12 Regulation of Protein Synthesis

[1]  I. London,et al.  Fate of reversing factor during restoration of protein synthesis by hemin or GTP in heme-deficient reticulocyte lysates. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[2]  P. Seeburg,et al.  Amino acid sequence of the alpha subunit of transducin deduced from the cDNA sequence. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[3]  H. Khorana,et al.  GTPase of bovine rod outer segments: the amino acid sequence of the alpha subunit as derived from the cDNA sequence. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[4]  H. Suzuki,et al.  Mechanism of stimulation of globin synthesis by adenosine-3',5'-monophosphate and guanosine 5'-triphosphate in a rabbit reticulocyte lysate system. , 1985, Journal of biochemistry.

[5]  A. Dasgupta,et al.  The host protein required for in vitro replication of poliovirus is a protein kinase that phosphorylates eukaryotic initiation factor-2 , 1985, Cell.

[6]  M. Mathews,et al.  Translational control by adenovirus: lack of virus-associated RNAI during adenovirus infection results in phosphorylation of initiation factor eIF-2 and inhibition of protein synthesis. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[7]  K. Manchester Evaluation and significance of kinetic parameters governing function of protein synthesis initiation factors eIF‐2 and eIF‐2B , 1985, FEBS letters.

[8]  M. Mathews,et al.  Regulation of a protein synthesis initiation factor by adenovirus virus-associated RNAI , 1985, Nature.

[9]  J B Hurley,et al.  Homologies between signal transducing G proteins and ras gene products. , 1984, Science.

[10]  I. London,et al.  Distribution of reversing factor in reticulocyte lysates during active protein synthesis and on inhibition by heme deprivation or double-stranded RNA. , 1984, Proceedings of the National Academy of Sciences of the United States of America.

[11]  R. Benne,et al.  Regulation of protein synthesis in eukaryotes. Mode of action of eRF, an eIF-2-recycling factor from rabbit reticulocytes involved in GDP/GTP exchange. , 1984, European journal of biochemistry.

[12]  L. Ovchinnikov,et al.  Endogenous ADP‐ribosylation of elongation factor 2 in polyribosome fraction of rabbit reticulocytes , 1984, FEBS letters.

[13]  M. Wigler,et al.  Structure and activation of the human N-ras gene , 1983, Cell.

[14]  B. Safer 2B or not 2B: Regulation of the catalytic utilization of elF-2 , 1983, Cell.

[15]  I. London,et al.  Effect of phosphorylation of the alpha-subunit of eukaryotic initiation factor 2 on the function of reversing factor in the initiation of protein synthesis. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[16]  T. Hunt,et al.  The use of affinity chromatography on 2'5' ADP-sepharose reveals a requirement for NADPH, thioredoxin and thioredoxin reductase for the maintenance of high protein synthesis activity in rabbit reticulocyte lysates. , 1983, European journal of biochemistry.

[17]  S. Ochoa,et al.  Polypeptide chain initiation in eukaryotes: reversibility of the ternary complex-forming reaction. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[18]  T. Hunt,et al.  The roles of sugar phosphates and thiol-reducing systems in the control of reticulocyte protein synthesis. , 1983, European journal of biochemistry.

[19]  M. Clemens,et al.  Assembly and breakdown of mammalian protein synthesis initiation complexes: regulation by guanine nucleotides and by phosphorylation of initiation factor eIF-2. , 1983, Biochemistry.

[20]  T. Nilsen,et al.  Maintenance of protein synthesis in spite of mRNA breakdown in interferon-treated HeLa cells infected with reovirus , 1983, Molecular and cellular biology.

[21]  W. Kuri-Harcuch,et al.  DNA synthesis and cell division related to adipose differentiation of 3T3 cells , 1983, Journal of cellular physiology.

[22]  I. London,et al.  Effects of skeletal muscle protein phosphatase inhibitor-2 on protein synthesis and protein phosphorylation in rabbit reticulocyte lysates. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[23]  I. London,et al.  Regulation of double-stranded RNA-activated eukaryotic initiation factor 2 alpha kinase by type 2 protein phosphatase in reticulocyte lysates. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[24]  S. L. Holmes,et al.  Interferon action against reovirus: activation of interferon-induced protein kinase in mouse L929 cells upon reovirus infection. , 1982, Virology.

