Advances in mRNA Vaccines for Infectious Diseases
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Hu Shan | H. Shan | Giulietta Maruggi | Giulietta Maruggi | Cuiling Zhang | Junwei Li | Cuiling Zhang | Junwei Li
[1] D. Burgess. RNA stability: Remember your driver , 2012, Nature Reviews Genetics.
[2] C. Heirman,et al. Preclinical evaluation of TriMix and antigen mRNA-based antitumor therapy. , 2012, Cancer research.
[3] Margaret M. Billingsley,et al. Biomaterials for vaccine‐based cancer immunotherapy , 2018, Journal of controlled release : official journal of the Controlled Release Society.
[4] Lisa C. Zaba,et al. Resident and "inflammatory" dendritic cells in human skin. , 2009, The Journal of investigative dermatology.
[5] G. Acsadi,et al. Direct gene transfer into mouse muscle in vivo. , 1990, Science.
[6] G. Rhodes,et al. Self-replicating Semliki Forest virus RNA as recombinant vaccine. , 1994, Vaccine.
[7] Edith Jasny,et al. New Vaccine Technologies to Combat Outbreak Situations , 2018, Front. Immunol..
[8] Hiroki Kato,et al. Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stability. , 2008, Molecular therapy : the journal of the American Society of Gene Therapy.
[9] R. Deering,et al. Nucleic acid vaccines: prospects for non-viral delivery of mRNA vaccines , 2014, Expert opinion on drug delivery.
[10] V. Flamand,et al. Intratumoral Delivery of TriMix mRNA Results in T-cell Activation by Cross-Presenting Dendritic Cells , 2015, Cancer Immunology Research.
[11] P. Gupta,et al. Induction of immune responses and protection in mice against rabies using a self-replicating RNA vaccine encoding rabies virus glycoprotein. , 2009, Veterinary microbiology.
[12] Bernard Verrier,et al. Poly(lactic acid) nanoparticles and cell-penetrating peptide potentiate mRNA-based vaccine expression in dendritic cells triggering their activation. , 2019, Biomaterials.
[13] T. Daemen,et al. Tattoo Delivery of a Semliki Forest Virus-Based Vaccine Encoding Human Papillomavirus E6 and E7 , 2015, Vaccines.
[14] Kimberly J. Hassett,et al. Induction of Robust B Cell Responses after Influenza mRNA Vaccination Is Accompanied by Circulating Hemagglutinin-Specific ICOS+ PD-1+ CXCR3+ T Follicular Helper Cells , 2017, Front. Immunol..
[15] K. Ljungberg,et al. Self-replicating alphavirus RNA vaccines , 2015, Expert review of vaccines.
[16] J. Bryers,et al. Scaffold-mediated delivery for non-viral mRNA vaccines , 2018, Gene Therapy.
[17] Kathryn L. Jones,et al. Long-term storage of DNA-free RNA for use in vaccine studies. , 2007, BioTechniques.
[18] D. Weissman,et al. Administration of nucleoside-modified mRNA encoding broadly neutralizing antibody protects humanized mice from HIV-1 challenge , 2017, Nature Communications.
[19] P. Coulie,et al. Tumour antigens recognized by T lymphocytes: at the core of cancer immunotherapy , 2014, Nature Reviews Cancer.
[20] Sanyog Jain,et al. &egr;‐Poly‐L‐Lysine/plasmid DNA nanoplexes for efficient gene delivery in vivo , 2018, International journal of pharmaceutics.
[21] J. Wilschut,et al. Alphavirus-based vaccines encoding nonstructural proteins of hepatitis C virus induce robust and protective T-cell responses. , 2014, Molecular therapy : the journal of the American Society of Gene Therapy.
[22] Ö. Türeci,et al. Improving mRNA-Based Therapeutic Gene Delivery by Expression-Augmenting 3' UTRs Identified by Cellular Library Screening. , 2019, Molecular therapy : the journal of the American Society of Gene Therapy.
[23] D. Weissman,et al. Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA , 2011, Nucleic acids research.
