Biocompatibility and intradiscal application of a thermoreversible celecoxib-loaded poly-N-isopropylacrylamide MgFe-layered double hydroxide hydrogel in a canine model

[1]  O. M. Torre,et al.  Fibrin-genipin annulus fibrosus sealant as a delivery system for anti-TNFα drug. , 2015, The spine journal : official journal of the North American Spine Society.

[2]  Nicole Willems,et al.  A novel injectable thermoresponsive and cytocompatible gel of poly(N-isopropylacrylamide) with layered double hydroxides facilitates siRNA delivery into chondrocytes in 3D culture. , 2015, Acta biomaterialia.

[3]  Benjamin A Walter,et al.  Inflammatory Kinetics and Efficacy of Anti-inflammatory Treatments on Human Nucleus Pulposus Cells , 2015, Spine.

[4]  James D. Kang,et al.  Molecular Basis of Intervertebral Disc Degeneration and Herniations: What Are the Important Translational Questions? , 2015, Clinical orthopaedics and related research.

[5]  Gustav J Strijkers,et al.  Intradiscal application of rhBMP-7 does not induce regeneration in a canine model of spontaneous intervertebral disc degeneration , 2015, Arthritis Research & Therapy.

[6]  Russell V. Lenth,et al.  Java Applets for Power and Sample Size , 2015 .

[7]  Sytze J Buwalda,et al.  Release behavior and intra-articular biocompatibility of celecoxib-loaded acetyl-capped PCLA-PEG-PCLA thermogels. , 2014, Biomaterials.

[8]  Keita Ito,et al.  The Effect of a Cyclooxygenase 2 Inhibitor on Early Degenerated Human Nucleus Pulposus Explants , 2013, Global spine journal.

[9]  V. Rives,et al.  Layered double hydroxides as drug carriers and for controlled release of non-steroidal antiinflammatory drugs (NSAIDs): a review. , 2013, Journal of controlled release : official journal of the Controlled Release Society.

[10]  H. Hazewinkel,et al.  Intervertebral disc disease in dogs - part 1: a new histological grading scheme for classification of intervertebral disc degeneration in dogs. , 2013, Veterinary journal.

[11]  G. Voorhout,et al.  Design, synthesis, imaging, and biomechanics of a softness-gradient hydrogel nucleus pulposus prosthesis in a canine lumbar spine model. , 2012, Journal of biomedical materials research. Part B, Applied biomaterials.

[12]  M. Alini,et al.  Injectable thermoreversible hyaluronan-based hydrogels for nucleus pulposus cell encapsulation , 2012, European Spine Journal.

[13]  Kyle Mairose.  Treatment of Chronic Low Back Pain , 2012 .

[14]  Anne-Sofie Lagerstedt,et al.  The Dog as an Animal Model for Intervertebral Disc Degeneration? , 2012, Spine.

[15]  H. Hazewinkel,et al.  Reliability of macroscopic grading of intervertebral disk degeneration in dogs by use of the Thompson system and comparison with low-field magnetic resonance imaging findings. , 2011, American journal of veterinary research.

[16]  G. Voorhout,et al.  Evaluation of intervertebral disk degeneration in chondrodystrophic and nonchondrodystrophic dogs by use of Pfirrmann grading of images obtained with low-field magnetic resonance imaging. , 2011, American journal of veterinary research.

[17]  James D. Kang,et al.  Prostaglandin E2 and prostaglandin F2α differentially modulate matrix metabolism of human nucleus pulposus cells , 2010, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[18]  A. Hofman,et al.  The Association Between Lumbar Disc Degeneration and Low Back Pain: The Influence of Age, Gender, and Individual Radiographic Features , 2010, Spine.

[19]  Patricia Dolan,et al.  The internal mechanical functioning of intervertebral discs and articular cartilage, and its relevance to matrix biology. , 2009, Matrix biology : journal of the International Society for Matrix Biology.

[20]  D. Das,et al.  Solute Transport in Intervertebral Disc , 2009, Annals of the New York Academy of Sciences.

[21]  James M. Anderson,et al.  Foreign body reaction to biomaterials. , 2008, Seminars in immunology.

[22]  Dawn M Elliott,et al.  The Effect of Relative Needle Diameter in Puncture and Sham Injection Animal Models of Degeneration , 2008, Spine.

[23]  J. Kristl,et al.  Influence of polymers on the bioavailability of microencapsulated celecoxib , 2007, Journal of microencapsulation.

[24]  S. Grösch,et al.  Cyclooxygenase-2 (COX-2)-independent anticarcinogenic effects of selective COX-2 inhibitors. , 2006, Journal of the National Cancer Institute.

[25]  S. Abramson,et al.  Prostaglandin E2 synthesis and secretion: the role of PGE2 synthases. , 2006, Clinical immunology.