[25]  S. Ochoa,et al.  Mechanism of polypeptide chain initiation in eukaryotes and its control by phosphorylation of the alpha subunit of initiation factor 2. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[26]  I. London,et al.  Regulation of protein synthesis by phosphorylation of eukaryotic initiation factor 2 alpha in intact reticulocytes and reticulocyte lysates. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[27]  M. Clemens,et al.  Phosphorylation inhibits guanine nucleotide exchange on eukaryotic initiation factor 2 , 1982, Nature.

[28]  P. Bornstein,et al.  Regulation of protein synthesis: translational control by procollagen-derived fragments. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[29]  R. Benne,et al.  Initiation of Eukaryotic Protein Synthesis , 1981, Nature.

[30]  I. London,et al.  Relationship between phosphorylation and activity of heme-regulated eukaryotic initiation factor 2 alpha kinase. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[31]  C. Baglioni,et al.  Increased levels of (2'-5')oligo(A) polymerase activity in human lymphoblastoid cells treated with glucocorticoids. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[32]  S. Ochoa,et al.  Purification and properties of the double-stranded RNA-activated eukaryotic initiation factor 3 kinase from rabbit reticulocytes. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[33]  S. Grossberg,et al.  Interferon inhibits the conversion of 3T3-L1 mouse fibroblasts into adipocytes. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[34]  R. S. Ranu,et al.  Regulation of protein synthesis in eukaryotes by the protein kinases that phosphorylate initiation factor eIF‐2 , 1980 .

[35]  I. London,et al.  Site-specific phosphorylation of the α subunit of eukaryotic initiation factor eIF-2 by the heme-regulated and double-stranded RNA-activated eIF-2α kinases from rabbit reticulocyte lysates , 1980 .

[36]  G. Kramer,et al.  Partial purification and characterization of a 90,000-dalton peptide involved in activation of the eIF-2 alpha protein kinase of the hemin-controlled translational repressor. , 1980, Biochemistry.

[37]  I. London,et al.  Characterization of double-stranded-RNA-activated kinase that phosphorylates α subunit of eukaryotic initiation factor 2 (eIF-2α) in reticulocyte lysates , 1980 .

[38]  N. Gupta,et al.  Protein synthesis in rabbit reticulocytes: characteristics of a postribosomal supernatant factor that reverses inhibition of protein synthesis in heme-deficient lysates and inhibition of ternary complex (Met-tRNAfMet.eIF-2.GTP) formation by heme-regulated inhibitor. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[39]  N. Gupta,et al.  Protein synthesis in rabbit reticulocytes: mechanism of protein synthesis inhibition by heme-regulated inhibitor. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[40]  R. Benne,et al.  Purification and characterization of a protein factor that reverses the inhibition of protein synthesis by the heme-regulated translational inhibitor in rabbit reticulocyte lysates. , 1979, European journal of biochemistry.

[41]  William E. Stewart,et al.  The Interferon System , 1979, Springer Vienna.

[42]  C. Baglioni Interferon-induced enzymatic activities and their role in the antiviral state , 1979, Cell.

[43]  B. Hardesty,et al.  Multistep regulatory system for activation of a cyclic AMP-independent eukaryotic initiation factor 2 kinase. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[44]  I. London,et al.  In situ phosphorylation of the alpha subunit of eukaryotic initiation factor 2 in reticulocyte lysates inhibited by heme deficiency, double-stranded RNA, oxidized glutathione, or the heme-regulated protein kinase. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[45]  I. London,et al.  Regulation of protein synthesis in reticulocyte lysates: immune serum inhibits heme-regulated protein kinase activity and differentiates heme-regulated protein kinase from double-stranded RNA-induced protein kinase. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[46]  S. Ochoa,et al.  Further studies on the mode of action of the heme-controlled translational inhibitor. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[47]  G. Stark,et al.  2-5A synthetase: assay, distribution and variation with growth or hormone status , 1979, Nature.

[48]  I. London,et al.  Regulation of protein synthesis in rabbit reticulocyte lysates: additional initiation factor required for formation of ternary complex (eIF-2.GTP.Met-tRNAf) and demonstration of inhibitory effect of heme-regulated protein kinase. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[49]  M. Gross,et al.  Control of protein synthesis by hemin. An association between the formation of the hemin-controlled translational repressor and the phosphorylation of a 100 000 molecular weight protein. , 1978, Biochimica et biophysica acta.

