Analytical model for SPECT detector concepts

Pixellated cadmium-zinc telluride (CZT) detectors, providing higher spatial resolution and energy resolution than current gamma cameras, will improve the image quality of SPECT detector systems. Their performance has to be evaluated in terms of resolution, detector efficiency and image quality in a similar way as has been done earlier for NaI detectors. We have developed an analytical model for spatial resolution and geometric efficiency of collimators specifically for pixellated CZT based detectors. We derive an exact description for a variety of static and rotating detector concepts, use standard performance criteria for detection efficiency, and adapt measures for spatial resolution of pixellated detectors, based on the sampling of the single pixel response function (SPRF). The concept is extended to enable a comparative description of continuous scintillator based SPECT cameras. Tradeoffs among resolution, efficiency, signal-to-noise ratio (SNR) and minimum detectable contrast have been investigated for different detector concepts. Our analysis shows that concepts using rotating collimators suffer from noise accumulation, except for purely hot spot imaging. A finite optimization of current SPECT systems can be done based on this analytical model, and a further increase in image quality will be achieved by the higher spatial resolution and energy resolution of solid-state detectors.

[1]  S. Webb,et al.  The experimental evaluation of a prototype rotating slat collimator for planar gamma camera imaging. , 1995, Physics in medicine and biology.

[2]  S. Webb,et al.  Monte Carlo modelling of the performance of a rotating slit-collimator for improved planar gamma-camera imaging. , 1992, Physics in medicine and biology.

[3]  N. Sato,et al.  Assessment of left ventricular function using solid-state gamma camera equipped with a highly-sensitive collimator , 2003, Annals of nuclear medicine.

[4]  K. Koral,et al.  SPRINT II: a second generation single photon ring tomograph. , 1988, IEEE transactions on medical imaging.

[5]  S. J. Friesenhahn,et al.  CdZnTe solid-state gamma camera , 1997 .

[6]  Robert Stanton,et al.  Radiological Imaging: The Theory of Image Formation, Detection, and Processing , 1983 .

[7]  H. Anger,et al.  MAPPING THE DISTRIBUTION OF GAMMA-RAY-EMITTING ISOTOPES WITH THE SCINTILLATION CAMERA , 1958 .

[8]  J. F. Butler,et al.  CdTe low level gamma detectors based on a new crystal growth method , 1988 .

[9]  D. Gagnon,et al.  CdZnTe strip detector SPECT imaging with a slit collimator. , 2004, Physics in medicine and biology.

[10]  G Muehllehner,et al.  Section imaging by computer calculation. , 1971, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[11]  P H Murphy,et al.  Radionuclide emission computed tomography of the head with 99mCc and a scintillation camera. , 1977, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[12]  Steve Webb,et al.  A prototype rotating slat collimator for single photon emission computed tomography , 1996, IEEE Trans. Medical Imaging.

[13]  H. Anger SCINTILLATION CAMERA WITH MULTICHANNEL COLLIMATORS. , 1964, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[14]  R. G. Simpson,et al.  Imaging with rotating slit apertures and rotating collimators. , 1982, Medical physics.

[15]  C. Scheiber,et al.  NEW DEVELOPMENTS IN CLINICAL APPLICATIONS OF CDTE AND CDZNTE DETECTORS , 1996 .

[16]  G T Gullberg,et al.  Review of convergent beam tomography in single photon emission computed tomography. , 1992, Physics in medicine and biology.

[17]  Scott D. Metzler,et al.  Analytic determination of the resolution-equivalent effective diameter of a pinhole collimator , 2004, IEEE Transactions on Medical Imaging.

[18]  R. Q. Edwards,et al.  Image Separation Radioisotope Scanning , 1963 .