Combination of a Big Data Analytics Resource System With an Artificial Intelligence Algorithm to Identify Clinically Actionable Radiation Dose Thresholds for Dysphagia in Head and Neck Patients

[1]  Christopher U. Jones,et al.  Radiotherapy plus cetuximab or cisplatin in human papillomavirus-positive oropharyngeal cancer (NRG Oncology RTOG 1016): a randomised, multicentre, non-inferiority trial , 2019, The Lancet.

[2]  D Ruan,et al.  Treatment data and technical process challenges for practical big data efforts in radiation oncology , 2018, Medical physics.

[3]  Mona Kamal,et al.  Radiotherapy dose-volume parameters predict videofluoroscopy-detected dysphagia per DIGEST after IMRT for oropharyngeal cancer: Results of a prospective registry. , 2018, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[4]  Randall K. Ten Haken,et al.  Big Data in Designing Clinical Trials: Opportunities and Challenges , 2017, Front. Oncol..

[5]  D. Fried,et al.  Dosimetric Predictors of Patient-Reported Xerostomia and Dysphagia With Deintensified Chemoradiation Therapy for HPV-Associated Oropharyngeal Squamous Cell Carcinoma. , 2017, International journal of radiation oncology, biology, physics.

[6]  James M. Balter,et al.  Incorporating big data into treatment plan evaluation: Development of statistical DVH metrics and visualization dashboards , 2017, Advances in radiation oncology.

[7]  Issam El Naqa,et al.  The big data effort in radiation oncology: Data mining or data farming? , 2016, Advances in radiation oncology.

[8]  F. Alongi,et al.  Dose-volume-related dysphagia after constrictor muscles definition in head and neck cancer intensity-modulated radiation treatment. , 2014, The British journal of radiology.

[9]  Randall K Ten Haken,et al.  Chemo-IMRT of oropharyngeal cancer aiming to reduce dysphagia: swallowing organs late complication probabilities and dosimetric correlates. , 2011, International journal of radiation oncology, biology, physics.

[10]  Xavier Robin,et al.  pROC: an open-source package for R and S+ to analyze and compare ROC curves , 2011, BMC Bioinformatics.

[11]  Jimmy J Caudell,et al.  Dosimetric factors associated with long-term dysphagia after definitive radiotherapy for squamous cell carcinoma of the head and neck. , 2010, International journal of radiation oncology, biology, physics.

[12]  F. Feng,et al.  Intensity-modulated radiotherapy of head and neck cancer aiming to reduce dysphagia: early dose-effect relationships for the swallowing structures. , 2007, International journal of radiation oncology, biology, physics.

[13]  W. Jackson,et al.  Contribution : Submandibular gland sparing when irradiating neck level IB in the treatment of oral squamous cell carcinoma , 2018 .

[14]  Ying Xiao,et al.  American Association of Physicists in Medicine Task Group 263: Standardizing Nomenclatures in Radiation Oncology , 2017, International journal of radiation oncology, biology, physics.

[15]  R Core Team,et al.  R: A language and environment for statistical computing. , 2014 .

[16]  Andy Liaw,et al.  Classification and Regression by randomForest , 2007 .