Synthetic strategies in the construction of chromones
暂无分享,去创建一个
J. Duan | Nianguang Li | Hongyue Ma | Yu-Ping Tang | Zhi-Hao Shi | Baoquan Li | Jian-Ping Yang | Zhen-Jiang Wang | Shu-Lin Song | Jian‐Ping Yang | Shu‐Lin Song | J. Duan | Jian‐Ping Yang | Zhi‐Hao Shi
[1] K. Luthman,et al. Synthesis of 2-alkyl-substituted chromone derivatives using microwave irradiation. , 2009, The Journal of organic chemistry.
[2] T. Hansen,et al. First total synthesis of a polyunsaturated chromone metabolite isolated from the brown algae Zonaria tournefortii. , 2009, Organic letters.
[3] D. O. Bennardi,et al. Trifluoromethanesulfonic acid supported on carbon used as catalysts in the synthesis of flavones and chromones , 2009 .
[4] G. Holloway,et al. Total synthesis of the potent anticancer Aglaia metabolites (-)-silvestrol and (-)-episilvestrol and the active analogue (-)-4'-desmethoxyepisilvestrol. , 2009, Journal of the American Chemical Society.
[5] M. Ishibashi,et al. Efficient synthesis of chromone and flavonoid derivatives with diverse heterocyclic units. , 2008, Chemistry, an Asian journal.
[6] Zhong-Ning Chen,et al. Synthesis, characterization, cytotoxic activity and DNA-binding properties of the Ln(III) complexes with ethylenediiminobi(6-hydroxychromone-3-carbaldehyde) Schiff-base , 2008 .
[7] Yixiang Ding,et al. Ag(I)-catalyzed cyclization reaction of ethyl o-hydroxyphenylethynylphosphinates to phosphachromones , 2008 .
[8] J. Cornard,et al. Photochemistry of metal complexes of 3-hydroxyflavone: towards a better understanding of the influence of solar light on the metal-soil organic matter interactions , 2008, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.
[9] Seo Yun Jung,et al. Design and synthesis of 4-quinolinone 2-carboxamides as calpain inhibitors. , 2008, Bioorganic & medicinal chemistry letters.
[10] Da-qi Wang,et al. Synthesis, crystal structure and DNA-binding studies of the Ln(III) complex with 6-hydroxychromone-3-carbaldehyde benzoyl hydrazone. , 2007, Journal of inorganic biochemistry.
[11] D. O. Bennardi,et al. Supported trifluoromethanesulfonic acid as catalyst in the synthesis of flavone and chromone derivatives , 2007 .
[12] A. Pandey,et al. A chromone analog inhibits TNF-α induced expression of cell adhesion molecules on human endothelial cells via blocking NF-κB activation , 2007 .
[13] Yong Cheng,et al. A convenient synthesis of 6-demethoxycapillarisin , 2007 .
[14] Guangfu Yang,et al. Synthesis and insecticidal activity of chromanone and chromone analogues of diacylhydrazines. , 2007, Bioorganic & medicinal chemistry.
[15] J. Pezzuto,et al. Synthesis and cancer chemopreventive activity of zapotin, a natural product from Casimiroa edulis. , 2007, Journal of medicinal chemistry.
[16] Erik A. A. Wallén,et al. Synthesis of 3-aminomethyl-2-aryl- 8-bromo-6-chlorochromones. , 2007, Organic letters.
[17] M. Haratake,et al. Synthesis and characterization of styrylchromone derivatives as beta-amyloid imaging agents. , 2007, Bioorganic & medicinal chemistry.
[18] P. Langer,et al. Synthesis of 7-hydroxy-2-(2-hydroxybenzoyl)benzo[c]chromen-6-ones by sequential application of domino reactions of 1,3-bis(silyl enol ethers) with benzopyrylium triflates , 2006 .
[19] P. Langer,et al. Synthesis of 7-hydroxy-6H-benzo[c]chromen-6-ones based on a ‘[3+3] cyclization/domino retro-Michael–aldol–lactonization’ strategy , 2006 .
[20] Bao-dui Wang,et al. Synthesis, characterization, and DNA-binding properties of the Ln(III) complexes with 6-hydroxy chromone-3-carbaldehyde-(2'-hydroxy) benzoyl hydrazone. , 2006, Bioorganic & medicinal chemistry.
[21] B. Dyck,et al. Substituted chromones and quinolones as potent melanin-concentrating hormone receptor 1 antagonists. , 2006, Bioorganic & medicinal chemistry letters.
[22] M. Ishar,et al. Design, synthesis, and evaluation of novel 6-chloro-/fluorochromone derivatives as potential topoisomerase inhibitor anticancer agents. , 2006, Bioorganic & medicinal chemistry letters.
