[6]  N. Yıldırım,et al.  Transnasal Endoscopic Repair of Choanal Atresia: Results of 13 Cases and Meta-Analysis , 2008, The Journal of craniofacial surgery.

[7]  A. Jeyakumar,et al.  Choanal Atresia: Embryologic Analysis and Evolution of Treatment, a 30‐Year Experience , 2008, The Laryngoscope.

[8]  V. Couloigner,et al.  Predictive factors for success after transnasal endoscopic treatment of choanal atresia. , 2008, Archives of otolaryngology--head & neck surgery.

[9]  W. Mann,et al.  Forty-one cases of congenital choanal atresia over 26 years--retrospective analysis of outcome and technique. , 2007, Rhinology.

[10]  R. Fujita,et al.  Endoscopic transeptal surgery for choanal atresia with a stentless folded-over-flap technique , 2005, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[11]  H. Kubba,et al.  An update on choanal atresia surgery at Great Ormond Street Hospital for Children: preliminary results with Mitomycin C and the KTP laser. , 2004, International journal of pediatric otorhinolaryngology.

[12]  P. Froehlich,et al.  CT-assisted surgery in choanal atresia. , 2004, Acta oto-laryngologica.

[13]  S. Schoem Transnasal Endoscopic Repair of Choanal Atresia: Why Stent? , 2003, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[14]  C. Cantaroni,et al.  Endoscopic treatment of congenital choanal atresia. , 2003, International journal of pediatric otorhinolaryngology.

[15]  M. Francois,et al.  Transnasal endoscopic treatment of choanal atresia without prolonged stenting. , 2002, Archives of otolaryngology--head & neck surgery.

[16]  B. Liktor,et al.  A New Endoscopic Surgical Method for Unilateral Choanal Atresia , 2001, The Laryngoscope.

[17]  N. Friedman,et al.  Management and outcome of choanal atresia correction. , 2000, International journal of pediatric otorhinolaryngology.

[18]  B. Wiatrak Unilateral choanal atresia: initial presentation and endoscopic repair. , 1998, International journal of pediatric otorhinolaryngology.

[19]  R. Marion,et al.  Choanal atresia. , 1995, Pediatrics in review.

[20]  J. Manzione,et al.  Anatomic Findings and Management of Choanal Atresia and the Charge Association , 1988, The Annals of otology, rhinology, and laryngology.

[21]  R. Carpenter,et al.  Correction of congenital choanal atresia in children and adults , 1977, The Laryngoscope.