Mutations in the dihydropteroate synthase gene of Pneumocystis jiroveci isolates from Portuguese patients with Pneumocystis pneumonia.

[1]  C. Beard,et al.  A New Name for Pneumocystis from Humans and New Perspectives on the Host-Pathogen Relationship , 2002, Emerging infectious diseases.

[2]  M. Zolfo,et al.  Mutations in dihydropteroate synthase gene of Pneumocystis carinii in HIV patients with Pneumocystis carinii pneumonia. , 2001, International journal of antimicrobial agents.

[3]  F. Antunes,et al.  Multilocus PCR-RFLP analysis of Cryptosporidium isolates from HIV-infected patients from Portugal. , 2001, Annals of tropical medicine and parasitology.

[4]  C. Beard,et al.  Effect of mutations in Pneumocystis carinii dihydropteroate synthase gene on outcome of P carinii pneumonia in patients with HIV-1: a prospective study , 2001, The Lancet.

[5]  Marina C Costa,et al.  PCR‐RFLP Analysis of the DHPS gene for the Study of Resistance of Pneumocystis carinii to Sulpha Drugs in Patients with Co‐infection PCP/HIV , 2001, The Journal of eukaryotic microbiology.

[6]  J. McLauchlin,et al.  Molecular Epidemiological Analysis of Cryptosporidiumspp. in the United Kingdom: Results of GenotypingCryptosporidium spp. in 1,705 Fecal Samples from Humans and 105 Fecal Samples from Livestock Animals , 2000, Journal of Clinical Microbiology.

[7]  C. Beard,et al.  Sulfa or sulfone prophylaxis and geographic region predict mutations in the Pneumocystis carinii dihydropteroate synthase gene. , 2000, The Journal of infectious diseases.

[8]  Yoshikazu Nakamura,et al.  Relationship between Mutations in Dihydropteroate Synthase of Pneumocystis carinii f. sp.hominis Isolates in Japan and Resistance to Sulfonamide Therapy , 2000, Journal of Clinical Microbiology.

[9]  S. Meshnick,et al.  Pneumocystis carinii mutations are associated with duration of sulfa or sulfone prophylaxis exposure in AIDS patients. , 2000, The Journal of infectious diseases.

[10]  C. Beard,et al.  Genetic variation in Pneumocystis carinii isolates from different geographic regions: implications for transmission. , 2000, Emerging infectious diseases.

[11]  J. Lundgren,et al.  Effects of mutations in Pneumocystis carinii dihydropteroate synthase gene on outcome of AIDS-associated P carinii pneumonia , 1999, The Lancet.

[12]  J. Guillot,et al.  Contribution of dihydropteroate synthase gene typing for Pneumocystis carinii f.sp. hominis epidemiology. , 1999, The Journal of eukaryotic microbiology.

[13]  J. Kovacs,et al.  Failure of co-trimoxazole in Pneumocystis carinii infection and mutations in dihydropteroate synthase gene , 1998, The Lancet.

[14]  S. Meshnick,et al.  Pneumocystis carinii mutations associated with sulfa and sulfone prophylaxis failures in AIDS patients , 1998, AIDS.

[15]  B. Nichols,et al.  Characterization of Mutations Contributing to Sulfathiazole Resistance in Escherichia coli , 1998, Antimicrobial Agents and Chemotherapy.

[16]  J. Champness,et al.  Crystal structure of the anti-bacterial sulfonamide drug target dihydropteroate synthase , 1997, Nature Structural Biology.

[17]  S. Meshnick,et al.  Dihydropteroate synthase polymorphisms in Pneumocystis carinii. , 1997, The Journal of infectious diseases.

[18]  M. Zolfo,et al.  Detection of Pneumocystis carinii DNA in blood by PCR is not of value for diagnosis of P. carinii pneumonia , 1996, Journal of clinical microbiology.

[19]  O. Sköld,et al.  Sulfonamide resistance in Neisseria meningitidis as defined by site-directed mutagenesis could have its origin in other species , 1995, Journal of bacteriology.

[20]  J. E. Hyde,et al.  Sequence variation of the hydroxymethyldihydropterin pyrophosphokinase: dihydropteroate synthase gene in lines of the human malaria parasite, Plasmodium falciparum, with differing resistance to sulfadoxine. , 1994, European journal of biochemistry.

[21]  C. Allegra,et al.  Activities of antifolate, antiviral, and other drugs in an immunosuppressed rat model of Pneumocystis carinii pneumonia , 1992, Antimicrobial Agents and Chemotherapy.

[22]  R. Miller,et al.  Amplification of mitochondrial ribosomal RNA sequences from Pneumocystis carinii DNA of rat and human origin. , 1990, Molecular and biochemical parasitology.

[23]  S. Lacks,et al.  Sulfonamide resistance in Streptococcus pneumoniae: DNA sequence of the gene encoding dihydropteroate synthase and characterization of the enzyme , 1987, Journal of bacteriology.

[24]  J. Helweg-Larsen,et al.  Rapid detection of dihydropteroate polymorphism in AIDS-related Pneumocystis carinii pneumonia by restriction fragment length polymorphism. , 2000, Scandinavian journal of infectious diseases.