[23] R. Larock,et al. Diversity-oriented synthesis of 3-iodochromones and heteroatom analogues via ICl-induced cyclization. , 2006, The Journal of organic chemistry.
[24] G. Kabalka,et al. Microwave-assisted synthesis of functionalized flavones and chromones , 2005 .
[25] C. D. Gabbutt,et al. Synthesis of 3-alkenyl-2-arylchromones and 2,3-dialkenylchromones via acid-catalysed retro-Michael ring opening of 3-acylchroman-4-ones , 2005 .
[26] M. Son,et al. Synthesis and biological evaluation of chromone carboxamides as calpain inhibitors. , 2005, Bioorganic & medicinal chemistry letters.
[27] H. Young,et al. Synthesis and biological study of a flavone acetic acid analogue containing an azido reporting group designed as a multifunctional binding site probe. , 2005, Bioorganic & Medicinal Chemistry.
[28] J. Seijas,et al. Solvent-free synthesis of functionalized flavones under microwave irradiation. , 2005, The Journal of organic chemistry.
[29] I. Hardcastle,et al. Selective benzopyranone and pyrimido[2,1-a]isoquinolin-4-one inhibitors of DNA-dependent protein kinase: synthesis, structure-activity studies, and radiosensitization of a human tumor cell line in vitro. , 2005, Journal of medicinal chemistry.
[30] J. E. Lier,et al. Silica gel supported InBr3 and InCl3: new catalysts for the facile and rapid oxidation of 2′-hydroxychalcones and flavanones to their corresponding flavones under solvent free conditions , 2005 .
[31] I. Hardcastle,et al. Identification of a highly potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (NU7441) by screening of chromenone libraries. , 2004, Bioorganic & medicinal chemistry letters.
[32] Pablo Cironi,et al. Solid-phase synthesis of 4H-2-(3-hydroxy-4-methoxyphenyl)-naphtho[1,2-b]pyran-1-one , 2004 .
[33] L. Levine,et al. In vitro flavon-3-ol oxidation mediated by a B ring hydroxylation pattern. , 2004, Chemical research in toxicology.
[34] M. Kohno,et al. Synthesis and structure-activity relationships of thioflavone derivatives as specific inhibitors of the ERK-MAP kinase signaling pathway. , 2004, Bioorganic & medicinal chemistry.
[35] R. Hartley,et al. Potential therapeutic antioxidants that combine the radical scavenging ability of myricetin and the lipophilic chain of vitamin E to effectively inhibit microsomal lipid peroxidation. , 2004, Bioorganic & medicinal chemistry.
[36] A. Tomé,et al. [60]Fullerene–flavonoid dyads , 2004 .
[37] R. Venkateswaran,et al. Synthesis of heliannuol D, an allelochemical from Helianthus annus , 2004 .
[38] Hyun Pyo Kim,et al. Anti-inflammatory plant flavonoids and cellular action mechanisms. , 2004, Journal of pharmacological sciences.
[39] A. Singh,et al. Synthesis and characterization of triflic acid-functionalized mesoporous Zr-TMS catalysts: heterogenization of CF3SO3H over Zr-TMS and its catalytic activity , 2003 .
[40] C. Marzano,et al. Pyran derivatives. Part XXI. Antiproliferative and cytotoxic properties of novel N-substituted 4-aminocoumarins, their benzo-fused derivatives, and some related 2-aminochromones. , 2003, Farmaco.
[41] R. Venkateswaran,et al. Synthesis of O-methyl epi-heliannuol E , 2003 .
[42] V. Lokshin,et al. Reinvestigation of prototropic photochromism: 3-benzoyl-2-benzylchromones , 2003 .
[43] F. Hauser,et al. A new regiospecific preparation of xanthones. , 2003, Organic letters.
[44] A. Brossi,et al. Anti-HIV agents. Part 55: 3'R,4'R-Di-(O)-(-)-camphanoyl-2',2'-dimethyldihydropyrano[2,3-f]chromone (DCP), a novel anti-HIV agent. , 2003, Bioorganic & medicinal chemistry letters.
[45] X. Ronot,et al. Modulation of P-glycoprotein-mediated multidrug resistance by flavonoid derivatives and analogues. , 2003, Journal of medicinal chemistry.
[46] Douglas A. Horton,et al. The combinatorial synthesis of bicyclic privileged structures or privileged substructures. , 2003, Chemical reviews.
[47] G. Leoncini,et al. Coumarin, chromone, and 4(3H)-pyrimidinone novel bicyclic and tricyclic derivatives as antiplatelet agents: synthesis, biological evaluation, and comparative molecular field analysis. , 2003, Bioorganic & medicinal chemistry.
