A proof of concept for targeting the PrPC - Amyloid β peptide interaction in basal prostate cancer and mesenchymal colon cancer
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P. Laurent-Puig | N. Vodovar | J. Launay | A. de Reyniès | D. Le Corre | S. Martin-Lannerée | S. Mouillet-Richard | F. Djouadi | C. Pilati | T. Hirsch | M. Sroussi | Alexandre Ghazi | S. Martin‐Lannerée
[1] B. de Strooper,et al. The amyloid hypothesis in Alzheimer disease: new insights from new therapeutics , 2022, Nature Reviews Drug Discovery.
[2] S. Hornemann,et al. Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies , 2021, Science advances.
[3] P. Laurent-Puig,et al. The Cellular Prion Protein and the Hallmarks of Cancer , 2021, Cancers.
[4] P. Laurent-Puig,et al. Prognostic value of the PrPC-ILK-IDO1 axis in the mesenchymal colorectal cancer subtype , 2021, Oncoimmunology.
[5] B. de Strooper,et al. The β-Secretase BACE1 in Alzheimer’s Disease , 2020, Biological Psychiatry.
[6] Kelly V. Ruggles,et al. Melanoma-secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis , 2019, bioRxiv.
[7] P. Laurent-Puig,et al. The cellular prion protein controls the mesenchymal-like molecular subtype and predicts disease outcome in colorectal cancer , 2019, EBioMedicine.
[8] K. Qin,et al. “Dual Disease” TgAD/GSS mice exhibit enhanced Alzheimer’s disease pathology and reveal PrPC-dependent secretion of Aβ , 2019, Scientific Reports.
[9] L. Magnani,et al. Dickkopf-3 links HSF1 and YAP/TAZ signalling to control aggressive behaviours in cancer-associated fibroblasts , 2019, Nature Communications.
[10] A. Villers,et al. Comprehensive molecular classification of localized prostate adenocarcinoma reveals a tumour subtype predictive of non-aggressive disease , 2018, Annals of oncology : official journal of the European Society for Medical Oncology.
[11] K. Kirshenbaum,et al. Anti-prion Protein Antibody 6D11 Restores Cellular Proteostasis of Prion Protein Through Disrupting Recycling Propagation of PrPSc and Targeting PrPSc for Lysosomal Degradation , 2018, Molecular Neurobiology.
[12] Menggang Yu,et al. Associations of Luminal and Basal Subtyping of Prostate Cancer With Prognosis and Response to Androgen Deprivation Therapy , 2017, JAMA oncology.
[13] Yiling Lu,et al. Characterization of Human Cancer Cell Lines by Reverse-phase Protein Arrays. , 2017, Cancer cell.
[14] N. Hooper,et al. Ablation of Prion Protein in Wild Type Human Amyloid Precursor Protein (APP) Transgenic Mice Does Not Alter The Proteolysis of APP, Levels of Amyloid-β or Pathologic Phenotype , 2016, PloS one.
[15] S. Stewart,et al. Dickkopf-related protein 1 (Dkk1) regulates the accumulation and function of myeloid derived suppressor cells in cancer , 2016, The Journal of experimental medicine.
[16] Yue Lu,et al. Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer , 2016, Nature Communications.
[17] Joshua M. Stuart,et al. A basal stem cell signature identifies aggressive prostate cancer phenotypes , 2015, Proceedings of the National Academy of Sciences.
[18] Jeffrey S. Morris,et al. The Consensus Molecular Subtypes of Colorectal Cancer , 2015, Nature Medicine.
[19] M. Verbeek,et al. Dickkopf‐related protein 3 is a potential Aβ‐associated protein in Alzheimer's Disease , 2015, Journal of neurochemistry.
[20] Andreas Heger,et al. Next-generation Sequencing of Advanced Prostate Cancer Treated with Androgen-deprivation Therapy , 2014, European urology.
[21] S. Love,et al. Prion Protein Is Decreased in Alzheimer's Brain and Inversely Correlates with BACE1 Activity, Amyloid-β Levels and Braak Stage , 2013, PloS one.
[22] G. Breen,et al. Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt–PCP–JNK pathway , 2012, Molecular Psychiatry.
[23] Josephine A. Wright,et al. Prion protein expression alters APP cleavage without interaction with BACE-1 , 2012, Neurochemistry International.
[24] Adam A. Margolin,et al. The Cancer Cell Line Encyclopedia enables predictive modeling of anticancer drug sensitivity , 2012, Nature.
[25] N. Hooper,et al. Prion Protein Interacts with BACE1 Protein and Differentially Regulates Its Activity toward Wild Type and Swedish Mutant Amyloid Precursor Protein* , 2011, The Journal of Biological Chemistry.
[26] Adriano Aguzzi,et al. Prions: protein aggregation and infectious diseases. , 2009, Physiological reviews.
[27] David R. Brown,et al. The effects of prion protein expression on metal metabolism , 2009, Molecular and Cellular Neuroscience.
[28] G. Zamponi. Faculty Opinions recommendation of Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers. , 2009 .
[29] John W. Gilbert,et al. Cellular Prion Protein Mediates Impairment of Synaptic Plasticity by Amyloid-β Oligomers , 2009, Nature.
[30] N. Hooper,et al. Cellular prion protein regulates β-secretase cleavage of the Alzheimer's amyloid precursor protein , 2007, Proceedings of the National Academy of Sciences.
[31] J. Laplanche,et al. Signal transduction through prion protein. , 2000, Science.
[32] S. Martin-Lannerée,et al. Functions of the Prion Protein. , 2017, Progress in molecular biology and translational science.