Monitoring physiological signals using nonintrusive sensors installed in daily life equipment

PurposeWith increasing concern for well-being and recent advances in biomedical technology, healthcare is extending beyond the realm of hospitals. Nonintrusive home healthcare monitoring is essential for ensuring long-term use and preservation of an uninterrupted daily life. Herein, we describe recent progress in nonintrusive measurements of ECG, PPG, respiration and blood pressure using sensors installed in everyday household equipment.MethodsBallistocardiograms (BCG) were measured nonintrusively using air mattresses in a loadcell-based system. Electrocardiograms (ECG) were measured using capacitively coupled electrodes without direct contact to exposed bare skin, and these electrodes were installed in chairs, beds, belts and toilet seats. Photoplethysmograms (PPG) were measured over clothes by optimally controlling the input intensity of light and the associated electrodes were installed on chairs. To estimate blood pressure, pulse arrival time (PAT) was calculated from nonintrusively measured ECG and PPG. Blood pressure was estimated using a linear estimating equation with parameters fitted for each subject.ResultsHeart rate, heart rate variability, and respiration were all derived accurately with high correlation, and blood pressure was estimated from these nonintrusively measured signals.ConclusionsBy applying nonintrusive methods for measuring biological signals, we can monitor our health status without interrupting ordinary daily activities. This concept can be applied for ubiquitous healthcare, thus extending healthcare beyond hospitals.

[1]  Adrian D. C. Chan,et al.  Wavelet Distance Measure for Person Identification Using Electrocardiograms , 2008, IEEE Transactions on Instrumentation and Measurement.

[2]  C W Whitney,et al.  Sleep-disordered breathing and cardiovascular disease: cross-sectional results of the Sleep Heart Health Study. , 2001, American journal of respiratory and critical care medicine.

[3]  J.L. Jacobs,et al.  Characterization of a novel heart and respiratory rate sensor , 2004, The 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[4]  H. Otzenberger,et al.  Temporal relationship between dynamic heart rate variability and electroencephalographic activity during sleep in man , 1997, Neuroscience Letters.

[5]  G. V. Marie,et al.  The relationship between arterial blood pressure and pulse transit time during dynamic and static exercise. , 1984, Psychophysiology.

[6]  P. Obrist,et al.  Pulse transit time: relationship to blood pressure and myocardial performance. , 1979, Psychophysiology.

[7]  R González-Landaeta,et al.  Heart rate detection from an electronic weighing scale. , 2008, Physiological measurement.

[8]  Choi Jin-Wook,et al.  A New Method for Unconstrained Pulse Arrival Time (PAT) Measurement on a Chair , 2006 .

[9]  P Lavie,et al.  Obstructive Sleep Apnea and Hypertension: From Correlative to Causative Relationship , 2001, Journal of clinical hypertension.

[10]  Park Eun-Kyoung,et al.  A Study on the Estimation of Continuous Blood Pressure using PIT and Biometric Parameters , 2006 .

[11]  T. D. Clark,et al.  Electric potential probes - new directions in the remote sensing of the human body , 2002 .

[12]  J. Alihanka,et al.  A static charge sensitive bed. A new method for recording body movements during sleep. , 1979, Electroencephalography and clinical neurophysiology.

[13]  D. Hillman,et al.  Association of sleep apnoea with myocardial infarction in men , 1990, The Lancet.

[14]  C. Taylor,et al.  The covariation of blood pressure and pulse transit time in hypertensive patients. , 1981, Psychophysiology.

[15]  Kwangsuk Park,et al.  Air mattress sensor system with balancing tube for unconstrained measurement of respiration and heart beat movements , 2005, Physiological measurement.

[16]  Lei Wang,et al.  Multichannel Reflective PPG Earpiece Sensor With Passive Motion Cancellation , 2007, IEEE Transactions on Biomedical Circuits and Systems.

[17]  Richard O. Claus,et al.  A 'smart' bed for non-intrusive monitoring of patient physiological factors , 2004 .

[18]  A Steptoe,et al.  Pulse wave velocity and blood pressure change: calibration and applications. , 1976, Psychophysiology.

[19]  M. Ishijima Monitoring of electrocardiograms in bed without utilizing body surface electrodes , 1993, IEEE Transactions on Biomedical Engineering.

[20]  Youngjoon Chee,et al.  Development of a nonintrusive blood pressure estimation system for computer users. , 2007, Telemedicine journal and e-health : the official journal of the American Telemedicine Association.

