Susceptibility to type I diabetes: HLA-DQ and DR revisited.

[1]  W. Klitz,et al.  Association of HLA-DPB1*0301 With IDDM in Mexican-Americans , 1996, Diabetes.

[2]  J. She,et al.  HLA-encoded susceptibility to insulin-dependent diabetes mellitus is determined by DR and DQ genes as well as their linkage disequilibria in a Chinese population. , 1995, Human immunology.

[3]  G. Thomson,et al.  Affected-sib-pair mapping of a novel susceptibility gene to insulin-dependent diabetes mellitus (IDDM8) on chromosome 6q25-q27. , 1995, American journal of human genetics.

[4]  G. Nepom,et al.  HLA-DQ polymorphisms are highly selective for peptide binding interactions. , 1995, Journal of immunology.

[5]  M. Christie,et al.  Relationship of the 37,000- and 40,000-M(r) tryptic fragments of islet antigens in insulin-dependent diabetes to the protein tyrosine phosphatase-like molecule IA-2 (ICA512). , 1995, The Journal of clinical investigation.

[6]  F. Cucca,et al.  The distribution of DR4 haplotypes in Sardinia suggests a primary association of type I diabetes with DRB1 and DQB1 loci. , 1995, Human immunology.

[7]  H. Heimberg,et al.  DRB1*0403 Protects Against IDDM in Caucasians With the High-Risk Heterozygous DQA1*0301-DQB1*0302/DQA1*0501-DQB1*0201 Genotype , 1995, Diabetes.

[8]  J. Strominger,et al.  Selective binding of self peptides to disease-associated major histocompatibility complex (MHC) molecules: a mechanism for MHC-linked susceptibility to human autoimmune diseases , 1995, The Journal of experimental medicine.

[9]  N. Maclaren,et al.  Association of LMP2 and LMP7 genes within the major histocompatibility complex with insulin-dependent diabetes mellitus: population and family studies. , 1995, American journal of human genetics.

[10]  T. Lybrand,et al.  Polymorphic Amino Acid Variations in HLA-DQ Are Associated With Systematic Physical Property Changes and Occurrence of IDDM , 1995, Diabetes.

[11]  N. Maclaren,et al.  High risk HLA-DR/DQ genotypes for IDD confer susceptibility to autoantibodies but DQB1*0602 does not prevent them. , 1994, Journal of autoimmunity.

[12]  L. Field,et al.  A locus on chromosome 15q26 (IDDM3) produces susceptibility to insulin-dependent diabetes mellitus , 1994, Nature Genetics.

[13]  M. James,et al.  Genetic mapping of a susceptibility locus for insulin-dependent diabetes mellitus on chromosome llq , 1994, Nature.

[14]  J. Todd,et al.  A genome-wide search for human type 1 diabetes susceptibility genes , 1994, Nature.

[15]  G. Eisenbarth Mouse or Man: Is GAD the cause of type I diabetes? , 1994, Diabetes Care.

[16]  C. Janeway,et al.  Self peptides isolated from MHC glycoproteins of non-obese diabetic mice. , 1994, Journal of immunology.

[17]  E. Wakeland,et al.  Additive susceptibility to insulin-dependent diabetes conferred by HLA-DQB1 and insulin genes. , 1994, Autoimmunity.

[18]  M. de Carli,et al.  Human Th1 and Th2 cells: functional properties, regulation of development and role in autoimmunity. , 1994, Autoimmunity.

[19]  U. Gyllensten,et al.  Association of insulin-dependent diabetes mellitus in Taiwan with HLA class II DQB1 and DRB1 alleles. , 1993, Human immunology.

[20]  Å. Lernmark,et al.  HLA-DQ primarily confers protection and HLA-DR susceptibility in type I (insulin-dependent) diabetes studied in population-based affected families and controls. , 1993, American journal of human genetics.

[21]  F. Muntoni,et al.  Combinations of specific DRB1, DQA1, DQB1 haplotypes are associated with insulin-dependent diabetes mellitus in Sardinia. , 1993, Human immunology.

[22]  M. Spyropoulou,et al.  HLA CLASS II POLYMORPHISM AND IDDM SUSCEPTIBILITY IN THE GREEK POPULATION , 1993, European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics.

[23]  L. Harrison,et al.  Inverse relation between humoral and cellular immunity to glutamic acid decarboxylase in subjects at risk of insulin-dependent diabetes , 1993, The Lancet.

[24]  Henry A. Erlich,et al.  HLA class II alleles and susceptibility and resistance to insulin dependent diabetes mellitus in Mexican-American families , 1993, Nature Genetics.

[25]  G. Nepom,et al.  HLA-DQ allelic polymorphisms constrain patterns of class II heterodimer formation. , 1993, Journal of immunology.

