Cadmium dynamics in fish: pulse studies with 109Cd in female zebrafish, Brachydanio rerio

The dynamics of a subtoxic pulse of non-dietary 109Cd was followed for up to 304 days after the exposure period in female zebrafish. The retention of dietary 109Cd was also estimated. The distribution of 109Cd was studied by autoradiography, whole-body analysis and tissue sampling. After exposure to non-dietary 109Cd for 10 days there was a rapid loss of 109Cd from the gills. The 109Cd content of the alimentary canal exceeded that which could have been expected from normal drinking. Based on the distribution pattern of non-dietary 109Cd in tissues, two groups of tissues were distinguished: (i) the gills, alimentary canal and heart which showed maximum 109Cd values directly after exposure, followed by a pronounced decrease up to day 21; (ii) the liver, kidney, ovary and muscle, in which there was a delay in maximum 109Cd activity to days 21–42, with subsequent loss. Small amounts of 109Cd were noted in fry and fertilized eggs originating from zebrafish exposed to non-dietary 109Cd. After exposure to dietary 109Cd, less than 5% was retained in the zebrafish body, mainly in the alimentary canal.

[1]  D. Pascoe,et al.  Cadmium uptake and distribution in sticklebacks related to the concentration and method of exposure. , 1983, Ecotoxicology and environmental safety.

[2]  J. Ferrante,et al.  Pathology of lethal and sublethal exposure of fathead minnows, pimephales promelas, to cadmium: A model for aquatic toxicity assessment , 1983 .

[3]  E. Bock,et al.  Identification of fetuin in human and rat fetuses and in other species. , 1983, Comparative biochemistry and physiology. A, Comparative physiology.

[4]  Ȧ. Larsson,et al.  Disturbed ion balance in flounder, Platichthys flesus L. exposed to sublethal levels of cadmium , 1981 .

[5]  W. Hawkins,et al.  Acute effects of cadmium on the spot Leiostomus xanthurus (Teleostei): tissue distribution and renal ultrastructure. , 1980, Journal of toxicology and environmental health.

[6]  D. Calamari,et al.  Influence of water hardness on cadmium toxicity to Salmo gairdneri rich. , 1980 .

[7]  S. Kimura,et al.  Accumulation and biological effects of cadmium in rainbow trout. , 1980 .

[8]  J. Carroll,et al.  Influences of hardness constituents on the acute toxicity of cadmium to brook trout (Salvelinus fontinalis) , 1979, Bulletin of environmental contamination and toxicology.

[9]  M. Johansson-Sjöbeck,et al.  The effect of cadmium on the hematology and on the activity of delta-aminolevulinic acid dehydratase (ALA-D) in blood and hematopoietic tissues of the flounder, Pleuronectes flesus L. , 1978, Environmental research.

[10]  W. Sunda,et al.  Effect of chemical speciation on toxicity of cadmium to grass shrimp, Palaemonetes pugio: importance of free cadmium ion , 1978 .

[11]  U. Varanasi,et al.  Uptake and release of lead and cadmium in skin and mucus of coho salmon (Oncorhynchus kisutch). , 1978, Comparative biochemistry and physiology. C: Comparative pharmacology.

[12]  R. Pentreath.  The accumulation of cadmium by the plaice, Pleuronectes platessa L. and the thornback ray, Raja clavata L , 1977 .

[13]  R. Rehwoldt,et al.  Uptake and effect of cadmium on zebrafish , 1976, Bulletin of environmental contamination and toxicology.

[14]  P. Yevich,et al.  Histological and toxicological responses of the mummichog, Fundulus Heteroclitus (L.) to combinations of levels of cadmium and dissolved oxygen in a freshwater , 1975 .

[15]  R. Eisler.  Radiocadmium exchange with seawater by Fundulus heteroclitus (L.) (Pisces: Cyprinodontidae) , 1974 .

[16]  Q. Pickering,et al.  Acute and Chronic Toxicity of Cadmium to the Fathead Minnow (Pimephales promelas) , 1972 .

[17]  P. Yevich,et al.  Histological and Hematological Responses of an Estuarine Teleost to Cadmium , 1970 .