[50]  N. Gupta,et al.  Protein synthesis in rabbit reticulocytes: characteristics of a ribosomal factor that reverses inhibition of protein synthesis in heme-deficient lysates. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[51]  A. Zilberstein,et al.  Isolation of two interferon-induced translational inhibitors: a protein kinase and an oligo-isoadenylate synthetase. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[52]  T. Hunt,et al.  Analysis of phosphorylation of protein synthesis initiation factor eIF-2 by two-dimensional gel electrophoresis. , 1978, European journal of biochemistry.

[53]  I. London,et al.  Inhibition of protein synthesis initiation by oxidized glutathione: activation of a protein kinase that phosphorylates the alpha subunit of eukaryotic initiation factor 2. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[54]  I. London,et al.  Regulation of protein synthesis in rabbit reticulocyte lysates: purification and characterization of heme-reversible translational inhibitor. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[55]  J. Moss,et al.  Isolation of an avian erythrocyte protein possessing ADP-ribosyltransferase activity and capable of activating adenylate cyclase. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[56]  J. Kay,et al.  Inhibition of initiation of protein synthesis in rabbit reticulocyte lysates by a factor present in lymphocyte cytoplasm , 1978, FEBS letters.

[57]  D. Cassel,et al.  Mechanism of cholera toxin action: covalent modification of the guanyl nucleotide-binding protein of the adenylate cyclase system. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[58]  S. Ochoa,et al.  Mode of action of the hemin-controlled inhibitor of protein synthesis: studies with factors from rabbit reticulocytes. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[59]  B. Williams,et al.  Inhibition of cell-free protein synthesis by pppA2′ p5′ A2′ p5′ A: a novel oligonucleotide synthesized by interferon-treated L cell extracts , 1978, Cell.

[60]  I. London,et al.  Regulation of protein synthesis: activation by double-stranded RNA of a protein kinase that phosphorylates eukaryotic initiation factor 2. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[61]  I. London,et al.  Regulation of protein synthesis in rabbit reticulocyte lysates by the heme-regulated protein kinase: inhibition of interaction of Met-tRNAfMet binding factor with another initiation factor in formation of Met-tRNAfMet.40S ribosomal subunit complexes. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[62]  I. London,et al.  Characterization of a rat liver factor that inhibits initiation of protein synthesis in rabbit reticulocyte lysates. , 1977, Proceedings of the National Academy of Sciences of the United States of America.

[63]  G. Matarese,et al.  Inhibition of transcription and translation of globin messenger RNA in dimethyl sulfoxide-stimulated Friend erythroleukemic cells treated with interferon. , 1977, Proceedings of the National Academy of Sciences of the United States of America.

[64]  R. Jackson,et al.  Phosphorylation of initiation factor eIF-2 and the control of reticulocyte protein synthesis , 1977, Cell.

[65]  W. K. Roberts,et al.  Interferon-mediated protein kinase and low-molecular-weight inhibitor of protein synthesis , 1976, Nature.

[66]  I. London,et al.  Regulation of protein synthesis in rabbit reticulocyte lysates: purification and initial characterization of the cyclic 3':5'-AMP independent protein kinase of the heme-regulated translational inhibitor. , 1976, Proceedings of the National Academy of Sciences of the United States of America.

[67]  I. London,et al.  On the mechanism of delayed inhibition of protein synthesis in heme-defecient rabbit reticulocyte lysates. , 1976, Proceedings of the National Academy of Sciences of the United States of America.

[68]  A. Zilberstein,et al.  Specific phosphorylation in vitro of a protein associated with ribosomes of interferon‐treated mouse L cells , 1976, FEBS letters.

[69]  P. Lengyel,et al.  Interferon, double-stranded RNA, and protein phosphorylation. , 1976, Proceedings of the National Academy of Sciences of the United States of America.

[70]  G. Kramer,et al.  Specificity of the protein kinase activity associated with the hemin-controlled repressor of rabbit reticulocyte. , 1976, Proceedings of the National Academy of Sciences of the United States of America.