[24] D. Weissman,et al. In vitro transcription of long RNA containing modified nucleosides. , 2013, Methods in molecular biology.
[25] D. Voss,et al. An mRNA Vaccine Encoding Rabies Virus Glycoprotein Induces Protection against Lethal Infection in Mice and Correlates of Protection in Adult and Newborn Pigs , 2016, PLoS neglected tropical diseases.
[26] A. García-Sastre,et al. A Sendai Virus-Derived RNA Agonist of RIG-I as a Virus Vaccine Adjuvant , 2012, Journal of Virology.
[27] R. Weiss,et al. DNA and mRNA vaccination against allergies , 2018, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.
[28] A. Di Nardo,et al. Plasmacytoid dendritic cells sense skin injury and promote wound healing through type I interferons , 2010, The Journal of experimental medicine.
[29] R. Weiss,et al. N(1)-methylpseudouridine-incorporated mRNA outperforms pseudouridine-incorporated mRNA by providing enhanced protein expression and reduced immunogenicity in mammalian cell lines and mice. , 2015, Journal of controlled release : official journal of the Controlled Release Society.
[30] G. Vanham,et al. Type I IFN counteracts the induction of antigen-specific immune responses by lipid-based delivery of mRNA vaccines. , 2013, Molecular therapy : the journal of the American Society of Gene Therapy.
[31] Özlem Türeci,et al. Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy , 2016, Nature.
[32] H. Liao,et al. Potent immune responses in rhesus macaques induced by nonviral delivery of a self-amplifying RNA vaccine expressing HIV type 1 envelope with a cationic nanoemulsion. , 2015, The Journal of infectious diseases.
[33] Yuhua Wang,et al. Systemic delivery of modified mRNA encoding herpes simplex virus 1 thymidine kinase for targeted cancer gene therapy. , 2013, Molecular therapy : the journal of the American Society of Gene Therapy.
[34] A. Jestin,et al. Biosafety of DNA vaccines: New generation of DNA vectors and current knowledge on the fate of plasmids after injection. , 2010, Vaccine.
[35] D. G. Gibson,et al. Rapidly produced SAM® vaccine against H7N9 influenza is immunogenic in mice , 2013, Emerging Microbes & Infections.
[36] Pedro Romero,et al. Exhaustion of tumor-specific CD8⁺ T cells in metastases from melanoma patients. , 2011, The Journal of clinical investigation.
[37] S. Xiao,et al. Recombination in Vaccine and Circulating Strains of Porcine Reproductive and Respiratory Syndrome Viruses , 2009, Emerging infectious diseases.
[38] Qian Feng,et al. MDA5 Detects the Double-Stranded RNA Replicative Form in Picornavirus-Infected Cells , 2012, Cell Reports.
[39] Kelly Servick,et al. On message. , 2017, Science.
[40] D. Weissman. mRNA transcript therapy , 2015, Expert review of vaccines.
[41] R. Steinman,et al. Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans , 2011, The Journal of experimental medicine.
[42] Rolf Suter,et al. Polyethylenimine-based polyplex delivery of self-replicating RNA vaccines. , 2016, Nanomedicine : nanotechnology, biology, and medicine.
[43] K. Lundstrom. Replicon RNA Viral Vectors as Vaccines , 2016, Vaccines.
[44] I. Hoerr. A successful founder off the beaten path , 2017, Nature Biotechnology.
[45] L. Defrancesco. The 'anti-hype' vaccine , 2017, Nature Biotechnology.
[46] Yi-Ling Lin,et al. Japanese encephalitis virus replicon-based vaccine expressing enterovirus-71 epitope confers dual protection from lethal challenges , 2015, Journal of Biomedical Science.
[47] Justin M. Richner,et al. Cellular and Humoral Immunity Protect against Vaginal Zika Virus Infection in Mice , 2018, Journal of Virology.
[48] R. Langer,et al. mRNA vaccine delivery using lipid nanoparticles. , 2016, Therapeutic delivery.
[49] M. Avci-Adali,et al. In vitro synthesis of modified mRNA for induction of protein expression in human cells. , 2014, Journal of visualized experiments : JoVE.
