Identification of the Role of Endogenous Cannabinoids in Pain Modulation: Strategies and Pitfalls
暂无分享,去创建一个
[1] J. Walker,et al. Pain modulation by release of the endogenous cannabinoid anandamide. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[2] M. Herkenham,et al. Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[3] H. Steiner,et al. Altered gene expression in striatal projection neurons in CB1 cannabinoid receptor knockout mice. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[4] D. Kendall,et al. Involvement of the Carboxyl Terminus of the Third Intracellular Loop of the Cannabinoid CB1 Receptor in Constitutive Activation of Gs , 1999, Journal of neurochemistry.
[5] P. Casellas,et al. Cannabinoid receptor CB1 activates the Na+/H+ exchanger NHE‐1 isoform via Gi‐mediated mitogen activated protein kinase signaling transduction pathways , 1999, FEBS letters.
[6] R. Bukoski,et al. A role for N-arachidonylethanolamine (anandamide) as the mediator of sensory nerve-dependent Ca2+-induced relaxation. , 1999, The Journal of pharmacology and experimental therapeutics.
[7] J. Cheer,et al. Modification of 5-HT2 receptor mediated behaviour in the rat by oleamide and the role of cannabinoid receptors , 1999, Neuropharmacology.
[8] P. Casellas,et al. Gi protein modulation induced by a selective inverse agonist for the peripheral cannabinoid receptor CB2: implication for intracellular signalization cross-regulation. , 1999, Molecular pharmacology.
[9] P. Casellas,et al. SR 144528, an antagonist for the peripheral cannabinoid receptor that behaves as an inverse agonist. , 1999, The Journal of pharmacology and experimental therapeutics.
[10] M. Parmentier,et al. Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice. , 1999, Science.
[11] B. Szabo,et al. Effect of the cannabinoid receptor agonist WIN55212‐2 on sympathetic cardiovascular regulation , 1999, British journal of pharmacology.
[12] S. L. Patrick,et al. Evidence for a role of endogenous cannabinoids in the modulation of acute and tonic pain sensitivity , 1998, Brain Research.
[13] F. Fonseca,et al. Role of the Endogenous Cannabinoid System in the Regulation of Motor Activity , 1998, Neurobiology of Disease.
[14] S. Ikeda,et al. SR 141716A acts as an inverse agonist to increase neuronal voltage-dependent Ca2+ currents by reversal of tonic CB1 cannabinoid receptor activity. , 1998, Molecular pharmacology.
[15] A. Makriyannis,et al. Effects of cannabinoids on prolactin and gonadotrophin secretion: involvement of changes in hypothalamic gamma-aminobutyric acid (GABA) inputs. , 1998, Biochemical pharmacology.
[16] A. Urtti,et al. Effect of the CB1 receptor antagonist, SR141716A, on cannabinoid-induced ocular hypotension in normotensive rabbits. , 1998, Life sciences.
[17] R. Beninger,et al. The cannabinoid CB1 receptor antagonist SR141716A attenuates the memory impairment produced by Δ9-tetrahydrocannabinol or anandamide , 1998, Psychopharmacology.
[18] G. Gessa,et al. Inhibition of hippocampal acetylcholine release after acute and repeated Δ9-tetrahydrocannabinol in rats , 1998, Brain Research.
[19] Richard E. White,et al. The actions of the cannabinoid receptor antagonist, SR 141716A, in the rat isolated mesenteric artery , 1998, British journal of pharmacology.
[20] H. Fields,et al. An analgesia circuit activated by cannabinoids , 1998, Nature.
[21] M. Shen,et al. Cannabinoid receptor agonists protect cultured rat hippocampal neurons from excitotoxicity. , 1998, Molecular pharmacology.
[22] G. Gessa,et al. Cannabinoids decrease acetylcholine release in the medial-prefrontal cortex and hippocampus, reversal by SR 141716A. , 1998, European journal of pharmacology.
[23] C. Guaza,et al. The endogenous cannabinoid anandamide potentiates interleukin‐6 production by astrocytes infected with Theiler's murine encephalomyelitis virus by a receptor‐mediated pathway , 1998, FEBS letters.
[24] J. Mogil,et al. Transgenic studies of pain , 1998, Pain.
[25] P. Soubrié,et al. Cannabinoids decrease excitatory synaptic transmission and impair long‐term depression in rat cerebellar Purkinje cells , 1998, The Journal of physiology.
[26] F. Borrelli,et al. Excitatory transmission to the circular muscle of the guinea‐pig ileum: evidence for the involvement of cannabinoid CB1 receptors , 1998, British journal of pharmacology.
