Racial / Ethnic Disparities in ART Adherence in the United States : Findings From the MACH 14 Study

Methods: Individual-level data were pooled from 13 US-based studies employing electronic drug monitoring to assess adherence. Adherence was operationalized as percent of prescribed doses taken from the first 12 (monthly) waves of data in each study. Depression symptoms were aggregated from several widely used assessments, and substance use was operationalized as any use of cocaine/ stimulants, heroin/opiates, ecstasy, hallucinogens, or sedatives in the 30–365 days preceding baseline.

[1]  Brian P. Flaherty,et al.  Optimizing the Analysis of Adherence Interventions Using Logistic Generalized Estimating Equations , 2012, AIDS and Behavior.

[2]  Richard D Moore,et al.  The role of cultural distance between patient and provider in explaining racial/ethnic disparities in HIV care. , 2011, Patient education and counseling.

[3]  R. Remien,et al.  A Closer Look at Depression and Its Relationship to HIV Antiretroviral Adherence , 2011, Annals of behavioral medicine : a publication of the Society of Behavioral Medicine.

[4]  Wayne T. Steward,et al.  Psychiatric Risk Factors for HIV Disease Progression: The Role of Inconsistent Patterns of Antiretroviral Therapy Utilization , 2011, Journal of acquired immune deficiency syndromes.

[5]  R. Rothman,et al.  Numeracy Skills Explain Racial Differences in HIV Medication Management , 2010, AIDS and Behavior.

[6]  Frank H. Galvan,et al.  Longitudinal Relationships Between Antiretroviral Treatment Adherence and Discrimination Due to HIV-Serostatus, Race, and Sexual Orientation Among African–American Men with HIV , 2010, Annals of behavioral medicine : a publication of the Society of Behavioral Medicine.

[7]  Frank H. Galvan,et al.  Conspiracy Beliefs About HIV Are Related to Antiretroviral Treatment Nonadherence Among African American Men With HIV , 2009, Journal of acquired immune deficiency syndromes.

[8]  R. Detels,et al.  Evaluation of Adherence and Factors Affecting Adherence to Combination Antiretroviral Therapy Among White, Hispanic, and Black Men in the MACS Cohort , 2009, Journal of acquired immune deficiency syndromes.

[9]  F. Altice,et al.  Depression and symptomatic response among HIV-infected drug users enrolled in a randomized controlled trial of directly administered antiretroviral therapy , 2009, AIDS care.

[10]  M. Horberg,et al.  Race/Ethnicity and Risk of AIDS and Death Among HIV-infected Patients with Access to Care , 2009, Journal of General Internal Medicine.

[11]  R. Durán,et al.  Latinos and HIV/AIDS: Examining Factors Related to Disparity and Identifying Opportunities for Psychosocial Intervention Research , 2009, AIDS and Behavior.

[12]  H. Myers.  Ethnicity- and socio-economic status-related stresses in context: an integrative review and conceptual model , 2009, Journal of Behavioral Medicine.

[13]  C. Zimmer,et al.  Discrimination, Distrust, and Racial/Ethnic Disparities in Antiretroviral Therapy Adherence Among a National Sample of HIV-Infected Patients , 2008, Journal of acquired immune deficiency syndromes.

[14]  P. Halkitis,et al.  Analysis of HIV medication adherence in relation to person and treatment characteristics using hierarchical linear modeling. , 2008, AIDS patient care and STDs.

[15]  M. Mugavero,et al.  The Influence of Psychosocial Characteristics and Race/Ethnicity on the Use, Duration, and Success of Antiretroviral Therapy , 2008, Journal of acquired immune deficiency syndromes.

[16]  Stephen J Gange,et al.  Patterns and predictors of changes in adherence to highly active antiretroviral therapy: longitudinal study of men and women. , 2007, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[17]  M. Wolf,et al.  Health literacy: an overlooked factor in understanding HIV health disparities. , 2007, American journal of preventive medicine.