[50] T. Schlake,et al. A novel, disruptive vaccination technology , 2013, Human vaccines & immunotherapeutics.
[51] A. Raj,et al. Identification of a Natural Viral RNA Motif That Optimizes Sensing of Viral RNA by RIG-I , 2015, mBio.
[52] D. Weissman,et al. Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses , 2018, The Journal of experimental medicine.
[53] C. Mandl,et al. Humoral and Cellular Immune Response to RNA Immunization with Flavivirus Replicons Derived from Tick-Borne Encephalitis Virus , 2005, Journal of Virology.
[54] K. Fiedler,et al. mRNA Cancer Vaccines. , 2016, Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer.
[55] U. Şahin,et al. Self-Amplifying RNA Vaccines Give Equivalent Protection against Influenza to mRNA Vaccines but at Much Lower Doses , 2017, Molecular therapy : the journal of the American Society of Gene Therapy.
[56] F. Zohra,et al. Effective delivery with enhanced translational activity synergistically accelerates mRNA-based transfection. , 2007, Biochemical and biophysical research communications.
[57] Santiago Garcia-Vallvé,et al. Working toward a new NIOSH. , 1996, Nucleic Acids Res..
[58] J. Grooten,et al. Type I Interferons Modulate CD8+ T Cell Immunity to mRNA Vaccines. , 2017, Trends in molecular medicine.
[59] P. Eilers,et al. A phase I/IIa immunotherapy trial of HIV-1-infected patients with Tat, Rev and Nef expressing dendritic cells followed by treatment interruption. , 2012, Clinical immunology.
[60] D. Weissman,et al. Expression kinetics of nucleoside-modified mRNA delivered in lipid nanoparticles to mice by various routes. , 2015, Journal of controlled release : official journal of the Controlled Release Society.
[61] T. Decker,et al. The Yin and Yang of type I interferon activity in bacterial infection , 2005, Nature Reviews Immunology.
[62] J. Ulmer,et al. Recent innovations in mRNA vaccines. , 2016, Current opinion in immunology.
[63] J. Ross,et al. mRNA stability in mammalian cells. , 1995, Microbiological reviews.
[64] D. Weissman,et al. Nucleoside Modified mRNA Vaccines for Infectious Diseases. , 2017, Methods in molecular biology.
[65] M. Tatematsu,et al. Extracellular RNA Sensing by Pattern Recognition Receptors , 2018, Journal of Innate Immunity.
[66] D. Harrich,et al. Kunjin Virus Replicon Vaccine Vectors Induce Protective CD8+ T-Cell Immunity , 2002, Journal of Virology.
[67] Robert Langer,et al. Lipid Nanoparticle Assisted mRNA Delivery for Potent Cancer Immunotherapy. , 2017, Nano letters.
[68] Shubiao Zhang,et al. Toxicity of cationic lipids and cationic polymers in gene delivery. , 2006, Journal of controlled release : official journal of the Controlled Release Society.
[69] J. Rosenecker,et al. Expression of therapeutic proteins after delivery of chemically modified mRNA in mice , 2011, Nature Biotechnology.
[70] Daniel G. Anderson,et al. Silencing or stimulation? siRNA delivery and the immune system. , 2011, Annual review of chemical and biomolecular engineering.
[71] L. Ivashkiv,et al. Regulation of type I interferon responses , 2013, Nature Reviews Immunology.
[72] Florian Krammer,et al. Nucleoside-modified mRNA immunization elicits influenza virus hemagglutinin stalk-specific antibodies , 2018, Nature Communications.
[73] Özlem Türeci,et al. mRNA-based therapeutics — developing a new class of drugs , 2014, Nature Reviews Drug Discovery.
[74] R. Johnston,et al. A tetravalent alphavirus-vector based dengue vaccine provides effective immunity in an early life mouse model. , 2014, Vaccine.
[75] F. Sobrino,et al. RNA immunization can protect mice against foot-and-mouth disease virus. , 2010, Antiviral research.
[76] Ruth Hershberg,et al. Selection on codon bias. , 2008, Annual review of genetics.
