Successful induction of sclerostin in human-derived fibroblasts by 4 transcription factors and its regulation by parathyroid hormone, hypoxia, and prostaglandin E2.
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Wei Wang | Yasuji Kitabatake | D. Okuzaki | K. Ozono | T. Kubota | T. Michigami | N. Namba | Yasuji Kitabatake | Daisuke Okuzaki | Makoto Fujiwara | Takuo Kubota | Yasuhisa Ohata | Kohji Miura | Taichi Kitaoka | Noriyuki Namba | Toshimi Michigami | Keiichi Ozono | Y. Ohata | T. Kitaoka | M. Fujiwara | Kohji Miura | Wei Wang
[1] J. Riancho,et al. Role of BMPs in the regulation of sclerostin as revealed by an epigenetic modifier of human bone cells , 2013, Molecular and Cellular Endocrinology.
[2] Zhiyu Zhou,et al. HIF-1α Inhibits Wnt Signaling Pathway by Activating Sost Expression in Osteoblasts , 2013, PloS one.
[3] Cesar Libanati,et al. Romosozumab in postmenopausal women with low bone mineral density , 2014, The New England journal of medicine.
[4] Matthew R Allen,et al. Mechanical Stimulation of Bone in Vivo Reduces Osteocyte Expression of Sost/Sclerostin* , 2008, Journal of Biological Chemistry.
[5] F. Natt,et al. Control of the SOST Bone Enhancer by PTH Using MEF2 Transcription Factors , 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[6] M. Kneissel,et al. SOST is a target gene for PTH in bone. , 2005, Bone.
[7] F M Maciel,et al. Induction of cyclooxygenase-2 by parathyroid hormone in human osteoblasts in culture. , 1997, The Journal of rheumatology.
[8] P. Pietschmann,et al. Serum sclerostin levels are decreased in adult patients with different types of osteogenesis imperfecta. , 2014, The Journal of clinical endocrinology and metabolism.
[9] J. Latham,et al. Unique regulation of SOST, the sclerosteosis gene, by BMPs and steroid hormones in human osteoblasts. , 2004, Bone.
[10] B. de Crombrugghe,et al. Sclerostin is a direct target of osteoblast-specific transcription factor osterix. , 2010, Biochemical and biophysical research communications.
[11] G. Loots,et al. TGF-β regulates sclerostin expression via the ECR5 enhancer. , 2012, Bone.
[12] H. Egusa,et al. Krüppel-like factor 4 regulates membranous and endochondral ossification. , 2012, Experimental cell research.
[13] Y. Mishina,et al. BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway , 2008, Development.
[14] I. D. Padhi,et al. Serum sclerostin levels negatively correlate with parathyroid hormone levels and free estrogen index in postmenopausal women. , 2010, The Journal of clinical endocrinology and metabolism.
[15] O. Leupin,et al. Does osteocytic SOST suppression mediate PTH bone anabolism? , 2010, Trends in Endocrinology & Metabolism.
[16] F. Glorieux,et al. Circulating sclerostin in children and young adults with heritable bone disorders. , 2014, The Journal of clinical endocrinology and metabolism.
[17] Gabriela G. Loots,et al. Prostaglandin E2 Signals Through PTGER2 to Regulate Sclerostin Expression , 2011, PloS one.
[18] D. B. Burr,et al. Suppression of Prostaglandin Synthesis with NS-398 Has Different Effects on Endocortical and Periosteal Bone Formation Induced by Mechanical Loading , 2002, Calcified Tissue International.
[19] Tsonwin Hai,et al. ATF3, a hub of the cellular adaptive-response network, in the pathogenesis of diseases: is modulation of inflammation a unifying component? , 2010, Gene expression.
[20] M. Fraga,et al. DNA methylation contributes to the regulation of sclerostin expression in human osteocytes , 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[21] A. Evdokiou,et al. Pro‐Inflammatory Cytokines TNF‐Related Weak Inducer of Apoptosis (TWEAK) and TNFα Induce the Mitogen‐Activated Protein Kinase (MAPK)‐Dependent Expression of Sclerostin in Human Osteoblasts , 2009, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[22] Jianhua Ruan,et al. A systems biology approach to the identification and analysis of transcriptional regulatory networks in osteocytes , 2009, BMC Bioinformatics.
[23] A. Javed,et al. Genetic and transcriptional control of bone formation. , 2010, Oral and maxillofacial surgery clinics of North America.
[24] Lance E. Lanyon,et al. Sost down-regulation by mechanical strain in human osteoblastic cells involves PGE2 signaling via EP4 , 2011, FEBS letters.
[25] John G Doench,et al. HDAC5 Controls MEF2C‐Driven Sclerostin Expression in Osteocytes , 2015, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[26] Guoyin Feng,et al. Sclerostin Mediates Bone Response to Mechanical Unloading Through Antagonizing Wnt/β‐Catenin Signaling , 2009, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[27] B. Riggs,et al. Regulation of Circulating Sclerostin Levels by Sex Steroids in Women and in Men , 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[28] J. Deng,et al. The Novel Zinc Finger-Containing Transcription Factor Osterix Is Required for Osteoblast Differentiation and Bone Formation , 2002, Cell.
[29] M. Forwood,et al. Inducible cyclo‐oxygenase (COX‐2) mediates the induction of bone formation by mechanical loading in vivo , 1996, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[30] J. Boudreaux,et al. Synergistic Induction of Osteocalcin Gene Expression , 1996, The Journal of Biological Chemistry.
[31] G. Loots,et al. Hypoxia decreases sclerostin expression and increases Wnt signaling in osteoblasts , 2010, Journal of cellular biochemistry.
[32] Seongsoo Hwang,et al. ER stress-inducible ATF3 suppresses BMP2-induced ALP expression and activation in MC3T3-E1 cells. , 2014, Biochemical and biophysical research communications.
[33] Andreas Krämer,et al. Causal analysis approaches in Ingenuity Pathway Analysis , 2013, Bioinform..
[34] S. Yamanaka,et al. Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors , 2006, Cell.