Breast elastography: A literature review.

Breast elastography is a new sonographic imaging technique which provides information on breast lesions in addition to conventional ultrasonography (US) and mammography. Elastography provides a noninvasive evaluation of the stiffness of a lesion. Today, two technical solutions are available for clinical use: strain elastography and shear wave elastography. Initial evaluations of these techniques in clinical trials suggest that they may substantially improve the possibility of differentiating benign from malignant breast lesions thereby limiting recourse to biopsy and considerably reducing the number of benign breast biopsy diagnoses. This article reviews the basics of this technique, how to perform the examination, image interpretation and the results of major clinical studies. Although elastography is easy to perform, training and technical knowledge are required in order to obtain images permitting a correct interpretation. This paper will highlight the technique and point out common pitfalls. Breast elastography is a new sonographic imaging technique which provides information on breast lesions in addition to conventional ultrasonography (US) and mammography. Elastography provides a noninvasive evaluation of the stiffness of a lesion. Today, two technical solutions are available for clinical use: strain elastography and shear wave elastography. Initial evaluations of these techniques in clinical trials suggest that they may substantially improve the possibility of differentiating benign from malignant breast lesions thereby limiting recourse to biopsy and considerably reducing the number of benign breast biopsy diagnoses. This article reviews the basics of this technique, how to perform the examination, image interpretation and the results of major clinical studies. Although elastography is easy to perform, training and technical knowledge are required in order to obtain images permitting a correct interpretation. This paper will highlight the technique and point out common pitfalls.

[1]  W. O’Brien,et al.  Young's modulus measurements of soft tissues with application to elasticity imaging , 1996, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[2]  Michael F. Insana,et al.  Viscoelastic Imaging of Breast Tumor Microenvironment With Ultrasound , 2004, Journal of Mammary Gland Biology and Neoplasia.

[3]  Kenneth Hoyt,et al.  Real-time shear velocity imaging using sonoelastographic techniques. , 2007, Ultrasound in medicine & biology.

[4]  Hui Zhi,et al.  Comparison of Ultrasound Elastography, Mammography, and Sonography in the Diagnosis of Solid Breast Lesions , 2007, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[5]  Tatsuya Higashi,et al.  Cervical lymph node metastases: diagnosis at sonoelastography--initial experience. , 2007, Radiology.

[6]  T. Yılmaz,et al.  Qualitative and Semiquantitative Evaluations of Solid Breast Lesions by Sonoelastography , 2011, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[7]  G. Farr,et al.  Benign Diagnosis by Image-Guided Core-Needle Breast Biopsy , 2000, The American surgeon.

[8]  T. Matsumura,et al.  Breast disease: clinical application of US elastography for diagnosis. , 2006, Radiology.

[9]  Woo Kyung Moon,et al.  Sonoelastographic Strain Index for Differentiation of Benign and Malignant Nonpalpable Breast Masses , 2010, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[10]  Jorma Isola,et al.  The effect of age and density of the breast on the sensitivity of breast cancer diagnostic by mammography and ultasonography , 2001, Breast Cancer Research and Treatment.

[11]  M. Fink,et al.  Breast lesions: quantitative elastography with supersonic shear imaging--preliminary results. , 2010, Radiology.

[12]  Mickael Tanter,et al.  Multiwave imaging and super resolution , 2010 .

[13]  M. Fink,et al.  Supersonic shear imaging: a new technique for soft tissue elasticity mapping , 2004, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[14]  Tsuyoshi Shiina,et al.  Real time tissue elasticity imaging using the combined autocorrelation method , 2002, Journal of Medical Ultrasonics.

[15]  Kim Thomson,et al.  Quantitative shear wave ultrasound elastography: initial experience in solid breast masses , 2010, Breast Cancer Research.

[16]  Helmut Ermert,et al.  Initial experiences with real-time elastography guided biopsies of the prostate. , 2005, The Journal of urology.

[17]  G. Trahey,et al.  Acoustic radiation force impulse imaging: remote palpation of the mechanical properties of tissue , 2002, 2002 IEEE Ultrasonics Symposium, 2002. Proceedings..

[18]  T. Miyagawa,et al.  Real-time elastography for the diagnosis of prostate cancer: evaluation of elastographic moving images. , 2009, Japanese journal of clinical oncology.

[19]  Min Bai,et al.  Virtual Touch Tissue Quantification Using Acoustic Radiation Force Impulse Technology , 2012, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[20]  Thomas Deffieux,et al.  Quantitative assessment of breast lesion viscoelasticity: initial clinical results using supersonic shear imaging. , 2008, Ultrasound in medicine & biology.

[21]  A. Goddi,et al.  Real-time tissue elastography for testicular lesion assessment , 2011, European Radiology.