[26]  Masahiro Kurosaka,et al.  Effects of Cyclic Mechanical Stress on the Production of Inflammatory Agents by Nucleus Pulposus and Anulus Fibrosus Derived Cells In Vitro , 2006, Spine.

[27]  J. Bijlsma,et al.  Differential direct effects of cyclo-oxygenase-1/2 inhibition on proteoglycan turnover of human osteoarthritic cartilage: an in vitro study , 2005, Arthritis Research & Therapy.

[28]  P. Roughley,et al.  Tumor Necrosis Factor&agr; Modulates Matrix Production and Catabolism in Nucleus Pulposus Tissue , 2005, Spine.

[29]  P. Manley,et al.  Collagenolytic protease expression in cranial cruciate ligament and stifle synovial fluid in dogs with cranial cruciate ligament rupture. , 2005, Veterinary surgery : VS.

[30]  A. Freemont,et al.  The role of interleukin-1 in the pathogenesis of human Intervertebral disc degeneration , 2005, Arthritis research & therapy.

[31]  P. Roughley.  Biology of Intervertebral Disc Aging and Degeneration: Involvement of the Extracellular Matrix , 2004, Spine.

[32]  Owen J. Marshall.  PerlPrimer: cross-platform, graphical primer design for standard, bisulphite and real-time PCR , 2004, Bioinform..

[33]  S. Goldring,et al.  The role of cytokines in cartilage matrix degeneration in osteoarthritis. , 2004, Clinical orthopaedics and related research.

[34]  R. Ettlinger,et al.  Etoricoxib reduced pain and disability and improved quality of life in patients with chronic low back pain: a 3 month, randomized, controlled trial , 2004, Scandinavian journal of rheumatology.

[35]  W. Gianni,et al.  Preclinical evaluation of the nonsteroidal anti‐inflammatory agent celecoxib on malignant mesothelioma chemoprevention , 2004, International journal of cancer.

[36]  A. Mangione,et al.  Treatment of chronic low back pain with etoricoxib, a new cyclo-oxygenase-2 selective inhibitor: improvement in pain and disability--a randomized, placebo-controlled, 3-month trial. , 2003, The journal of pain : official journal of the American Pain Society.

[37]  Michael Zuker,et al.  Mfold web server for nucleic acid folding and hybridization prediction , 2003, Nucleic Acids Res..

[38]  S. Jang,et al.  mRNA Expression of Cytokines and Chemokines in Herniated Lumbar Intervertebral Discs , 2002, Spine.

[39]  Allan S Hoffman,et al.  Hydrogels for biomedical applications. , 2002, Advanced drug delivery reviews.

[40]  D A Jones,et al.  The pathophysiology of the intervertebral disc. , 2001, Joint, bone, spine : revue du rhumatisme.

[41]  M. Vaughn,et al.  Pharmacokinetics of celecoxib after oral administration in dogs and humans: effect of food and site of absorption. , 2001, The Journal of pharmacology and experimental therapeutics.

[42]  M. Peters-Golden,et al.  Arachidonic Acid Is Preferentially Metabolized by Cyclooxygenase-2 to Prostacyclin and Prostaglandin E2 * , 1999, The Journal of Biological Chemistry.

[43]  V C Mow,et al.  The viscoelastic behavior of the non-degenerate human lumbar nucleus pulposus in shear. , 1997, Journal of biomechanics.

[44]  Van C. Mow,et al.  Is the Nucleus Pulposus a Solid or a Fluid? Mechanical Behaviors of the Nucleus Pulposus of the Human Intervertebral Disc , 1996, Spine.

[45]  James D. Kang,et al.  Herniated Lumbar Intervertebral Discs Spontaneously Produce Matrix Metalloproteinases, Nitric Oxide, Interleukin-6, and Prostaglandin E2 , 1996, Spine.

[46]  James D. Kang,et al.  Herniated Cervical Intervertebral Discs Spontaneously Produce Matrix Metalloproteinases, Nitric Oxide, Interleukin‐6, and Prostaglandin E2 , 1995, Spine.

[47]  I. Shapiro,et al.  Role of cytokines in intervertebral disc degeneration: pain and disc content , 2014, Nature Reviews Rheumatology.

[48]  R Core Team,et al.  R: A language and environment for statistical computing. , 2014 .

[49]  J. West,et al.  Thermo-responsive systems for controlled drug delivery. , 2008, Expert opinion on drug delivery.

[50]  J. Ralphs,et al.  Are animal models useful for studying human disc disorders/degeneration? , 2007, European Spine Journal.

[51]  R W Farndale,et al.  A direct spectrophotometric microassay for sulfated glycosaminoglycans in cartilage cultures. , 1982, Connective tissue research.

[52]  C HIRSCH,et al.  Studies on structural changes in the lumbar annulus fibrosus. , 1952, Acta orthopaedica Scandinavica.

[53]  H. Kristensen.  An improved method of decalcification. , 1948, Stain technology.