Recent pharmacological studies on natural products in China.
暂无分享,去创建一个
Jin Liu | Xiao-yu Li | X. Zhu
[1] M. Beppu,et al. Triptolide, an active compound identified in a traditional Chinese herb, induces apoptosis of rheumatoid synovial fibroblasts , 2004, BMC Pharmacology.
[2] K. Tang,et al. Mechanism of (-)clausenamide induced calcium transient in primary culture of rat cortical neurons. , 2004, Life sciences.
[3] Hualiang Jiang,et al. Progress in clinical, pharmacological, chemical and structural biological studies of huperzine A: a drug of traditional chinese medicine origin for the treatment of Alzheimer's disease. , 2003, Current medicinal chemistry.
[4] Yadi Wu,et al. The suppressive effect of triptolide on experimental autoimmune uveoretinitis by down-regulating Th1-type response. , 2003, International immunopharmacology.
[5] J. A. Ross,et al. PG490-88, a derivative of triptolide, causes tumor regression and sensitizes tumors to chemotherapy. , 2003, Molecular cancer therapeutics.
[6] Xiao-Liang Wang,et al. Effects of chiral 3-n-butylphthalide on apoptosis induced by transient focal cerebral ischemia in rats. , 2003, Acta pharmacologica Sinica.
[7] B. Ahlemeyer,et al. Pharmacological Studies Supporting the Therapeutic Use of Ginkgo biloba Extract for Alzheimer’s Disease , 2003, Pharmacopsychiatry.
[8] A. Zangara. The psychopharmacology of huperzine A: an alkaloid with cognitive enhancing and neuroprotective properties of interest in the treatment of Alzheimer's disease , 2003, Pharmacology Biochemistry and Behavior.
[9] H. Zhang,et al. Huperzine A attenuates the neurotoxic effect of staurosporine in primary rat cortical neurons , 2003, Neuroscience Letters.
[10] Xiao-chao Ma,et al. Acute effects of huperzine A and tacrine on rat liver. , 2003, Acta pharmacologica Sinica.
[11] Xiaochao Ma,et al. Identification of cytochrome P450 1A2 as enzyme involved in the microsomal metabolism of Huperzine A. , 2003, European journal of pharmacology.
[12] Chuan-jiang Zhu,et al. Stereoselective pharmacokinetics of clausenamide enantiomers and their major metabolites after single intravenous and oral administration to rats. , 2003, Chirality.
[13] Chuan-jiang Zhu,et al. Identification of rat cytochrome P450 forms involved in the metabolism of clausenamide enantiomers. , 2003, Chirality.
[14] X. Tang,et al. Effects of huperzine A on acetylcholinesterase isoforms in vitro: comparison with tacrine, donepezil, rivastigmine and physostigmine. , 2002, European journal of pharmacology.
[15] Xiao-yu Li,et al. Ginkgolide A, B, and huperzine A inhibit nitric oxide-induced neurotoxicity. , 2002, International immunopharmacology.
[16] Jin Zhou,et al. Huperzine A attenuates cognitive deficits and brain injury in neonatal rats after hypoxia–ischemia , 2002, Brain Research.
[17] Jin Zhou,et al. Huperzine A attenuates apoptosis and mitochondria‐dependent caspase‐3 in rat cortical neurons , 2002, FEBS letters.
[18] Zhenxin Zhang,et al. [Clinical efficacy and safety of huperzine Alpha in treatment of mild to moderate Alzheimer disease, a placebo-controlled, double-blind, randomized trial]. , 2002, Zhonghua yi xue za zhi.
[19] K. Tang,et al. The effects of (-)clausenamide on functional recovery in transient focal cerebral ischemia , 2002, Neurological research.
[20] Zhi-Hong Liu,et al. Inhibition of vascular endothelial growth factor expression and production by triptolide. , 2002, Planta medica.
[21] D. Bai,et al. Stereoselectivities of enantiomers of huperzine A in protection against β-amyloid25–35-induced injury in PC12 and NG108-15 cells and cholinesterase inhibition in mice , 2002, Neuroscience Letters.
[22] C. Ballard,et al. Advances in the Treatment of Alzheimer’s Disease: Benefits of Dual Cholinesterase Inhibition , 2002, European Neurology.