[71]  I. London,et al.  Regulation of protein synthesis in reticulocyte lysates: phosphorylation of methionyl-tRNAf binding factor by protein kinase activity of translational inhibitor isolated from hemedeficient lysates. , 1976, Proceedings of the National Academy of Sciences of the United States of America.

[72]  I. London,et al.  Control of protein synthesis in reticulocyte lysates: effects of 3':5'-cyclic AMP, ATP, and GTP on inhibitions induced by hemedeficiency, double-stranded RNA, and a reticulocyte translationa inhibitor. , 1976, Proceedings of the National Academy of Sciences of the United States of America.

[73]  G. M. Walton,et al.  Regulation of ternary (Met-tRNAf - GTP - eukaryotic initiation factor 2) protein synthesis initiation complex formation by the adenylate energy charge. , 1976, Biochimica et biophysica acta.

[74]  C Baglioni,et al.  A cell free system from HeLa cells active in initiation of protein synthesis. , 1975, Biochemistry.

[75]  E. Henshaw,et al.  Initiation of protein synthesis in Ehrlich ascites tumour cells. Evidence for physiological variation in the association of methionyl-tRNAf with native 40-S ribosomal subunits in vivo. , 1975, European journal of biochemistry.

[76]  G. M. Walton,et al.  Nucleotide regulation of a eukaryotic protein synthesis initiation complex;. , 1975, Biochimica et biophysica acta.

[77]  S. Liao,et al.  A very rapid effect of androgen on initiation of protein synthesis in prostate. , 1975, Proceedings of the National Academy of Sciences of the United States of America.

[78]  J. Kay,et al.  Initiation of protein synthesis during lymphocyte stimulation , 1974, Nature.

[79]  H. Green,et al.  Sublines of mouse 3T3 cells that accumulate lipid , 1974 .

[80]  I. London,et al.  Effect of hemin on the synthesis of hemoglobin and other proteins in mammalian cells. , 1973, Proceedings of the National Academy of Sciences of the United States of America.

[81]  E. Kosower,et al.  Glutathione. 8. The effects of glutathione disulfide on initiation of protein synthesis. , 1972, Biochimica et biophysica acta.

[82]  M. Mathews,et al.  Further studies on the translation of globin mRNA and encephalomyocarditis virus RNA in a cell-free system from Krebs II ascites cells. , 1972, Biochimica et biophysica acta.

[83]  T. Hunt,et al.  Double-stranded poliovirus RNA inhibits initiation of protein synthesis by reticulocyte lysates. , 1971, Proceedings of the National Academy of Sciences of the United States of America.

[84]  W. Zucker,et al.  Stimulation of globin-chain initiation by hemin in the reticulocyte cell-free system. , 1968, Proceedings of the National Academy of Sciences of the United States of America.

[85]  I. London,et al.  The stimulation of globin synthesis by heme. , 1966, Proceedings of the National Academy of Sciences of the United States of America.

[86]  E. Bermek Mechanisms of Protein Synthesis , 1985, Proceedings in Life Sciences.

[87]  S. Ochoa,et al.  Mechanism of translational control by partial phosphorylation of the alpha subunit of eukaryotic initiation factor 2. , 1984, Proceedings of the National Academy of Sciences of the United States of America.

[88]  P. Lengyel Biochemistry of interferons and their actions. , 1982, Annual review of biochemistry.

[89]  L. W. Mozes Cellular Responses to Molecular Modulators , 1981 .

[90]  W. Anderson,et al.  The regulation of initiation of mammalian protein synthesis. , 1981, Progress in nucleic acid research and molecular biology.

[91]  S. Ochoa,et al.  Mode of action of the heme-controlled translational inhibitor: relationship of eukaryotic initiation factor 2-stimulating protein to translation restoring factor. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[92]  S. Ochoa,et al.  Mode of action of the hemin-controlled inhibitor of protein synthesis. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[93]  H. Trachsel,et al.  Binding and release of eukaryotic initiation factor eIF-2 and GTP during protein synthesis initiation. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[94]  I. Kerr,et al.  pppA2'p5'A2'p5'A: an inhibitor of protein synthesis synthesized with an enzyme fraction from interferon-treated cells. , 1978, Proceedings of the National Academy of Sciences of the United States of America.