[21]  Ikuo Imazeki,et al.  Immunomodulating effect of vitamin D3 derivatives on type-1 cellular immunity. , 2006, Biomedical research.

[22]  S. Tanaka,et al.  Unconstrained and non-invasive measurement of heart-beat and respiration periods using a phonocardiographic sensor , 2002, Medical and Biological Engineering and Computing.

[23]  B. Larive,et al.  Evaluation of the Harmonized Alert Sensing Technology Device for Hemodynamic Monitoring in Chronic Hemodialysis Patients , 2003, ASAIO journal.

[24]  P. Öberg,et al.  Monitoring of respiratory and heart rates using a fibre-optic sensor , 1992, Medical and Biological Engineering and Computing.

[25]  Kwang Suk Park,et al.  Non-constraining sleep/wake monitoring system using bed actigraphy , 2006, Medical & Biological Engineering & Computing.

[26]  J. Abisheganaden,et al.  Respiratory monitoring using an air-mattress system , 2000, Physiological measurement.

[27]  G Calcagnini,et al.  Effects of sleep stage and age on short-term heart rate variability during sleep in healthy infants and children. , 2000, Chest.

[28]  Yong Gyu Lim,et al.  ECG measurement on a chair without conductive contact , 2006, IEEE Transactions on Biomedical Engineering.

[29]  Alpo Värri,et al.  Automatic detection of spiking events in EMFi sheet during sleep. , 2006, Medical engineering & physics.

[30]  K. Wesseling,et al.  Fifteen years experience with finger arterial pressure monitoring: assessment of the technology. , 1998, Cardiovascular research.

[31]  Hiroshi Sameshima,et al.  Continuous Systolic Blood Pressure Monitoring By the Difference in Electrocardiogram and Pulse Oximetry in Near-Term, Exteriorized Goat Fetuses , 2003, Journal of the Society for Gynecologic Investigation.

[32]  Ko Keun Kim,et al.  Nonintrusive biological signal monitoring in a car to evaluate a driver's stress and health state. , 2009, Telemedicine journal and e-health : the official journal of the American Telemedicine Association.

[33]  Kajiro Watanabe,et al.  Noncontact method for sleep stage estimation , 2004, IEEE Transactions on Biomedical Engineering.

[34]  T. Ozawa,et al.  Accuracy of a continuous blood pressure monitor based on arterial tonometry. , 1993, Hypertension.

[35]  H. Harry Asada,et al.  Artifact-resistant power-efficient design of finger-ring plethysmographic sensors , 2001, IEEE Transactions on Biomedical Engineering.

[36]  Yuan-Ting Zhang,et al.  Physiological Signal Based Entity Authentication for Body Area Sensor Networks and Mobile Healthcare Systems , 2005, 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference.

[37]  Xin Zhu,et al.  Unconstrained monitoring of long-term heart and breath rates during sleep , 2008, Physiological measurement.

[38]  A. Rechtschaffen,et al.  A manual of standardized terminology, technique and scoring system for sleep stages of human subjects , 1968 .

[39]  Hyun Seok Choi,et al.  Unconstrained respiration and heart rate monitoring system based on a PPG pillow during sleep , 2008, EMBC 2008.

[40]  Ko Keun Kim,et al.  Effect of confounding factors on blood pressure estimation using pulse arrival time , 2008, Physiological measurement.

[41]  S. Tanaka,et al.  Fully Automatic System for Monitoring Blood Pressure from a Toilet-Seat Using the Volume-Oscillometric Method , 2005, 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference.

[42]  Kenzo Hirao,et al.  Correlation between electroencephalography and heart rate variability during sleep , 2003, Psychiatry and clinical neurosciences.

[43]  L A Geddes,et al.  Pulse transit time as an indicator of arterial blood pressure. , 1981, Psychophysiology.

[44]  Xiaorong Gao,et al.  THE RELATIONSHIP OF HRV TO SLEEP EEG AND SLEEP RHYTHM , 2005, The International journal of neuroscience.

[45]  Ko Keun Kim,et al.  Photoplethysmogram Measurement Without Direct Skin-to-Sensor Contact Using an Adaptive Light Source Intensity Control , 2009, IEEE Transactions on Information Technology in Biomedicine.

[46]  Yong Gyu Lim,et al.  ECG Recording on a Bed During Sleep Without Direct Skin-Contact , 2007, IEEE Transactions on Biomedical Engineering.

[47]  Kwang Suk Park,et al.  A new approach for non-intrusive monitoring of blood pressure on a toilet seat. , 2006, Physiological measurement.