Two cases of lumbosacral myeloradiculitis with anti-aquaporin-4 antibody

Neuromyelitis optica (NMO) is an inflammatory disease of the CNS which is typically characterized by severe optic neuritis and transverse myelitis. Since the discovery of anti-aquaporin-4 (AQP4) antibody,[1][1],[2][2] an NMO-specific autoantibody, other unique features of NMO have been clarified.