[27] G. Kunos,et al. Platelet‐ and macrophage‐derived endogenous cannabinoids are involved in endotoxin‐induced hypotension , 1998, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[28] G. Gessa,et al. Appetite suppression and weight loss after the cannabinoid antagonist SR 141716. , 1998, Life sciences.
[29] D. Piomelli,et al. Control of pain initiation by endogenous cannabinoids , 1998, Nature.
[30] W. Yung,et al. Occlusion of the presynaptic action of cannabinoids in rat substantia nigra pars reticulata by cadmium , 1998, Neuroscience Letters.
[31] D. Bonhaus,et al. Evidence for inverse agonism of SR141716A at human recombinant cannabinoid CB1 and CB2 receptors , 1998, British journal of pharmacology.
[32] G. Gessa,et al. Δ9‐Tetrahydrocannabinol increases sequence‐specific AP‐1 DNA‐binding activity and Fos‐related antigens in the rat brain , 1998, The European journal of neuroscience.
[33] J. Lowe,et al. Characterization of Δ9-Tetrahydrocannabinol and Anandamide Antinociception in Nonarthritic and Arthritic Rats , 1998, Pharmacology Biochemistry and Behavior.
[34] K. Starke,et al. Inhibition of GABAergic inhibitory postsynaptic currents by cannabinoids in rat corpus striatum , 1998, Neuroscience.
[35] J. D. Richardson,et al. Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors , 1998, Pain.
[36] G. Gessa,et al. Cannabinoid modulation of intestinal propulsion in mice. , 1998, European journal of pharmacology.
[37] P. Casellas,et al. SR 144528, the first potent and selective antagonist of the CB2 cannabinoid receptor. , 1998, The Journal of pharmacology and experimental therapeutics.
[38] M. Scanziani,et al. Dual Effects of Anandamide on NMDA Receptor‐Mediated Responses and Neurotransmission , 1998, Journal of neurochemistry.
[39] J. Zentner,et al. Cannabinoid CB1 receptor-mediated inhibition of noradrenaline release in the human and guinea-pig hippocampus Naunyn-Schmiedeberg’s Arch Pharmacol (1997) 356:583–589 , 1998, Naunyn-Schmiedeberg's Archives of Pharmacology.
[40] G. Gessa,et al. Cannabinoids activate mesolimbic dopamine neurons by an action on cannabinoid CB1 receptors. , 1998, European journal of pharmacology.
[41] J. D. Richardson,et al. Hypoactivity of the Spinal Cannabinoid System Results in NMDA-Dependent Hyperalgesia , 1998, The Journal of Neuroscience.
[42] J. Ramos,et al. The activation of cannabinoid receptors in striatonigral GABAergic neurons inhibited GABA uptake. , 1997, Life sciences.
[43] D. Piomelli,et al. Inhibition of intestinal motility by anandamide, an endogenous cannabinoid. , 1997, European journal of pharmacology.
[44] Richard P. White,et al. A comparison of EDHF‐mediated and anandamide‐induced relaxations in the rat isolated mesenteric artery , 1997, British journal of pharmacology.
[45] P. Sacerdote,et al. Regulation of immune functions in rat splenocytes after acute and chronic in vivo treatment with CP-55,940, a synthetic cannabinoid compound , 1997, Journal of Neuroimmunology.
[46] F. Petitet,et al. Interaction of brain cannabinoid receptors with guanine nucleotide binding protein: a radioligand binding study. , 1997, Biochemical pharmacology.
[47] D. R. Compton,et al. The effect of the enzyme inhibitor phenylmethylsulfonyl fluoride on the pharmacological effect of anandamide in the mouse model of cannabimimetic activity. , 1997, The Journal of pharmacology and experimental therapeutics.
[48] C. Hiley,et al. Endothelium and cannabinoid receptor involvement in levcromakalim vasorelaxation. , 1997, European journal of pharmacology.
[49] J. Brotchie,et al. The Cannabinoid Receptor Agonist WIN 55,212-2 Reduces D2, but Not D1, Dopamine Receptor-Mediated Alleviation of Akinesia in the Reserpine-Treated Rat Model of Parkinson's Disease , 1997, Experimental Neurology.
[50] J. Zentner,et al. Cannabinoid CB1 receptor-mediated inhibition of noradrenaline release in the human and guinea-pig hippocampus , 1997, Naunyn-Schmiedeberg's Archives of Pharmacology.
[51] I. Yamamoto,et al. Is the cannabinoid CB1 receptor a 2-arachidonoylglycerol receptor? Structural requirements for triggering a Ca2+ transient in NG108-15 cells. , 1997, Journal of biochemistry.
[52] H. Yamamura,et al. SR141716A is an inverse agonist at the human cannabinoid CB1 receptor. , 1997, European journal of pharmacology.