[77] R. Waymouth,et al. Enhanced mRNA delivery into lymphocytes enabled by lipid-varied libraries of charge-altering releasable transporters , 2018, Proceedings of the National Academy of Sciences.
[78] H. Schild,et al. Correction: Increased Antigen Presentation Efficiency by Coupling Antigens to MHC Class I Trafficking Signals , 2012, The Journal of Immunology.
[79] Daniel G. Anderson,et al. Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, and Toxoplasma gondii challenges with a single dose , 2016, Proceedings of the National Academy of Sciences.
[80] A. Thess,et al. A development that may evolve into a revolution in medicine: mRNA as the basis for novel, nucleotide-based vaccines and drugs , 2014, Therapeutic advances in vaccines.
[81] R. Koup,et al. Dissociation of skeletal muscle for flow cytometric characterization of immune cells in macaques. , 2015, Journal of immunological methods.
[82] Daniel G. Anderson,et al. Materials for non-viral intracellular delivery of messenger RNA therapeutics. , 2016, Journal of controlled release : official journal of the Controlled Release Society.
[83] A. Webber,et al. Function of 3′ non-coding sequences and stop codon usage in expression of the chloroplast psaB gene in Chlamydomonas reinhardtii , 1996, Plant Molecular Biology.
[84] Isabelle Bassi,et al. Self-replicating Replicon-RNA Delivery to Dendritic Cells by Chitosan-nanoparticles for Translation In Vitro and In Vivo , 2014, Molecular therapy. Nucleic acids.
[85] A. Mondal,et al. The role of follicular helper T cells and the germinal center in HIV-1 gp120 DNA prime and gp120 protein boost vaccination , 2014, Human vaccines & immunotherapeutics.
[86] G. Ebel,et al. An mRNA Vaccine Protects Mice against Multiple Tick-Transmitted Flavivirus Infections , 2018, Cell Reports.
[87] Man Li,et al. Induction of HIV-1 gag specific immune responses by cationic micelles mediated delivery of gag mRNA , 2016, Drug delivery.
[88] T. Schlake,et al. Sequence-engineered mRNA Without Chemical Nucleoside Modifications Enables an Effective Protein Therapy in Large Animals , 2015, Molecular therapy : the journal of the American Society of Gene Therapy.
[89] M. Fotin‐Mleczek,et al. Unmodified mRNA in LNPs constitutes a competitive technology for prophylactic vaccines , 2017, npj Vaccines.
[90] D. Harrich,et al. Kunjin Virus Replicon Vectors for Human Immunodeficiency Virus Vaccine Development , 2003, Journal of Virology.
[91] Jack Cuzick,et al. Preventive therapy for cancer. , 2017, The Lancet. Oncology.
[92] N. Sardesai,et al. Immunotherapy Against HPV16/18 Generates Potent TH1 and Cytotoxic Cellular Immune Responses , 2012, Science Translational Medicine.
[93] D. Weissman,et al. Zika virus protection by a single low dose nucleoside modified mRNA vaccination , 2017, Nature.
[94] A. Oxenius,et al. Regulation of antiviral T cell responses by type I interferons , 2015, Nature Reviews Immunology.
[95] R. Schreiber,et al. Blocking monoclonal antibodies specific for mouse IFN-alpha/beta receptor subunit 1 (IFNAR-1) from mice immunized by in vivo hydrodynamic transfection. , 2006, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.
[96] Thomas Krucker,et al. Nonviral delivery of self-amplifying RNA vaccines , 2012, Proceedings of the National Academy of Sciences.
[97] P. Mason,et al. Induction of Broad-Based Immunity and Protective Efficacy by Self-amplifying mRNA Vaccines Encoding Influenza Virus Hemagglutinin , 2015, Journal of Virology.
[98] M. Fotin‐Mleczek,et al. Self-adjuvanted mRNA vaccines induce local innate immune responses that lead to a potent and boostable adaptive immunity. , 2016, Vaccine.
[99] T. Schlake,et al. Protective efficacy of in vitro synthesized, specific mRNA vaccines against influenza A virus infection , 2012, Nature Biotechnology.
