Crystal Structure of a Truncated Epidermal Growth Factor Receptor Extracellular Domain Bound to Transforming Growth Factor α
暂无分享,去创建一个
Edouard C. Nice | Colin W. Ward | Robert N. Jorissen | Hong-Jian Zhu | George O. Lovrecz | R. Jorissen | A. Burgess | F. Walker | E. Nice | Hong-Jian Zhu | N. Mckern | C. Ward | T. Garrett | T. Adams | Francesca Walker | Meizhen Lou | G. Lovrecz | Timothy E. Adams | Antony W. Burgess | Peter A. Hoyne | M. Lou | T. Elleman | P. Hoyne | Thomas P.J. Garrett | Neil M. McKern | Thomas C. Elleman | Morry J. Frenkel | M. J. Frenkel
[1] J. Chai,et al. Crystal Structure of Human Epidermal Growth Factor and Its Dimerization* , 2001, The Journal of Biological Chemistry.
[2] David F. Burke,et al. Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin , 2000, Nature.
[3] Charles Eigenbrot,et al. Crystal Structure at 1.7 Å Resolution of VEGF in Complex with Domain 2 of the Flt-1 Receptor , 1997, Cell.
[4] P. Seeburg,et al. Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells , 1984, Nature.
[5] I. Campbell,et al. The solution structure of human epidermal growth factor , 1987, Nature.
[6] M. Ultsch,et al. Human growth hormone and extracellular domain of its receptor: crystal structure of the complex. , 1992, Science.
[7] A. Ullrich,et al. Stabilization of an active dimeric form of the epidermal growth factor receptor by introduction of an inter-receptor disulfide bond. , 1994, The Journal of biological chemistry.
[8] W R Taylor,et al. On the tertiary structure of the extracellular domains of the epidermal growth factor and insulin receptors. , 1987, Biochimica et biophysica acta.
[9] C. Chothia,et al. The atomic structure of protein-protein recognition sites. , 1999, Journal of molecular biology.
[10] Role of the 6‐20 disulfide bridge in the structure and activity of epidermal growth factor , 1998, Protein science : a publication of the Protein Society.
[11] A. Ullrich,et al. Chicken epidermal growth factor (EGF) receptor: cDNA cloning, expression in mouse cells, and differential binding of EGF and transforming growth factor alpha , 1988, Molecular and cellular biology.
[12] R. Jorissen,et al. Identification of a determinant of epidermal growth factor receptor ligand-binding specificity using a truncated, high-affinity form of the ectodomain. , 2001, Biochemistry.
[13] Hyun-soo Cho,et al. Structure of the Extracellular Region of HER3 Reveals an Interdomain Tether , 2002, Science.
[14] D. Vizard,et al. Immunoaffinity purification of FLAG epitope-tagged bacterial alkaline phosphatase using a novel monoclonal antibody and peptide elution. , 1994, BioTechniques.
[15] K L King,et al. Biological response to ErbB ligands in nontransformed cell lines correlates with a specific pattern of receptor expression. , 1998, Endocrinology.
[16] J. Schlessinger,et al. Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization. , 2000, Molecular cell.
[17] H. Scheraga,et al. Solution structure of murine epidermal growth factor: determination of the polypeptide backbone chain-fold by nuclear magnetic resonance and distance geometry. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[18] H. Kawasaki,et al. A 40-kDa epidermal growth factor/transforming growth factor alpha-binding domain produced by limited proteolysis of the extracellular domain of the epidermal growth factor receptor. , 1993, The Journal of biological chemistry.
[19] C. Betzel,et al. Protein microheterogeneity and crystal habits: the case of epidermal growth factor receptor isoforms as isolated in a multicompartment electrolyzer with isoelectric membranes. , 1994, Journal of chromatography. A.
[20] D. Banner,et al. Crystal structure of the soluble human 55 kd TNF receptor-human TNFβ complex: Implications for TNF receptor activation , 1993, Cell.
[21] T. Kirsch,et al. Crystal structure of the BMP-2–BRIA ectodomain complex , 2000, Nature Structural Biology.
[22] Crystallization and preliminary X-ray crystallographic analysis of the EGF receptor ectodomain. , 1998, Acta crystallographica. Section D, Biological crystallography.
[23] I. Campbell,et al. A high-resolution 1H-NMR study of human transforming growth factor alpha. Structure and pH-dependent conformational interconversion. , 1989, European journal of biochemistry.
[24] N. Mckern,et al. Crystal structure of the first three domains of the type-1 insulin-like growth factor receptor , 1998, Nature.
[25] J. Schlessinger,et al. Regulation of signal transduction and signal diversity by receptor oligomerization. , 1994, Trends in biochemical sciences.
[26] C. A. Guyer,et al. Identification of Residues of the Epidermal Growth Factor Receptor Proximal to Residue 45 of Bound Epidermal Growth Factor* , 1996, The Journal of Biological Chemistry.