[23] H. Zhang,et al. Huperzine A attenuates amyloid β‐peptide fragment 25‐35‐induced apoptosis in rat cortical neurons via inhibiting reactive oxygen species formation and caspase‐3 activation , 2002, Journal of neuroscience research.
[24] Yu Fu,et al. (-)-Stepholidine: a potential novel antipsychotic drug with dual D1 receptor agonist and D2 receptor antagonist actions. , 2002, Trends in pharmacological sciences.
[25] J. Cai,et al. Effect of huperzine A on working memory in reserpine- or yohimbine-treated monkeys. , 2001, European journal of pharmacology.
[26] H. Zhang,et al. Huperzine A attenuates cognitive deficits and hippocampal neuronal damage after transient global ischemia in gerbils , 2001, Neuroscience Letters.
[27] T. Sato,et al. Triptolide, a novel diterpenoid triepoxide from Tripterygium wilfordii Hook. f., suppresses the production and gene expression of pro-matrix metalloproteinases 1 and 3 and augments those of tissue inhibitors of metalloproteinases 1 and 2 in human synovial fibroblasts. , 2001, Arthritis and rheumatism.
[28] Z. Liu,et al. [Triptolide inhibits vascular endothelial growth factor expression and production by endothelial cells]. , 2001, Zhonghua yi xue za zhi.
[29] X. Tang,et al. Huperzine A attenuates cognitive dysfunction and neuronal degeneration caused by beta-amyloid protein-(1-40) in rat. , 2001, European journal of pharmacology.
[30] Xu Hl,et al. [Effects of 3-n-butylphthalide on thrombosis formation and platelet function in rats] , 2001 .
[31] J. A. Ross,et al. Triptolide and Chemotherapy Cooperate in Tumor Cell Apoptosis , 2001, The Journal of Biological Chemistry.
[32] G. Berry,et al. Triptolide attenuates pulmonary arterial hypertension and neointimal formation in rats. , 2000, American journal of respiratory and critical care medicine.
[33] K. Goa,et al. Galantamine: a review of its use in Alzheimer's disease. , 2000, Drugs.
[34] P. Kao,et al. Anti-inflammatory effects of triptolide in human bronchial epithelial cells. , 2000, American journal of physiology. Lung cellular and molecular physiology.
[35] F. M. Tang,et al. Relevance between striatal expression of Fos, proenkephalin mRNA, prodynorphin mRNA and rotation induced by l-stepholidine in 6-hydroxydopamine-lesioned rats. , 2000, Acta pharmacologica Sinica.
[36] Rui Wang,et al. Huperzine A and tacrine attenuate β‐amyloid peptide‐induced oxidative injury , 2000 .
[37] G. Hu,et al. Modulation of medical prefrontal cortical D1 receptors on the excitatory firing activity of nucleus accumbens neurons elicited by (-)-Stepholidine. , 2000, Life sciences.
[38] G. Jin,et al. I-stepholidine facilitates inhibition of mPFC DA receptors on subcortical NAc DA release. , 2000, Acta pharmacologica Sinica.
[39] Rui Wang,et al. Protective effects of huperzine A on β-amyloid25–35 induced oxidative injury in rat pheochromocytoma cells , 2000, Neuroscience Letters.
[40] L. Zhou,et al. Reactive oxygen species-induced apoptosis in PC12 cells and protective effect of bilobalide. , 2000, The Journal of pharmacology and experimental therapeutics.
[41] W. Song,et al. Protective effect of bilobalide against nitric oxide-induced neurotoxicity in PC12 cells. , 2000, Acta pharmacologica Sinica.
[42] G. Hu,et al. Electrophysiological study on biphasic firing activity elicited by D(1) agonistic-D(2) antagonistic action of (-)-stepholidine in nucleus accumbens. , 2000, Sheng li xue bao : [Acta physiologica Sinica].
[43] D. Bai,et al. Huperzine A, a potential therapeutic agent for treatment of Alzheimer's disease. , 2000, Current medicinal chemistry.
[44] X. Jie. THE PROTECTIVE EFFECT OF BUTYLPHTHALIDE AGAINST MITOCHONDRIAL INJURY DURING CEREBRAL ISCHEMIA , 2000 .
[45] Jian Yang,et al. Huperzine A protects rat pheochromocytoma cells against hydrogen peroxide-induced injury , 1999, Neuroscience Letters.
