Reinvestigating the clinical relevance of the m6A writer METTL3 in urothelial carcinoma of the bladder

[1]  A. Jemal,et al.  Cancer statistics, 2023 , 2023, CA: a cancer journal for clinicians.

[2]  C. Yi,et al.  Absolute quantification of single-base m^6A methylation in the mammalian transcriptome using GLORI , 2022, Nature Biotechnology.

[3]  S. Jaffrey,et al.  Alternative splicing of METTL3 explains apparently METTL3-independent m6A modifications in mRNA , 2022, PLoS biology.

[4]  S. Jaffrey,et al.  Hidden codes in mRNA: Control of gene expression by m6A. , 2022, Molecular cell.

[5]  Yang Li,et al.  JNK Signaling Promotes Bladder Cancer Immune Escape by Regulating METTL3-Mediated m6A Modification of PD-L1 mRNA. , 2022, Cancer research.

[6]  D. Barros-Silva,et al.  Downregulation of m6A writer complex member METTL14 in bladder urothelial carcinoma suppresses tumor aggressiveness , 2022, Molecular oncology.

[7]  Qiang Liu.  Current Advances in N6-Methyladenosine Methylation Modification During Bladder Cancer , 2022, Frontiers in Genetics.

[8]  Joshua M. Dempster,et al.  Chronos: a cell population dynamics model of CRISPR experiments that improves inference of gene fitness effects , 2021, Genome Biology.

[9]  Andrew J. Bannister,et al.  Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia , 2021, Nature.

[10]  Bin Zheng,et al.  A new m6A methylation-related gene signature for prognostic value in patient with urothelial carcinoma of the bladder , 2021, Bioscience reports.

[11]  Cuiping Yang,et al.  The role of m6A modification in the biological functions and diseases , 2021, Signal Transduction and Targeted Therapy.

[12]  F. He,et al.  METTL3 restrains papillary thyroid cancer progression via m6A/c-Rel/IL-8 mediated neutrophils infiltration. , 2021, Molecular Therapy.

[13]  Liang Peng,et al.  Deficiency of Mettl3 in Bladder Cancer Stem Cells Inhibits Bladder Cancer Progression and Angiogenesis , 2020, Frontiers in Cell and Developmental Biology.

[14]  Xiangyi Zheng,et al.  METTL3/YTHDF2 m6A axis promotes tumorigenesis by degrading SETD7 and KLF4 mRNAs in bladder cancer , 2020, Journal of cellular and molecular medicine.

[15]  Hui Cao,et al.  m6A RNA methylation regulators can contribute to malignant progression and impact the prognosis of bladder cancer , 2019, Bioscience reports.

[16]  Gang Yin,et al.  Functions of N6-methyladenosine and its role in cancer , 2019, Molecular Cancer.

[17]  S. Jaffrey,et al.  Reading, writing and erasing mRNA methylation , 2019, Nature Reviews Molecular Cell Biology.

[18]  W. Min,et al.  N6-methyladenosine modification of ITGA6 mRNA promotes the development and progression of bladder cancer , 2019, EBioMedicine.

[19]  Matthew Stephens,et al.  Detailed modeling of positive selection improves detection of cancer driver genes , 2019, Nature Communications.

[20]  D. Lin,et al.  METTL3 facilitates tumor progression via an m6A-IGF2BP2-dependent mechanism in colorectal carcinoma , 2019, Molecular Cancer.

[21]  Hongcheng Lu,et al.  METTL3 promote tumor proliferation of bladder cancer by accelerating pri-miR221/222 maturation in m6A-dependent manner , 2019, Molecular Cancer.

[22]  Q. Lan,et al.  The Critical Role of RNA m6A Methylation in Cancer. , 2019, Cancer research.

[23]  W. Min,et al.  Dynamic m6A mRNA methylation reveals the role of METTL3-m6A-CDCP1 signaling axis in chemical carcinogenesis , 2019, Oncogene.

[24]  L. Chee,et al.  Pan-Cancer Analyses Reveal Genomic Features of FOXM1 Overexpression in Cancer , 2019, Cancers.

[25]  Yu Liang,et al.  The m6A methyltransferase METTL3 promotes bladder cancer progression via AFF4/NF-κB/MYC signaling network , 2019, Oncogene.

[26]  Chuan He,et al.  m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer , 2018, Nature Cell Biology.

[27]  Kwok-Kin Wong,et al.  mRNA circularization by METTL3-eIF3h enhances translation and promotes oncogenesis , 2018, Nature.

[28]  Chris Berdik.  Unlocking bladder cancer , 2017, Nature.

[29]  Deniz M. Ozata,et al.  CRISPR/Cas9-mediated genome editing induces exon skipping by alternative splicing or exon deletion , 2017, Genome Biology.

[30]  M. Helm,et al.  Analysis of RNA modifications by liquid chromatography-tandem mass spectrometry. , 2016, Methods.

[31]  Qiang Wang,et al.  Structural basis of N6-adenosine methylation by the METTL3–METTL14 complex , 2016, Nature.

[32]  Erez Y. Levanon,et al.  m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation , 2015, Science.

[33]  J. Reifenrath,et al.  Different approaches for interpretation and reporting of immunohistochemistry analysis results in the bone tissue – a review , 2014, Diagnostic Pathology.

[34]  Jukka Westermarck,et al.  ColonyArea: An ImageJ Plugin to Automatically Quantify Colony Formation in Clonogenic Assays , 2014, PloS one.

[35]  Kevin W Eliceiri,et al.  NIH Image to ImageJ: 25 years of image analysis , 2012, Nature Methods.

[36]  Xiangyi Zheng,et al.  METTL3/YTHDF2 m 6A Axis Promotes Tumorigenesis by Degrading SETD7 and KLF4 mRNAs in Bladder Cancer , 2019, SSRN Electronic Journal.

[37]  Howard Y. Chang,et al.  m6A RNA modification controls cell fate transition in mammalian embryonic stem cells , 2014 .