[100] D. Weissman,et al. HPLC purification of in vitro transcribed long RNA. , 2013, Methods in molecular biology.
[101] H. Schild,et al. Increased Antigen Presentation Efficiency by Coupling Antigens to MHC Class I Trafficking Signals1 , 2008, The Journal of Immunology.
[102] D. Curiel,et al. A Sindbis virus mRNA polynucleotide vector achieves prolonged and high level heterologous gene expression in vivo. , 1995, Nucleic acids research.
[103] A. Helwak,et al. High Guanine and Cytosine Content Increases mRNA Levels in Mammalian Cells , 2006, PLoS biology.
[104] M. Murphy,et al. Self-replicative RNA vaccines elicit protection against influenza A virus, respiratory syncytial virus, and a tickborne encephalitis virus. , 2001, The Journal of infectious diseases.
[105] J. Routy,et al. Immunologic activity and safety of autologous HIV RNA-electroporated dendritic cells in HIV-1 infected patients receiving antiretroviral therapy. , 2010, Clinical immunology.
[106] M. Schlee. Master sensors of pathogenic RNA – RIG-I like receptors , 2013, Immunobiology.
[107] Tao Gong,et al. Enhanced intranasal delivery of mRNA vaccine by overcoming the nasal epithelial barrier via intra- and paracellular pathways. , 2016, Journal of controlled release : official journal of the Controlled Release Society.
[108] C. K. Kiya,et al. Immunocastration of goats using anti-gonadotrophin releasing hormone vaccine. , 2018, Theriogenology.
[109] H. Shan,et al. Microneedle Patches as Drug and Vaccine Delivery Platform. , 2017, Current medicinal chemistry.
[110] Wing‐Fu Lai,et al. Design of Polymeric Gene Carriers for Effective Intracellular Delivery. , 2018, Trends in biotechnology.
[111] Seth J. Zost,et al. Contemporary H3N2 influenza viruses have a glycosylation site that alters binding of antibodies elicited by egg-adapted vaccine strains , 2017, Proceedings of the National Academy of Sciences.
[112] U. Şahin,et al. Intranodal vaccination with naked antigen-encoding RNA elicits potent prophylactic and therapeutic antitumoral immunity. , 2010, Cancer research.
[113] D. Voss,et al. A thermostable messenger RNA based vaccine against rabies , 2017, PLoS neglected tropical diseases.
[114] R. Levy,et al. mRNA vaccination with charge-altering releasable transporters elicits human T cell responses and cures established tumors in mice , 2018, Proceedings of the National Academy of Sciences.
[115] S. Bertholet,et al. Self-Amplifying mRNA Vaccines Expressing Multiple Conserved Influenza Antigens Confer Protection against Homologous and Heterosubtypic Viral Challenge , 2016, PloS one.
[116] D. Gallie. The cap and poly(A) tail function synergistically to regulate mRNA translational efficiency. , 1991, Genes & development.
[117] Philip C. Bevilacqua,et al. Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation , 2010, Nucleic acids research.
[118] C. Zurla,et al. Proximity Ligation Assays for In Situ Detection of Innate Immune Activation: Focus on In Vitro-Transcribed mRNA , 2018, Molecular therapy. Nucleic acids.
[119] H. Rammensee,et al. Spontaneous cellular uptake of exogenous messenger RNA in vivo is nucleic acid-specific, saturable and ion dependent , 2007, Gene Therapy.
[120] G. Hartmann,et al. Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5′-diphosphates , 2014, Nature.
[121] V. Volchkova,et al. A Kunjin Replicon Virus-like Particle Vaccine Provides Protection Against Ebola Virus Infection in Nonhuman Primates. , 2015, The Journal of infectious diseases.
[122] Bernard Verrier,et al. Efficient stimulation of HIV-1-specific T cells using dendritic cells electroporated with mRNA encoding autologous HIV-1 Gag and Env proteins. , 2006, Blood.
[123] P. Fechter,et al. Recognition of mRNA cap structures by viral and cellular proteins. , 2005, The Journal of general virology.