[46] H. Xu,et al. Effects of 3-n-butylphthalide on production of vasoactive substances by cerebral and aortic endothelial cells. , 1999, Zhongguo yao li xue bao = Acta pharmacologica Sinica.
[47] J. Kohlmeier,et al. Triptolide is more effective in preventing T cell proliferation and interferon‐gamma production than is FK506 , 1999, Phytotherapy research : PTR.
[48] Y. Feng,et al. dl-3-n-butylphthalide attenuates reperfusion-induced blood-brain barrier damage after focal cerebral ischemia in rats. , 1999, Zhongguo yao li xue bao = Acta pharmacologica Sinica.
[49] H. Koyanagi,et al. Immunosuppressive effect of triptolide in vitro. , 1999, Transplantation proceedings.
[50] Su Qq,et al. Huperzine-A capsules enhance memory and learning performance in 34 pairs of matched adolescent students. , 1999 .
[51] Xing-zu Zhu,et al. Involvement of monoamine oxidase inhibition in neuroprotective and neurorestorative effects of Ginkgo biloba extract against MPTP-induced nigrostriatal dopaminergic toxicity in C57 mice. , 1999, Life sciences.
[52] G. Rosen,et al. PG490 (Triptolide) Cooperates with Tumor Necrosis Factor-α to Induce Apoptosis in Tumor Cells* , 1999, The Journal of Biological Chemistry.
[53] P. Kao,et al. Immunosuppressant PG490 (Triptolide) Inhibits T-cell Interleukin-2 Expression at the Level of Purine-box/Nuclear Factor of Activated T-cells and NF-κB Transcriptional Activation* , 1999, The Journal of Biological Chemistry.
[54] B. Ahlemeyer,et al. Inhibition of serum deprivation- and staurosporine-induced neuronal apoptosis by Ginkgo biloba extract and some of its constituents. , 1999, European journal of pharmacology.
[55] J. Cai,et al. Improving effects of huperzine A on spatial working memory in aged monkeys and young adult monkeys with experimental cognitive impairment. , 1999, The Journal of pharmacology and experimental therapeutics.
[56] Y. Feng,et al. Protective effects of dl-3-n-butylphthalide on changes of regional cerebral blood flow and blood-brain barrier damage following experimental subarachnoid hemorrhage. , 1998, Chinese medical journal.
[57] Y. Yang,et al. Triptolide induces apoptotic death of T lymphocyte. , 1998, Immunopharmacology.
[58] X. Tang,et al. Comparative Studies of Huperzine A, E2020, and Tacrine on Behavior and Cholinesterase Activities , 1998, Pharmacology Biochemistry and Behavior.
[59] C. Yan,et al. [Effects of d-3-n-butylphthalide and l-3-n-butylphthalide on extracellular no level and intracellular cGMP level in primary cultured rat cortical neurons]. , 1998, Yao xue xue bao = Acta pharmaceutica Sinica.
[60] C. Yan,et al. Effects of dl-3-n-butylphthalide on regional cerebral blood flow in right middle cerebral artery occlusion rats. , 1998, Zhongguo yao li xue bao = Acta pharmacologica Sinica.
[61] X. Tang,et al. Anticholinesterase effects of huperzine A, E2020, and tacrine in rats. , 1998, Zhongguo yao li xue bao = Acta pharmacologica Sinica.
[62] J. Zhang,et al. [Effects of (-), (+)clausenamide on anisodine-induced acetylcholine decrease and associated memory deficits in the mouse brain]. , 1998, Yao xue xue bao = Acta pharmaceutica Sinica.
[63] P. Lipsky,et al. Effects of Tripterygium wilfordii hook F extracts on induction of cyclooxygenase 2 activity and prostaglandin E2 production. , 1998, Arthritis and rheumatism.
[64] M. Mesulam,et al. Butyrylcholinesterase in the life cycle of amyloid plaques , 1997, Annals of neurology.
[65] R. Ihl,et al. Clinical efficacy of Ginkgo biloba special extract EGb 761 in dementia of the Alzheimer type. , 1997, Journal of psychiatric research.
[66] H. Hatanaka,et al. Changes in mitochondrial membrane potential during oxidative stress‐induced apoptosis in PC12 cells , 1997, Journal of neuroscience research.
