Benzene poisoning, a risk factor for hematological malignancy, is associated with the NQO1 609C-->T mutation and rapid fractional excretion of chlorzoxazone.
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Xi | Liqiang | R. Hayes | N. Rothman | S. Wacholder | M. Dosemeci | Luoping Zhang | Martyn T. Smith | D. Ross | K. Meyer | B. Hoener | M. Linet | S. Yin | W. Lu | G. Li | J. T. Stewart | N. Rothman | Rothman | L. Zhang | M. Smith | S. Campleman | Guilan Li | N. Titenko-Holland | L. Xi | R. Hayes | James | R. Traver | Sholom | Wacholder | Kathleen | Campleman | Songnian | Luoping | James T. Stewart | Dosemeci | Li | Zhang | Wei Lu | Nathaniel | Martyn | T. Smith | Richard | B. Hayes | Robert | D. Traver | Betty-ann | Hoener | Sharan | Gui-lan | Mustafa | Martha | Linet | Kathleen | B. Meyer | T. Stewart | Yin | T. Smith
[1] D. Liebler,et al. The Reduction of α-Tocopherolquinone by Human NAD(P)H:Quinone Oxidoreductase: The Role of α-Tocopherolhydroquinone as a Cellular Antioxidant , 1997 .
[2] D. Ross,et al. Characterization of a polymorphism in NAD(P)H: quinone oxidoreductase (DT-diaphorase). , 1997, British Journal of Cancer.
[3] L. Landi,et al. The role of DT-diaphorase in the maintenance of the reduced antioxidant form of coenzyme Q in membrane systems. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[4] M Dosemeci,et al. Hematotoxicity among Chinese workers heavily exposed to benzene. , 1996, American journal of industrial medicine.
[5] K. Korzekwa,et al. Inhibitory and noninhibitory monoclonal antibodies to human cytochrome P450 2E1. , 1996, Chemical research in toxicology.
[6] A. Dreisbach,et al. Urinary excretion of 6‐hydroxychlorzoxazone as an index of CYP2E1 activity , 1995, Clinical pharmacology and therapeutics.
[7] K. Buetow,et al. Identification of an NAD(P)H:quinone oxidoreductase polymorphism and its association with lung cancer and smoking. , 1995, Pharmacogenetics.
[8] F. Gonzalez,et al. Chlorzoxazone is metabolized by human CYP1A2 as well as by human CYP2E1. , 1995, Pharmacogenetics.
[9] E. Vesell,et al. Studies on interindividual variations of CYP2E1 using chlorzoxazone as an in vivo probe. , 1995, Pharmacogenetics.
[10] S. Horie,et al. Variability in the disposition of chlorzoxazone , 1994, Biopharmaceutics & drug disposition.
[11] R. Hayes,et al. Cohort study among workers exposed to benzene in China: II. Exposure assessment. , 1994, American journal of industrial medicine.
[12] K. Kawajiri,et al. Different regulation and expression of the human CYP2E1 gene due to the RsaI polymorphism in the 5'-flanking region. , 1994, Journal of biochemistry.
[13] W. Schulz,et al. Loss of heterozygosity at the NAD(P)H: quinone oxidoreductase locus associated with increased resistance against mitomycin C in a human bladder carcinoma cell line. , 1994, Biological chemistry Hoppe-Seyler.
[14] J. Fraumeni,et al. Hematopoietic malignancies and related disorders among benzene-exposed workers in China. , 1994, Leukemia & lymphoma.
[15] A. Guillouzo,et al. Both cytochromes P450 2E1 and 1A1 are involved in the metabolism of chlorzoxazone. , 1993, Chemical research in toxicology.
[16] K. Danenberg,et al. NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity. , 1992, Cancer research.
[17] K. Kawajiri,et al. Genetic Polymorphisms in the 5 '-Flanking Region Change Transcriptional Regulation of the Human Cytochrome P 45011 E 1 Gene ' , 2008 .
[18] P. Beaune,et al. Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P-450IIE1. , 1991, Chemical research in toxicology.
[19] P. Beaune,et al. Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P-450IIE1 , 1990 .
[20] R. Novak,et al. Evidence for increased translational efficiency in the induction of P450IIE1 by solvents: analysis of P450IIE1 mRNA polyribosomal distribution. , 1990, Biochemical and biophysical research communications.
[21] D. Eastmond,et al. Peroxidase-dependent metabolism of benzene's phenolic metabolites and its potential role in benzene toxicity and carcinogenicity. , 1989, Environmental health perspectives.
[22] D. Koop,et al. Identification of ethanol-inducible P450 isozyme 3a (P450IIE1) as a benzene and phenol hydroxylase. , 1989, Toxicology and applied pharmacology.
[23] R D Irons,et al. An interaction of benzene metabolites reproduces the myelotoxicity observed with benzene exposure. , 1987, Toxicology and applied pharmacology.
[24] G F Kalf,et al. Recent advances in the metabolism and toxicity of benzene. , 1987, Critical reviews in toxicology.