[124] Birke Andrea Tews,et al. Self-Replicating RNA , 2016, Methods in molecular biology.
[125] Kenneth Lundstrom,et al. Latest development on RNA-based drugs and vaccines , 2018, Future science OA.
[126] J. Rosenecker,et al. Nanotechnologies in delivery of mRNA therapeutics using nonviral vector-based delivery systems , 2017, Gene Therapy.
[127] Justin M. Richner,et al. Modified mRNA Vaccines Protect against Zika Virus Infection , 2017, Cell.
[128] M. Zeng,et al. T-cell-mediated cross-strain protective immunity elicited by prime-boost vaccination with a live attenuated influenza vaccine. , 2014, International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.
[129] C. Grunwitz,et al. mRNA Cancer Vaccines-Messages that Prevail. , 2017, Current topics in microbiology and immunology.
[130] Gunther Hartmann,et al. Selection of Molecular Structure and Delivery of RNA Oligonucleotides to Activate TLR7 versus TLR8 and to Induce High Amounts of IL-12p70 in Primary Human Monocytes1 , 2009, The Journal of Immunology.
[131] R. Flavell,et al. Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3 , 2001, Nature.
[132] B. Walker,et al. Immunization of HIV-1-Infected Persons With Autologous Dendritic Cells Transfected With mRNA Encoding HIV-1 Gag and Nef: Results of a Randomized, Placebo-Controlled Clinical Trial , 2016, Journal of acquired immune deficiency syndromes.
[133] G. Lenzen,et al. Induction of virus‐specific cytotoxic T lymphocytes in vivo by liposome‐entrapped mRNA , 1993, European journal of immunology.
[134] B. Neyns,et al. Intravenous and intradermal TriMix-dendritic cell therapy results in a broad T-cell response and durable tumor response in a chemorefractory stage IV-M1c melanoma patient , 2012, Cancer Immunology, Immunotherapy.
[135] Kimberly J. Hassett,et al. Preclinical and Clinical Demonstration of Immunogenicity by mRNA Vaccines against H10N8 and H7N9 Influenza Viruses , 2017, Molecular therapy : the journal of the American Society of Gene Therapy.
[136] A. Masuda,et al. Results of a randomized, placebo-controlled clinical trial of famvir for active Meniere’s disease , 2003 .
[137] G. B. Robb,et al. mRNA capping: biological functions and applications , 2016, Nucleic acids research.
[138] J. Bolen,et al. Safety Evaluation of Lipid Nanoparticle–Formulated Modified mRNA in the Sprague-Dawley Rat and Cynomolgus Monkey , 2018, Veterinary pathology.
[139] C. Mandl,et al. A cationic nanoemulsion for the delivery of next-generation RNA vaccines. , 2014, Molecular therapy : the journal of the American Society of Gene Therapy.
[140] Jason C Debasitis,et al. Induction of an IFN-Mediated Antiviral Response by a Self-Amplifying RNA Vaccine: Implications for Vaccine Design , 2017, The Journal of Immunology.
[141] D. Weissman,et al. mRNA Is an Endogenous Ligand for Toll-like Receptor 3* , 2004, Journal of Biological Chemistry.
[142] C. Heirman,et al. Particle-mediated Intravenous Delivery of Antigen mRNA Results in Strong Antigen-specific T-cell Responses Despite the Induction of Type I Interferon. , 2016, Molecular therapy. Nucleic acids.
[143] D. Weissman,et al. mRNA vaccines — a new era in vaccinology , 2018, Nature Reviews Drug Discovery.
[144] S. Buus,et al. Efficient Induction of T Cells against Conserved HIV-1 Regions by Mosaic Vaccines Delivered as Self-Amplifying mRNA , 2018, Molecular therapy. Methods & clinical development.
[145] I. Wilson,et al. A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine , 2017, PLoS pathogens.
[146] R. Schreiber,et al. Blocking monoclonal antibodies specific for mouse IFN-alpha/beta receptor subunit 1 (IFNAR-1) from mice immunized by in vivo hydrodynamic transfection. , 2006, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.