[18]  P. Sullivan,et al.  Patient and Regimen Characteristics Associated with Self-Reported Nonadherence to Antiretroviral Therapy , 2007, PloS one.

[19]  D. W. Sue,et al.  Racial microaggressions in everyday life: implications for clinical practice. , 2007, The American psychologist.

[20]  Joshua D. Hartzell,et al.  Race and Mental Health Diagnosis Are Risk Factors for Highly Active Antiretroviral Therapy Failure in a Military Cohort Despite Equal Access to Care , 2007, Journal of acquired immune deficiency syndromes.

[21]  S. Kripalani,et al.  Teaching about health literacy and clear communication , 2006, Journal of General Internal Medicine.

[22]  Patrick Peretti-Watel,et al.  Drug use patterns and adherence to treatment among HIV-positive patients: evidence from a large sample of French outpatients (ANRS-EN12-VESPA 2003). , 2006, Drug and alcohol dependence.

[23]  Amar K. Das,et al.  Depression in US Hispanics: diagnostic and management considerations in family practice. , 2005, The Journal of the American Board of Family Practice.

[24]  D. Delahanty,et al.  Health-related correlates of perceived discrimination in HIV care. , 2004, AIDS patient care and STDs.

[25]  M. Ross,et al.  Psychosocial factors associated with adherence to antiretroviral medications in a sample of HIV-positive African American drug users , 2004, AIDS care.

[26]  R. Detels,et al.  Changes in adherence to highly active antiretroviral therapy medications in the Multicenter AIDS Cohort Study* , 2004, AIDS.

[27]  J. Parsons,et al.  Characteristics of HIV antiretroviral treatments, access and adherence in an ethnically diverse sample of men who have sex with men , 2003, AIDS care.

[28]  Mardge H. Cohen,et al.  Effects of depressive symptoms and mental health quality of life on use of highly active antiretroviral therapy among HIV-seropositive women. , 2002, Journal of acquired immune deficiency syndromes.

[29]  B. Yip,et al.  Intermittent use of triple-combination therapy is predictive of mortality at baseline and after 1 year of follow-up , 2002, AIDS.

[30]  R. Grant,et al.  Impact of active drug use on antiretroviral therapy adherence and viral suppression in HIV-infected drug users. , 2002 .

[31]  I. Wilson,et al.  Assessing the performance of a new depression screener for primary care (PC-SAD). , 2002, Journal of clinical epidemiology.

[32]  C. Sherbourne,et al.  Psychiatric disorders and drug use among human immunodeficiency virus-infected adults in the United States. , 2001, Archives of general psychiatry.

[33]  J. Phair,et al.  Determinants of Heterogeneous Adherence to HIV‐Antiretroviral Therapies in the Multicenter AIDS Cohort Study , 2001, Journal of acquired immune deficiency syndromes.

[34]  Seth C. Kalichman,et al.  Adherence to combination antiretroviral therapies in HIV patients of low health literacy , 1999, Journal of General Internal Medicine.

[35]  P. Kissinger,et al.  Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. , 1998, The New England journal of medicine.

[36]  Leslie E. Papke,et al.  Econometric Methods for Fractional Response Variables with an Application to 401(K) Plan Participation Rates , 1993 .

[37]  L. Derogatis,et al.  The Brief Symptom Inventory: an introductory report , 1983, Psychological Medicine.

[38]  Jacob Cohen,et al.  Applied multiple regression/correlation analysis for the behavioral sciences , 1979 .

[39]  L. Radloff.  The CES-D Scale , 1977 .

[40]  A. Beck,et al.  An inventory for measuring depression. , 1961, Archives of general psychiatry.

[41]  N. Schneiderman,et al.  MACH14: A Multi-Site Collaboration on ART Adherence Among 14 Institutions , 2012, AIDS and Behavior.

[42]  A. Anastasi.  Psychological testing, 6th ed. , 1988 .