Clinicopathologic Features of Non-Small-Cell Lung Cancer with EML4–ALK Fusion Gene
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A. Yoshizawa | M. Sonobe | T. Manabe | H. Date | Tsuyoshi Takahashi | T. Menju | K. Okubo | R. Miyahara | Masashi Kobayashi | E. Nakayama | Shotaro Iwakiri | N. Mino | Kiyoshi Sato
[1] A. Sihoe,et al. The EML4‐ALK fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild‐type EGFR and KRAS , 2009, Cancer.
[2] Gaetano Rocco,et al. Gefitinib in Non Small Cell Lung Cancer , 2011, Journal of biomedicine & biotechnology.
[3] Yuki Togashi,et al. Identification of novel isoforms of the EML4-ALK transforming gene in non-small cell lung cancer. , 2008, Cancer research.
[4] P. Baas,et al. Gefitinib as a last treatment option for non-small-cell lung cancer: durable disease control in a subset of patients. , 2004, Annals of oncology : official journal of the European Society for Medical Oncology.
[5] S. Gabriel,et al. EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy , 2004, Science.
[6] Y. Yatabe,et al. Mutations of the epidermal growth factor receptor gene and related genes as determinants of epidermal growth factor receptor tyrosine kinase inhibitors sensitivity in lung cancer , 2007, Cancer science.
[7] A. Marchetti,et al. EGFR mutations in non-small-cell lung cancer: analysis of a large series of cases and development of a rapid and sensitive method for diagnostic screening with potential implications on pharmacologic treatment. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[8] M. Sonobe,et al. Lung adenocarcinoma harboring mutations in the ERBB2 kinase domain. , 2006, The Journal of molecular diagnostics : JMD.
[9] T. Utsunomiya,et al. EML4–ALK fusion transcript is not found in gastrointestinal and breast cancers , 2008, British Journal of Cancer.
[10] R. Wilson,et al. EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[11] Francesca Demichelis,et al. EML4-ALK fusion lung cancer: a rare acquired event. , 2008, Neoplasia.
[12] Y. Ishikawa,et al. A mouse model for EML4-ALK-positive lung cancer , 2008, Proceedings of the National Academy of Sciences.
[13] Xiao Chen,et al. Identification of EGFR kinase domain mutations among lung cancer patients in China: implication for targeted cancer therapy , 2005, Cell Research.
[14] S. Kudoh,et al. Multicentre prospective phase II trial of gefitinib for advanced non-small cell lung cancer with epidermal growth factor receptor mutations: results of the West Japan Thoracic Oncology Group trial (WJTOG0403) , 2008, British Journal of Cancer.
[15] 園部 誠. Mutations in the epidermal growth factor receptor gene are linked to smoking-independent, lung adenocarcinoma , 2006 .
[16] H. Sugimura,et al. EML4-ALK fusion transcripts, but no NPM-, TPM3-, CLTC-, ATIC-, or TFG-ALK fusion transcripts, in non-small cell lung carcinomas. , 2008, Lung cancer.
[17] Andrew D. Yates,et al. Athletics: Momentous sprint at the 2156 Olympics? , 2004, Nature.
[18] Y. Yamashita,et al. K-ras gene mutations in non-small cell lung cancer in Japanese. , 2000, Oncology Report.
[19] H. Sasaki,et al. EGFR and erbB2 mutation status in Japanese lung cancer patients , 2006, International journal of cancer.
[20] M. Sonobe,et al. Mutations in the epidermal growth factor receptor gene are linked to smoking-independent, lung adenocarcinoma , 2005, British Journal of Cancer.
[21] Takayuki Kosaka,et al. Mutations of the Epidermal Growth Factor Receptor Gene in Lung Cancer , 2004, Cancer Research.
[22] Hyae-Young Kim,et al. The Role of Gefitinib Treatment for Korean Never-Smokers with Advanced or Metastatic Adenocarcinoma of the Lung: A Prospective Study , 2006, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
[23] J. Garst,et al. Epidermal growth factor receptor inhibitors and their role in non-small-cell lung cancer , 2005, Current oncology reports.
[24] E. Campo,et al. EML4-ALK rearrangement in non-small cell lung cancer and non-tumor lung tissues. , 2009, The American journal of pathology.