[22]  Gregg Trahey,et al.  Observations of Tissue Response to Acoustic Radiation Force: Opportunities for Imaging , 2002, Ultrasonic imaging.

[23]  F. S. Vinson,et al.  A pulsed Doppler ultrasonic system for making noninvasive measurements of the mechanical properties of soft tissue. , 1987, Journal of rehabilitation research and development.

[24]  Richard G Barr,et al.  Shear Wave Imaging of the Breast , 2012, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[25]  F. Aigner,et al.  Real-time sonoelastography for the evaluation of testicular lesions. , 2012, Radiology.

[26]  G. Bartsch,et al.  Comparison of sonoelastography guided biopsy with systematic biopsy: impact on prostate cancer detection , 2007, European Radiology.

[27]  L. Liberman,et al.  Breast imaging reporting and data system (BI-RADS). , 2002, Radiologic clinics of North America.

[28]  Margaret M Szabunio,et al.  Elastography for the characterization of breast lesions: initial clinical experience. , 2010, Cancer control : journal of the Moffitt Cancer Center.

[29]  T. Krouskop,et al.  Elastic Moduli of Breast and Prostate Tissues under Compression , 1998, Ultrasonic imaging.

[30]  Sachiko Isobe,et al.  Ultrasonographic elastography of the breast using acoustic radiation force impulse technology: preliminary study , 2011, Japanese Journal of Radiology.

[31]  A. Martegani,et al.  Elastosonography in the diagnosis of the nodular breast lesions: preliminary report. , 2005, La Radiologia medica.

[32]  Corinne Balleyguier,et al.  Evaluation of Breast Lesions Using Sonographic Elasticity Imaging , 2012, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[33]  Benjamin Castaneda,et al.  US elastography of breast and prostate lesions. , 2009, Radiographics : a review publication of the Radiological Society of North America, Inc.

[34]  Y. Chou,et al.  Sonographic features of nonpalpable breast cancer: a study based on ultrasound-guided wire-localized surgical biopsies. , 2006, Ultrasound in medicine & biology.

[35]  A. Goddi,et al.  Transrectal real-time elastography of the prostate: Normal patterns. , 2011, Journal of ultrasound.

[36]  J. Ophir,et al.  Elastography: A Quantitative Method for Imaging the Elasticity of Biological Tissues , 1991, Ultrasonic imaging.

[37]  H. Frey.  [Realtime elastography. A new ultrasound procedure for the reconstruction of tissue elasticity]. , 2003, Der Radiologe.

[38]  K. Togashi,et al.  Thyroid gland tumor diagnosis at US elastography. , 2005, Radiology.

[39]  Yan Song,et al.  Preliminary results of acoustic radiation force impulse (ARFI) ultrasound imaging of breast lesions. , 2011, Ultrasound in medicine & biology.

[40]  Gregg E. Trahey,et al.  Acoustic radiation force impulse imaging: ex vivo and in vivo demonstration of transient shear wave propagation , 2002, Proceedings IEEE International Symposium on Biomedical Imaging.

[41]  G. Trahey,et al.  In vivo demonstration of acoustic radiation force impulse (ARFI) imaging in the thyroid, abdomen, and breast , 2001, 2001 IEEE Ultrasonics Symposium. Proceedings. An International Symposium (Cat. No.01CH37263).

[42]  J. Radolf,et al.  Bull’s eye: Unraveling the medical mystery of Lyme disease , 2004 .

[43]  Amanda E Lackey,et al.  The Utility of the "Bull's-Eye" Artifact on Breast Elasticity Imaging in Reducing Breast Lesion Biopsy Rate , 2011, Ultrasound quarterly.

[44]  Peter Devilee,et al.  Pathology and Genetics of Tumours of the Breast and Female Genital Organs , 2003 .

[45]  Differentiation of benign from malignant nonpalpable breast masses: A comparison of computer-assisted quantification and visual assessment of lesion stiffness with the use of sonographic elastography , 2010, Acta radiologica.

[46]  Gregg E. Trahey,et al.  Acoustic radiation force impulse imaging of in vivo breast masses , 2004 .

[47]  Sachiko Isobe,et al.  Preliminary study of ultrasonographic tissue quantification of the breast using the acoustic radiation force impulse (ARFI) technology. , 2011, European journal of radiology.

[48]  M. Tozaki,et al.  Pattern classification of ShearWaveTM Elastography images for differential diagnosis between benign and malignant solid breast masses , 2011, Acta radiologica.

[49]  Sebastian Wojcinski,et al.  Significant differentiation of focal breast lesions: calculation of strain ratio in breast sonoelastography. , 2010, Academic radiology.