[27] A. Burgess,et al. Structure-Function relationships for the EGF/TGF-α family of mitogens , 1994 .
[28] H. Scheraga,et al. Solution structure of human type-alpha transforming growth factor determined by heteronuclear NMR spectroscopy and refined by energy minimization with restraints. , 1993, Biochemistry.
[29] I. Maruyama,et al. Activation of preformed EGF receptor dimers by ligand-induced rotation of the transmembrane domain. , 2001, Journal of molecular biology.
[30] S. Nakanishi,et al. Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor , 2000, Nature.
[31] Jae-Hoon Kim,et al. Crystal Structure of the Complex of Human Epidermal Growth Factor and Receptor Extracellular Domains , 2002, Cell.
[32] C. Ward,et al. Insulin and epidermal growth factor receptors contain the cysteine repeat motif found in the tumor necrosis factor receptor , 1995, Proteins.
[33] D. Kohda,et al. Three-dimensional nuclear magnetic resonance structures of mouse epidermal growth factor in acidic and physiological pH solutions. , 1994, Biochemistry.
[34] R J Read,et al. Crystallography & NMR system: A new software suite for macromolecular structure determination. , 1998, Acta crystallographica. Section D, Biological crystallography.
[35] Y. Yarden. The EGFR family and its ligands in human cancer. signalling mechanisms and therapeutic opportunities. , 2001, European journal of cancer.
[36] M. Sliwkowski,et al. High-resolution solution structure of the EGF-like domain of heregulin-alpha. , 1996, Biochemistry.
[37] D Eisenberg,et al. Identification of a Heregulin Binding Site in HER3 Extracellular Domain* , 2001, The Journal of Biological Chemistry.
[38] Y. Yarden,et al. Untangling the ErbB signalling network , 2001, Nature Reviews Molecular Cell Biology.
[39] I. Campbell,et al. The solution structure of human transforming growth factor alpha. , 1993, European journal of biochemistry.
[40] R. Woltjer,et al. Direct identification of residues of the epidermal growth factor receptor in close proximity to the amino terminus of bound epidermal growth factor. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[41] N. Kunishima,et al. Atomic structure of the GCSF–receptor complex showing a new cytokine–receptor recognition scheme , 1999, Nature.
[42] D. Kohda,et al. Solution structure of the epidermal growth factor‐like domain of heregulin‐alpha, a ligand for p180erbB‐4. , 1994, The EMBO journal.
[43] Colin W. Ward,et al. The relationship between the L1 and L2 domains of the insulin and epidermal growth factor receptors and leucine-rich repeat modules , 2001, BMC Bioinformatics.
[44] Joseph Schlessinger,et al. Crystal Structures of Two FGF-FGFR Complexes Reveal the Determinants of Ligand-Receptor Specificity , 2000, Cell.
[45] D. Engelman,et al. Two EGF molecules contribute additively to stabilization of the EGFR dimer , 1997, The EMBO journal.
[46] L. Wang,et al. Human epidermal growth factor (EGF) receptor sequence recognized by EGF competitive monoclonal antibodies. Evidence for the localization of the EGF-binding site. , 1989, The Journal of biological chemistry.
[47] D. Stern,et al. Specificity within the EGF family/ErbB receptor family signaling network , 1998, BioEssays : news and reviews in molecular, cellular and developmental biology.
[48] J. Biegel,et al. Frequent expression of a mutant epidermal growth factor receptor in multiple human tumors. , 1995, Cancer research.
[49] F. Winkler,et al. Observation of an unexpected third receptor molecule in the crystal structure of human interferon-gamma receptor complex. , 2000, Structure.
[50] Christian Wiesmann,et al. Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor , 1999, Nature.
[51] M. Bowman,et al. Crystal structure of the complex of diphtheria toxin with an extracellular fragment of its receptor. , 1997, Molecular cell.
[52] C. Betzel,et al. The secreted form of the epidermal growth factor receptor. Characterization and crystallization of the receptor-ligand complex. , 1990, The Journal of biological chemistry.
[53] B. Kobe,et al. The leucine-rich repeat as a protein recognition motif. , 2001, Current opinion in structural biology.
[54] G. Bricogne,et al. [27] Maximum-likelihood heavy-atom parameter refinement for multiple isomorphous replacement and multiwavelength anomalous diffraction methods. , 1997, Methods in enzymology.
[55] N. Bohr. Atomic Structure , 1921, Nature.
[56] A. Ullrich,et al. Functional analysis of the ligand binding site of EGF‐receptor utilizing chimeric chicken/human receptor molecules. , 1989, The EMBO journal.
[57] A. Burgess,et al. Biochemical characterization of mutant EGF receptors expressed in the hemopoietic cell line BaF/3. , 1998, Growth factors.
[58] R. Jorissen,et al. Characterization of a comparative model of the extracellular domain of the epidermal growth factor receptor , 2008, Protein science : a publication of the Protein Society.