[67] Turan M. Itil,et al. A Placebo-Controlled, Double-blind, Randomized Trial of an Extract of Ginkgo Biloba for Dementia , 1997 .
[68] A. Schatzberg,et al. A placebo-controlled, double-blind, randomized trial of an extract of Ginkgo biloba for dementia. North American EGb Study Group. , 1997, JAMA.
[69] W. Deng,et al. Effect of dl-3-n-butylphthalide on brain edema in rats subjected to focal cerebral ischemia. , 1997, Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih.
[70] D. Butterfield. beta-Amyloid-associated free radical oxidative stress and neurotoxicity: implications for Alzheimer's disease. , 1997, Chemical research in toxicology.
[71] T. Ikeuchi,et al. Generation of free radicals during lipid hydroperoxide-triggered apoptosis in PC12h cells , 1997 .
[72] J. Dave,et al. Huperzine A, a potential therapeutic agent for dementia, reduces neuronal cell death caused by glutamate , 1997, Neuroreport.
[73] J. Pezzuto,et al. Evaluation of the mutagenic, cytotoxic, and antitumor potential of triptolide, a highly oxygenated diterpene isolated from Tripterygium wilfordii. , 1997, Cancer letters.
[74] Y. Jun. Immunosuppression of triptolide on skin allograft in mice , 1997 .
[75] X. Tang,et al. Huperzine A, a novel promising acetylcholinesterase inhibitor , 1996, Neuroreport.
[76] X. Tang. Huperzine A (shuangyiping): a promising drug for Alzheimer's disease. , 1996, Zhongguo yao li xue bao = Acta pharmacologica Sinica.
[77] Paul F. Smith,et al. The neuroprotective properties of the Ginkgo biloba leaf: a review of the possible relationship to platelet-activating factor (PAF). , 1996, Journal of ethnopharmacology.
[78] Y. Feng,et al. [Effect of dl-3-n-butylphthalide (NBP) on life span and neurological deficit in SHRsp rats]. , 1996, Yao xue xue bao = Acta pharmaceutica Sinica.
[79] Y. Feng,et al. [Protective effect of dl-3-n-butylphthalide on ischemic neurological damage and abnormal behavior in rats subjected to focal ischemia]. , 1995, Yao xue xue bao = Acta pharmaceutica Sinica.
[80] I. Reynolds,et al. Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation , 1995, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[81] P. Henrich-Noack,et al. Neuroprotective effects of Ginkgo biloba constituents , 1995 .
[82] Eugene M. Johnson,et al. Superoxide dismutase delays neuronal apoptosis: A role for reactive oxygen species in programmed neuronal death , 1995, Neuron.
[83] G. Jin,et al. Effects of (-)-stepholidine on firing activity of dopamine neurons in ventral tegmental area of rats. , 1992, Zhongguo yao li xue bao = Acta pharmacologica Sinica.
[84] Huang Kai-xing,et al. THE ANTAGONISTIC EFFECTS OF TETRAHYDRO-PROTOBERBERINES ON DOPAMINE RECEPTORS: ELECTROPHYSIOLOGICAL STUDIES , 1992 .
[85] Bao-cun Sun,et al. Dual actions of (−)-stepholidine on dopamine receptor subtypes after substantia nigra lesion , 1992, Neurochemistry International.
[86] J. Zheng. [Screening of active anti-inflammatory, immunosuppressive and antifertility components of Tripterygium wilfordii. III. A comparison of the antiinflammatory and immunosuppressive activities of 7 diterpene lactone epoxide compounds in vivo]. , 1991, Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae.
[87] I. Adachi,et al. Inhibitory effect of triptolide on colony formation of breast and stomach cancer cell lines. , 1991, Zhongguo yao li xue bao = Acta pharmacologica Sinica.
[88] J. T. Zhang,et al. [Anti-lipidperoxidation and cerebral protective effects of clausenamide]. , 1991, Yao xue xue bao = Acta pharmaceutica Sinica.
[89] L. Pu,et al. [Effects of triptolide on T lymphocyte functions in mice]. , 1990, Zhongguo yao li xue bao = Acta pharmacologica Sinica.
[90] J. Krieglstein,et al. Effects of Ginkgo biloba constituents related to protection against brain damage caused by hypoxia. , 1988, Pharmacological research communications.