[48] P. Vázquez,et al. Mo and W heteropolyacid based catalysts applied to the preparation of flavones and substituted chromones by cyclocondensation of o-hydroxyphenyl aryl 1,3-propanediones , 2002 .
[49] M. Bordoloi,et al. An environmentally benign synthesis of aurones and flavones from 2′-acetoxychalcones using n-tetrabutylammonium tribromide , 2001 .
[50] R. Wootton,et al. Conjugate addition to 3-arylsulfinylchromones as a synthetic route to homochiral 2-substituted chromanones: Scope and limitations , 2001 .
[51] J. Borrell,et al. Solid-supported synthetic equivalents of 3-formylchromone and chromone , 2001 .
[52] A S Verkman,et al. Novel CFTR Chloride Channel Activators Identified by Screening of Combinatorial Libraries Based on Flavone and Benzoquinolizinium Lead Compounds* 210 , 2001, The Journal of Biological Chemistry.
[53] O. Chupakhin,et al. Fluoroaryl containing β,β′-dioxoesters in the synthesis of fluorobenzopyran-4(2)-ones , 2001 .
[54] S. Schenone,et al. New polycyclic pyrimidine derivatives with antiplatelet in vitro activity: synthesis and pharmacological screening. , 2001, Bioorganic & medicinal chemistry.
[55] K. Ismail,et al. Synthesis and biological evaluation of some novel 4H-benzopyran-4-one derivatives as nonsteroidal antiestrogens. , 2001, European journal of medicinal chemistry.
[56] Pradeep Kumar,et al. A novel synthesis of 4H-chromen-4-ones via intramolecular wittig reaction , 2000, Organic letters.
[57] L. D. Quin. A Guide to Organophosphorus Chemistry , 2000 .
[58] H. D. Showalter,et al. A Novel Synthesis of 2,3-Disubstituted Benzopyran-4-ones and Application to the Solid Phase , 2000 .
[59] C. Cimarelli,et al. Acylation of o-Imidoylphenol Lithium Dianions: Synthesis of 4H-Chromen-4-ylidenamines , 2000 .
[60] Rajender S. Varma,et al. Solvent‐Free Synthesis of Heterocyclic Compounds Using Microwaves , 1999 .
[61] J. Elguero,et al. Synthesis and molecular structure of 3-(2-benzyloxy-6-hydroxyphenyl)-5-styrylpyrazoles. Reaction of 2-styrylchromones and hydrazine hydrate , 1999 .
[62] G. Solladié,et al. Synthesis of (+)-(R)-5-hydroxy-6-hydroxymethyl-7-methoxy-8-methylflavanone , 1999 .
[63] Jacqueline L. Whalley,et al. The synthesis of 2-substituted isoflavones for immunoassay. , 1999, Environmental toxicology and pharmacology.
[64] R. Brueggemeier,et al. Novel synthetic routes suitable for constructing benzopyrone combinatorial libraries , 1999 .
[65] J. Casida,et al. New bioactive flavonoids and stilbenes in cubé resin insecticide , 1999 .
[66] Rajender S. Varma,et al. Solvent-free organic syntheses. using supported reagents and microwave irradiation , 1999 .
[67] J. Elguero,et al. Novel (E)‐ and (Z)‐2‐Styrylchromones from (E, E)‐2′‐Hydroxycinnamylideneacetophenones – Xanthones from Daylight Photooxidative Cyclization of (E)‐2‐Styrylchromones , 1998 .
[68] A. Petit,et al. New Solvent-Free Organic Synthesis Using Focused Microwaves , 1998 .
[69] J H Medina,et al. Detection of benzodiazepine receptor ligands in small libraries of flavone derivatives synthesized by solution phase combinatorial chemistry. , 1998, Biochemical and biophysical research communications.
[70] J. Casida,et al. Anticancer action of cubé insecticide: correlation for rotenoid constituents between inhibition of NADH:ubiquinone oxidoreductase and induced ornithine decarboxylase activities. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[71] J. F. Nixon,et al. Phosphorus: The Carbon Copy: From Organophosphorus to Phospha-organic Chemistry , 1998 .
[72] A. Lebedev,et al. Synthesis and hybridization properties of the conjugates of oligonucleotides and stabilization agents--II. , 1997, Bioorganic & medicinal chemistry.
[73] M. Mareel,et al. Anti-invasive activity of alkaloids and polyphenolics in vitro. , 1997, Bioorganic & medicinal chemistry.
[74] J. Cavaleiro,et al. Syntheses of 5‐hydroxy‐2‐(phenyl or styryl)chromones and of some halo derivatives , 1996 .