[26]  P. Raskin,et al.  Genes for insulin-dependent diabetes mellitus (IDDM) in the major histocompatibility complex (MHC) of African-Americans. , 1993, Tissue antigens.

[27]  E. Thorsby,et al.  Role of HLA genes in predisposition to develop insulin-dependent diabetes mellitus. , 1992, Annals of medicine.

[28]  C. Boitard,et al.  Age-dependent HLA genetic heterogeneity of type 1 insulin-dependent diabetes mellitus. , 1992, The Journal of clinical investigation.

[29]  G. Hitman,et al.  Distribution of HLA-DQA1, -DQB1 and DRB1 alleles in black IDDM patients and controls from Zimbabwe. , 1992, Tissue antigens.

[30]  D. Cavan,et al.  Susceptibility to IDDM in a Chinese Population: Role of HLA Class II Alleles , 1992, Diabetes.

[31]  V. Lepage,et al.  Dose Effect of Cis- and Trans-Encoded HLA-DQαβ Heterodimers in IDDM Susceptibility , 1992, Diabetes.

[32]  M. Sheehy HLA and Insulin-Dependent Diabetes. A protective perspective , 1992, Diabetes.

[33]  M. Erlander,et al.  Autoimmunity to two forms of glutamate decarboxylase in insulin-dependent diabetes mellitus. , 1992, The Journal of clinical investigation.

[34]  A. Barnett,et al.  HLA-DQA1 and -DQB1 Alleles Associated With Genetic Susceptibility to IDDM in a Black Population , 1991, Diabetes.

[35]  H. Erlich,et al.  Implication of Specific DQB1 Alleles in Genetic Susceptibility and Resistance by Identification of IDDM Siblings With Novel HLA-DQB1 Allele and Unusual DR2 and DR1 Haplotypes , 1991, Diabetes.

[36]  E. Thorsby,et al.  Distribution of HLA-DRB1, -DQA1 and -DQB1 alleles and DQA1-DQB1 genotypes among Norwegian patients with insulin-dependent diabetes mellitus. , 1991, Tissue antigens.

[37]  A. Arnaiz-Villena,et al.  High frequency of the HLA-DRB1*0405-(Dw15)-DQw8 haplotype in Spaniards and its relationship to diabetes susceptibility. , 1991, Human immunology.

[38]  H. Erlich,et al.  MHC class-II molecules and autoimmunity. , 1991, Annual review of immunology.

[39]  G. Nepom A Unified Hypothesis for the Complex Genetics of HLA Associations With IDDM , 1990, Diabetes.

[40]  M. Atkinson,et al.  64 000 Mr autoantibodies as predictors of insulin-dependent diabetes , 1990, The Lancet.

[41]  F. Galibert,et al.  A combination of HLA-DQ beta Asp57-negative and HLA DQ alpha Arg52 confers susceptibility to insulin-dependent diabetes mellitus. , 1990, The Journal of clinical investigation.

[42]  H. Erlich,et al.  HLA-DQβ Sequence Polymorphism and Genetic Susceptibility to IDDM , 1990, Diabetes.

[43]  K. Gabbay,et al.  Primary Association of HLA-DQw8 With Type I Diabetes in DR4 Patients , 1989, Diabetes.

[44]  J. Todd,et al.  Identification of susceptibility loci for insulin-dependent diabetes mellitus by trans-racial gene mapping , 1989, Nature.

[45]  J. R. Rowe,et al.  A diabetes-susceptible HLA haplotype is best defined by a combination of HLA-DR and -DQ alleles. , 1989, The Journal of clinical investigation.

[46]  M. Baur,et al.  Genetic heterogeneity, modes of inheritance, and risk estimates for a joint study of Caucasians with insulin-dependent diabetes mellitus. , 1988, American journal of human genetics.

[47]  L. Harrison,et al.  Association of HLA-DQw3 (TA10−) With Type I Diabetes Occurs With DR3/4 but not DR1/4 Patients , 1988, Diabetes.

[48]  J. D. Lin,et al.  A strong association of HLA-DR 3/4 heterozygotes with insulin-dependent diabetes among Chinese in Taiwan. , 1988, Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association.

[49]  J. Todd,et al.  HLA-DQβ gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus , 1987, Nature.

[50]  S. Holbeck,et al.  Specific genomic markers for the HLA-DQ subregion discriminate between DR4+ insulin-dependent diabetes mellitus and DR4+ seropositive juvenile rheumatoid arthritis , 1986, The Journal of experimental medicine.

[51]  A. Cudworth,et al.  HL-A System and Diabetes Mellitus , 1975, Diabetes.

[52]  M. Blajchman,et al.  Histocompatibility (HL-A) Antigens, Lymphocytotoxic Antibodies and Tissue Antibodies in Patients with Diabetes Mellitus , 1973, Diabetes.