Robust stability of stochastic genetic regulatory networks with discrete and distributed delays

In this paper, the problem on asymptotical and robust stability of genetic regulatory networks with time-varying delays and stochastic disturbance is considered. The time-varying delays include not only discrete delays but also distributed delays. The parameter uncertainties are time-varying and norm-bounded. Based on the Lyapunov stability theory and Lur’s system approach, sufficient conditions are given to ensure the stability of genetic regulatory networks. All the stability conditions are given in terms of linear matrix inequalities, which are easy to be verified. Illustrative example is presented to show the effectiveness of the obtained results.

[1]  B. Øksendal Stochastic Differential Equations , 1985 .

[2]  Stephen P. Boyd,et al.  Linear Matrix Inequalities in Systems and Control Theory , 1994 .

[3]  Vladimir A. Yakubovich,et al.  Linear Matrix Inequalities in System and Control Theory (S. Boyd, L. E. Ghaoui, E. Feron, and V. Balakrishnan) , 1995, SIAM Rev..

[4]  E. Yaz Linear Matrix Inequalities In System And Control Theory , 1998, Proceedings of the IEEE.

[5]  E. Davidson,et al.  Genomic cis-regulatory logic: experimental and computational analysis of a sea urchin gene. , 1998, Science.

[6]  K. Gu An integral inequality in the stability problem of time-delay systems , 2000, Proceedings of the 39th IEEE Conference on Decision and Control (Cat. No.00CH37187).

[7]  M. Elowitz,et al.  A synthetic oscillatory network of transcriptional regulators , 2000, Nature.

[8]  L. Serrano,et al.  Engineering stability in gene networks by autoregulation , 2000, Nature.

[9]  D. A. Baxter,et al.  Mathematical Modeling of Gene Networks , 2000, Neuron.

[10]  Guanrong Chen,et al.  Novel robust stability criteria for interval-delayed Hopfield neural networks , 2001 .

[11]  Farren J. Isaacs,et al.  Computational studies of gene regulatory networks: in numero molecular biology , 2001, Nature Reviews Genetics.

[12]  E. Davidson,et al.  Modeling transcriptional regulatory networks. , 2002, BioEssays : news and reviews in molecular, cellular and developmental biology.

[13]  Hidde de Jong,et al.  Modeling and Simulation of Genetic Regulatory Systems: A Literature Review , 2002, J. Comput. Biol..

[14]  K. Aihara,et al.  Stability of genetic regulatory networks with time delay , 2002 .

[15]  Guanrong Chen,et al.  LMI-based approach for asymptotically stability analysis of delayed neural networks , 2002 .

[16]  Kazuyuki Aihara,et al.  Modeling genetic switches with positive feedback loops. , 2003, Journal of theoretical biology.

[17]  Ruiqi Wang,et al.  Modelling periodic oscillation of biological systems with multiple timescale networks. , 2004, Systems biology.

[18]  Kevin Burrage,et al.  Stochastic approaches for modelling in vivo reactions , 2004, Comput. Biol. Chem..

[19]  Chuandong Li,et al.  An LMI approach to asymptotical stability of multi-delayed neural networks , 2005 .

[20]  Chuandong Li,et al.  New Exponential Stability Criteria for Delayed Neural Networks , 2005, 2005 International Conference on Neural Networks and Brain.

[21]  Xuyang Lou,et al.  On the global robust asymptotic stability of BAM neural networks with time-varying delays , 2006, Neurocomputing.

[22]  Chuandong Li,et al.  Delay-Dependent and Delay-Independent Stability Criteria for Cellular Neural Networks with Delays , 2006, Int. J. Bifurc. Chaos.

[23]  Zidong Wang,et al.  Robust stability for stochastic Hopfield neural networks with time delays , 2006 .

[24]  K. Aihara,et al.  Synchronization of coupled nonidentical genetic oscillators , 2006, Physical biology.

[25]  Kazuyuki Aihara,et al.  Stability of Genetic Networks With SUM Regulatory Logic: Lur'e System and LMI Approach , 2006, IEEE Transactions on Circuits and Systems I: Regular Papers.

[26]  P. Shi,et al.  Novel robust stability criteria for uncertain stochastic Hopfield neural networks with time-varying delays , 2007 .

[27]  Zidong Wang,et al.  Exponential stability of uncertain stochastic neural networks with mixed time-delays , 2007 .

[28]  G. Feng,et al.  Delay-dependent stability for uncertain stochastic neural networks with time-varying delay , 2007 .

[29]  Jinde Cao,et al.  Asymptotic and robust stability of genetic regulatory networks with time-varying delays , 2008, Neurocomputing.

[30]  Jinde Cao,et al.  Exponential Stability of Discrete-Time Genetic Regulatory Networks With Delays , 2008, IEEE Transactions on Neural Networks.