[25] Takayuki Kosaka,et al. Mutations of the epidermal growth factor receptor gene predict prolonged survival after gefitinib treatment in patients with non-small-cell lung cancer with postoperative recurrence. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[26] T. Kurth,et al. The safety and efficacy of gefitinib versus platinum-based doublets chemotherapy as the first-line treatment for advanced non-small-cell lung cancer patients in East Asia: a meta-analysis. , 2008, Lung cancer.
[27] T. Mitsudomi,et al. Mutations in the epidermal growth factor receptor gene and effects of EGFR-tyrosine kinase inhibitors on lung cancers , 2008, General thoracic and cardiovascular surgery.
[28] Mayumi Ono,et al. Activating Mutations in the Tyrosine Kinase Domain of the Epidermal Growth Factor Receptor Are Associated with Improved Survival in Gefitinib-Treated Chemorefractory Lung Adenocarcinomas , 2005, Clinical Cancer Research.
[29] T. Mok,et al. Epidermal Growth Factor Receptor Mutations and Their Correlation with Gefitinib Therapy in Patients with Non-small Cell Lung Cancer: A Meta-Analysis Based on Updated Individual Patient Data from Six Medical Centers in Mainland China , 2007, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
[30] Y. Ohe,et al. EGFR mutations predict survival benefit from gefitinib in patients with advanced lung adenocarcinoma: a historical comparison of patients treated before and after gefitinib approval in Japan. , 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[31] Y. Ishikawa,et al. Multiplex Reverse Transcription-PCR Screening for EML4-ALK Fusion Transcripts , 2008, Clinical Cancer Research.
[32] M. Spitz,et al. Clinicopathologic Characteristics of the EGFR Gene Mutation in Non–small Cell Lung Cancer , 2006, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
[33] Yuki Togashi,et al. EML4-ALK Fusion Is Linked to Histological Characteristics in a Subset of Lung Cancers , 2008, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
[34] Y. Ishikawa,et al. KIF5B-ALK, a Novel Fusion Oncokinase Identified by an Immunohistochemistry-based Diagnostic System for ALK-positive Lung Cancer , 2009, Clinical Cancer Research.
[35] Hai-sheng Zhou,et al. Gefitinib-Sensitive Mutations of the Epidermal Growth Factor Receptor Tyrosine Kinase Domain in Chinese Patients with Non–Small Cell Lung Cancer , 2005, Clinical Cancer Research.
[36] H. Aburatani,et al. Identification of the transforming EML4–ALK fusion gene in non-small-cell lung cancer , 2007, Nature.
[37] Keunchil Park,et al. A review of the benefit–risk profile of gefitinib in Asian patients with advanced non‐small‐cell lung cancer , 2006, Current medical research and opinion.
[38] Shih-Feng Tsai,et al. High Frequency of Epidermal Growth Factor Receptor Mutations with Complex Patterns in Non–Small Cell Lung Cancers Related to Gefitinib Responsiveness in Taiwan , 2004, Clinical Cancer Research.
[39] S. Hirohashi,et al. Gene expression profiling of epidermal growth factor receptor/KRAS pathway activation in lung adenocarcinoma , 2007, Cancer science.
[40] J. Minna,et al. Somatic mutations of the HER2 kinase domain in lung adenocarcinomas. , 2005, Cancer research.
[41] M. Sonobe,et al. Influence of epidermal growth factor receptor (EGFR) gene mutations on the expression of EGFR, phosphoryl‐Akt, and phosphoryl‐MAPK, and on the prognosis of patients with non‐small cell lung cancer , 2007, Journal of surgical oncology.
[42] N. Hanna,et al. EGF Receptor Gene Mutations Are Common in Lung Cancers From “Never Smokers” and Are Associated With Sensitivity of Tumors to Gefitinib and Erlotinib , 2006 .
[43] Derek Y. Chiang,et al. EML4-ALK Fusion Gene and Efficacy of an ALK Kinase Inhibitor in Lung Cancer , 2008, Clinical Cancer Research.
[44] Y. Ishikawa,et al. EML4-ALK lung cancers are characterized by rare other mutations, a TTF-1 cell lineage, an acinar histology, and young onset , 2009, Modern Pathology.
[45] C. Chiu,et al. Gefitinib as front-line treatment in Chinese patients with advanced non-small-cell lung cancer. , 2006, Lung cancer.