[75] J. N. Johnston,et al. Synthesis and biological evaluation of flavonoids and related compounds as gastroprotective agents , 1996 .
[76] Alan R. Katritzky,et al. Comprehensive Heterocyclic Chemistry IV , 1996 .
[77] J. Cavaleiro,et al. 5-Hydroxy-2-(phenyl or styryl) chromones: One-pot synthesis and C-6, C-8 13C NMR assignments , 1994 .
[78] J. Hoult,et al. Actions of flavonoids and coumarins on lipoxygenase and cyclooxygenase. , 1994, Methods in enzymology.
[79] D. Wishka,et al. Synthesis and biological evaluation of antiplatelet 2-aminochromones. , 1993, Journal of medicinal chemistry.
[80] F. A. Davis,et al. Enantioselective synthesis of (+)-O-trimethylsappanone B and (+)-O-trimethylbrazilin , 1993 .
[81] E. Sausville,et al. Growth inhibition with reversible cell cycle arrest of carcinoma cells by flavone L86-8275. , 1992, Journal of the National Cancer Institute.
[82] Joel Morris,et al. A novel synthesis of 2-aminochromones via phosgeniminium salts , 1992 .
[83] M. Wall. Antimutagenic agents from natural products. , 1992, Journal of natural products.
[84] T. Heffner,et al. Dopamine autoreceptor agonists as potential antipsychotics. 2. (Aminoalkoxy)-4H-1-benzopyran-4-ones. , 1991, Journal of medicinal chemistry.
[85] R. Harvey,et al. A new chromone and flavone synthesis and its utilization for the synthesis of potentially antitumorigenic polycyclic chromones and flavones , 1990 .
[86] M. Detty,et al. Synthesis of highly functionalized flavones and chromones using cycloacylation reactions and C-3 functionalization. A total synthesis of hormothamnione , 1990 .
[87] T. B. Lee,et al. Antagonists of slow reacting substance of anaphylaxis. Synthesis of a series of chromone-2-carboxylic acids. , 1977, Journal of medicinal chemistry.
[88] Y. Tohda,et al. A Convenient Synthesis of 1-Alkynyl Ketones and 2-Alkynamides , 1977 .
[89] T. B. Lee,et al. Benzodipyran derivatives with antiallergic activity. , 1976, Journal of medicinal chemistry.
[90] R. Bass. Synthesis of chromones by cyclization of 2-hydroxyphenyl ketones with boron trifluoride–diethyl ether and methanesulphonyl chloride , 1976 .
[91] H. Harnisch. Chromon‐3‐carbaldehyde , 1973 .
[92] G. P. Ellis,et al. Benzopyrones. 7. Synthesis and antiallergic activity of some 2-(5-tetrazolyl)chromones. , 1972, Journal of medicinal chemistry.
[93] J. Cox,et al. Synthesis and structure-activity relationships of disodium cromoglycate and some related compounds. , 1972, Journal of medicinal chemistry.
[94] D. Witiak,et al. 6-Chlorochroman-2-carboxylic acids. Synthesis and biological evaluation as antagonists for cholesterol biosynthesis and lipolysis in vitro. , 1971, Journal of medicinal chemistry.
[95] E. F. Ullman,et al. New photochromic cyclohexadienes , 1969 .
[96] J. Koo. Synthesis in the Chromone Series. 5,8-Dimethoxy-2-substituted Chromones and Nitrogen Analogs , 1961 .
[97] D. N. Shah,et al. Synthesis of Flavone- and Flavonol-6-carboxylic Acid and Related Derivatives , 1955 .
[98] S. Wawzonek,et al. The Preparation of 2-Methyl-6, 7-Benzochromones , 1952 .
[99] A. Sina,et al. On Visnagin and Khellin and Related Compounds. A Simple Synthesis of Chromone , 1950 .
[100] R. Adams,et al. The Formation of a Chromone by the von Pechmann Condensation of Ethyl Acetoacetate with 4-Chloro-3,5-dimethylphenol , 1944 .
[101] K. Venkataraman,et al. 124. Synthetical experiments in the chromone group. Part XIX. A synthesis of genkwanin , 1936 .
[102] K. Venkataraman,et al. 195. Synthetical experiments in the chromone group. Part XVI. Chalkones and flavanones and their oxidation to flavones by means of selenium dioxide , 1935 .
[103] R. Heywang,et al. Ueber das Chromon , 1902 .
[104] S. Ruhemann,et al. CIX.—Condensation of phenols with esters of the acetylene series. Part III. Synthesis of benzo-γ-pyrone , 1900 .