Interaction of Dihydromyricetin and α-Amylase

The interaction of dihydromyricetin (DMY) and α-amylase was investigated. The complex formed between DMY and α-amylase resulted in decreased antioxidant activity of DMY and the catalytic activity of the enzyme, as well as efficient quenching of the intrinsic fluorescence of α-amylase. An α-amylase molecule provides one binding site for a DMY molecule. These results will be useful for exploiting this compound to combat diseases efficiently.

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