[53] R. Pertwee,et al. Effects of cannabinoid receptor ligands on electrophysiological properties of myenteric neurones of the guinea‐pig ileum , 1997, British journal of pharmacology.
[54] J. Brodkin,et al. SR141716A antagonizes the disruptive effects of cannabinoid ligands on learning in rats. , 1997, The Journal of pharmacology and experimental therapeutics.
[55] P. Casellas,et al. A Selective Inverse Agonist for Central Cannabinoid Receptor Inhibits Mitogen-activated Protein Kinase Activation Stimulated by Insulin or Insulin-like Growth Factor 1 , 1997, The Journal of Biological Chemistry.
[56] G. Velasco,et al. Δ 9-Tetrahydrocannabinol stimulates glucose utilization in C6 glioma cells , 1997, Brain Research.
[57] T. Wenger,et al. Arachidonyl ethanolamide (anandamide) activates the parvocellular part of hypothalamic paraventricular nucleus. , 1997, Biochemical and biophysical research communications.
[58] R. Pertwee,et al. Inhibition by cannabinoid receptor agonists of acetylcholine release from the guinea‐pig myenteric plexus , 1997, British journal of pharmacology.
[59] B. Malinowska,et al. Cannabinoid CB1 receptor-mediated inhibition of the neurogenic vasopressor response in the pithed rat , 1997, Naunyn-Schmiedeberg's Archives of Pharmacology.
[60] A. Kustka,et al. Morphine- and anadamide-stimulated nitric oxide production inhibits presynaptic dopamine release , 1997, Brain Research.
[61] A. Makriyannis,et al. Time course of the effects of different cannabimimetics on prolactin and gonadotrophin secretion: evidence for the presence of CB1 receptors in hypothalamic structures and their involvement in the effects of cannabimimetics. , 1997, Biochemical pharmacology.
[62] G. Gessa,et al. Inhibition of hippocampal acetylcholine release by cannabinoids: reversal by SR 141716A. , 1997, European journal of pharmacology.
[63] E. French. Δ 9-Tetrahydrocannabinol excites rat VTA dopamine neurons through activation of cannabinoid CB1 but not opioid receptors , 1997, Neuroscience Letters.
[64] G. Kunos,et al. Cardiovascular effects of anandamide in anesthetized and conscious normotensive and hypertensive rats. , 1997, Hypertension.
[65] G. Velasco,et al. Metabolic stimulation of mouse spleen lymphocytes by low doses of delta9-tetrahydrocannabinol. , 1997, Life sciences.
[66] S. Gatley,et al. Examination of the effect of the cannabinoid receptor agonist, CP 55,940, on electrically evoked transmitter release from rat brain slices. , 1997, European journal of pharmacology.
[67] J. Brotchie,et al. Paradoxical action of the cannabinoid WIN 55,212‐2 in stimulated and basal cyclic AMP accumulation in rat globus pallidus slices , 1997, British journal of pharmacology.
[68] S. Burstein,et al. Receptor mediation in cannabinoid stimulated arachidonic acid mobilization and anandamide synthesis. , 1997, Life sciences.
[69] J. D. Richardson,et al. SR 141716A, a cannabinoid receptor antagonist, produces hyperalgesia in untreated mice. , 1997, European journal of pharmacology.
[70] F. Rodríguez de Fonseca,et al. Acute administration of the CB1 cannabinoid receptor antagonist SR 141716A induces anxiety‐like responses in the rat , 1997, Neuroreport.
[71] G. Bennett,et al. The analgesic effects of R(+)-WIN 55,212–2 mesylate, a high affinity cannabinoid agonist, in a rat model of neuropathic pain , 1997, Neuroscience Letters.
[72] P. Soubrié,et al. Characterization of CB1 Receptors on Rat Neuronal Cell Cultures: Binding and Functional Studies Using the Selective Receptor Antagonist SR 141716A , 1997, Journal of neurochemistry.
[73] U. Ungerstedt,et al. Intrastriatally injected c-fos antisense oligonucleotide interferes with striatonigral but not striatopallidal gamma-aminobutyric acid transmission in the conscious rat. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[74] R. Pertwee,et al. Agonist-antagonist characterization of 6'-cyanohex-2'-yne-delta 8-tetrahydrocannabinol in two isolated tissue preparations. , 1996, European journal of pharmacology.
[75] R. E. Brown,et al. Cannabinoid modulation of rat pup ultrasonic vocalizations. , 1996, European journal of pharmacology.
[76] H. Rosenberg,et al. Local pressure application of cannabinoid agonists increases spontaneous activity of rat substantia nigra pars reticulata neurons without affecting response to iontophoretically-applied GABA , 1996, Brain Research.