[147] C. D. de Haan,et al. Evaluation of nonspreading Rift Valley fever virus as a vaccine vector using influenza virus hemagglutinin as a model antigen. , 2014, Vaccine.
[148] Yan Zhou,et al. Influenza A Virus Panhandle Structure Is Directly Involved in RIG-I Activation and Interferon Induction , 2015, Journal of Virology.
[149] Timothy B. Stockwell,et al. Reversion of Cold-Adapted Live Attenuated Influenza Vaccine into a Pathogenic Virus , 2016, Journal of Virology.
[150] K. Miller,et al. Self-adjuvanted mRNA vaccination in advanced prostate cancer patients: a first-in-man phase I/IIa study , 2015, Journal of Immunotherapy for Cancer.
[151] Zhaolin Hua,et al. TLR signaling in B-cell development and activation , 2012, Cellular and Molecular Immunology.
[152] T. Fujita,et al. RIG-I-Like Receptors and Type I Interferonopathies. , 2017, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.
[153] M. Kozak. An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs. , 1987, Nucleic acids research.
[154] H. Goossens,et al. Induction of Cytomegalovirus-Specific T Cell Responses in Healthy Volunteers and Allogeneic Stem Cell Recipients Using Vaccination With Messenger RNA–Transfected Dendritic Cells , 2014, Transplantation.
[155] Shizuo Akira,et al. Signaling to NF-?B by Toll-like receptors , 2007 .
[156] U. Şahin,et al. Modification of antigen-encoding RNA increases stability, translational efficacy, and T-cell stimulatory capacity of dendritic cells. , 2006, Blood.
[157] R. Gottardo,et al. Safety and immunogenicity of a mRNA rabies vaccine in healthy adults: an open-label, non-randomised, prospective, first-in-human phase 1 clinical trial , 2017, The Lancet.
[158] Holger Laux,et al. Expression of the human cytomegalovirus pentamer complex for vaccine use in a CHO system , 2015, Biotechnology and bioengineering.
[159] Michele A. Kutzler,et al. DNA vaccines: ready for prime time? , 2008, Nature Reviews Genetics.
[160] T. Schlake,et al. Developing mRNA-vaccine technologies , 2012, RNA biology.
[161] A. Cascante,et al. mRNA Delivery System for Targeting Antigen‐Presenting Cells In Vivo , 2018, Advanced healthcare materials.
[162] C. Mandl,et al. RNA: the new revolution in nucleic acid vaccines. , 2013, Seminars in immunology.
[163] S. Pascolo. Vaccination with messenger RNA. , 2006, Methods in molecular medicine.
[164] Olga Yuzhakov,et al. Modified mRNA-Based Vaccines Elicit Robust Immune Responses and Protect Guinea Pigs From Ebola Virus Disease , 2018, The Journal of infectious diseases.
[165] G. Bensi,et al. Immunogenicity and protective efficacy induced by self-amplifying mRNA vaccines encoding bacterial antigens. , 2017, Vaccine.
[166] C. Rudolph,et al. Maximizing the Translational Yield of mRNA Therapeutics by Minimizing 5'-UTRs. , 2019, Tissue engineering. Part A.
[167] C. Reis e Sousa,et al. Cytosolic Sensing of Viruses , 2013, Immunity.
[168] D. Weissman,et al. Increased Erythropoiesis in Mice Injected With Submicrogram Quantities of Pseudouridine-containing mRNA Encoding Erythropoietin , 2012, Molecular therapy : the journal of the American Society of Gene Therapy.
[169] R. Steinman,et al. Dendritic cells and the control of immunity , 1998, Nature.
[170] Nicole C. Robb,et al. RIG-I Detects Viral Genomic RNA during Negative-Strand RNA Virus Infection , 2010, Cell.
[171] F. Scorza,et al. New Kids on the Block: RNA-Based Influenza Virus Vaccines , 2018, Vaccines.
[172] J. Ulmer,et al. Mechanism of action of mRNA-based vaccines , 2017, Expert review of vaccines.