[77] J. Lowe,et al. Dependence on delta 9-tetrahydrocannabinol: studies on precipitated and abrupt withdrawal. , 1996, The Journal of pharmacology and experimental therapeutics.
[78] G. Kunos,et al. Inhibition of exocytotic noradrenaline release by presynaptic cannabinoid CB 1 receptors on peripheral sympathetic nerves , 1996, British journal of pharmacology.
[79] J. Nash,et al. Further evidence for the presence of cannabinoid CB1 receptors in guinea‐pig small intestine , 1996, British journal of pharmacology.
[80] R. Pertwee,et al. Evidence for the presence of cannabinoid CB1 receptors in mouse urinary bladder , 1996, British journal of pharmacology.
[81] S. Childers,et al. Cannabinoid receptor stimulation of guanosine-5'-O-(3-[35S]thio)triphosphate binding in rat brain membranes. , 1996, Life sciences.
[82] C. Ashby,et al. Electrically evoked acetylcholine release from hippocampal slices is inhibited by the cannabinoid receptor agonist, WIN 55212-2, and is potentiated by the cannabinoid antagonist, SR 141716A. , 1996, The Journal of pharmacology and experimental therapeutics.
[83] J. Lowe,et al. In vivo characterization of a specific cannabinoid receptor antagonist (SR141716A): inhibition of delta 9-tetrahydrocannabinol-induced responses and apparent agonist activity. , 1996, The Journal of pharmacology and experimental therapeutics.
[84] E. Ellis,et al. Anandamide- and delta9-tetrahydrocannabinol-evoked arachidonic acid mobilization and blockade by SR141716A [N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4 -methyl-1H-pyrazole-3-carboximide hydrochloride]. , 1996, Biochemical pharmacology.
[85] R. Knapp,et al. Antisense oligodeoxynucleotide treatment to the brain cannabinoid receptor inhibits antinociception , 1996, Neuroreport.
[86] G. Hawksworth,et al. Further evidence for the presence of cannabinoid CB1 receptors in mouse vas deferens. , 1996, European journal of pharmacology.
[87] T. Chase,et al. Effects of cannabinoid receptor stimulation and blockade on catalepsy produced by dopamine receptor antagonists. , 1996, European journal of pharmacology.
[88] P. Soubrié,et al. Arousal-enhancing properties of the CB1 cannabinoid receptor antagonist SR 141716A in rats as assessed by electroencephalographic spectral and sleep-waking cycle analysis. , 1996, Life sciences.
[89] J. Lowe,et al. Antagonism of the discriminative stimulus effects of delta 9-tetrahydrocannabinol in rats and rhesus monkeys. , 1995, The Journal of pharmacology and experimental therapeutics.
[90] P. Soubrié,et al. The CB1 cannabinoid receptor antagonist SR 141716A affects A9 dopamine neuronal activity in the rat. , 1995, Neuroreport.
[91] C. Destrade,et al. Post-test apamin injection suppresses a Kamin-like effect following a learning session in mice. , 1995, Neuroreport.
[92] P. Casellas,et al. Stimulation of Cannabinoid Receptor CB1 Induces krox-24 Expression in Human Astrocytoma Cells (*) , 1995, The Journal of Biological Chemistry.
[93] B. Martin,et al. Novel antagonist implicates the CB1 cannabinoid receptor in the hypotensive action of anandamide. , 1995, European journal of pharmacology.
[94] P. Soubrié,et al. Biochemical and pharmacological characterisation of SR141716A, the first potent and selective brain cannabinoid receptor antagonist. , 1995, Life sciences.
[95] P. Leff,et al. The two-state model of receptor activation. , 1995, Trends in pharmacological sciences.
[96] P. Soubrié,et al. SR141716A, a potent and selective antagonist of the brain cannabinoid receptor , 1994, FEBS letters.
[97] P. Chidiac,et al. Inverse agonist activity of beta-adrenergic antagonists. , 1994, Molecular pharmacology.
[98] F. Borrelli,et al. Defaecation, intestinal fluid accumulation and motility in rodents: implications of cannabinoid CB1 receptors , 1999, Naunyn-Schmiedeberg's Archives of Pharmacology.
[99] K. Mackie,et al. LY320135, a novel cannabinoid CB1 receptor antagonist, unmasks coupling of the CB1 receptor to stimulation of cAMP accumulation. , 1998, The Journal of pharmacology and experimental therapeutics.
[100] G. Milligan,et al. Inverse agonism: pharmacological curiosity or potential therapeutic strategy? , 1995, Trends in pharmacological sciences.
[101] J. Vivian,et al. Analgesic, Respiratory and Heart Rate Effects of Cannabinoid and Opioid Agonists in Rhesus Monkeys: Antagonist Effects of Sr 141716a 1,2 , 2022 .