Clinical-Inspired Network for Skin Lesion Recognition

Automated skin lesion recognition methods are useful for improving the diagnostic accuracy in dermoscopy images. However, several challenges delayed the pace of the development of these methods, including limited amount of data, a lack of ability to focus on the lesion area, poor performance for distinguishing between visually-similar categories of diseases and an imbalance between different classes of training data. During practical learning and diagnosis process, doctors conduct certain strategies to tackle these challenges. Thus, it’s really appealing to involve these strategies in automated skin lesion recognition method, which could be promising for a better performance. Inspired by this, we propose a new Clinical-Inspired Network (CIN) to simulate the subjective learning and diagnostic process of doctors. To mimic the diagnostic process, we design three modules, including a lesion area attention module to crop the images, a feature extraction module to extract image features and a lesion feature attention module to focus on the important lesion parts and mine the correlation between different lesion parts. To simulate the learning process, we introduce a distinguish module. The CIN is extensively tested on ISBI2016 and 2017 challenge datasets and achieves state-of-the-art performance, which demonstrates its advantages.

[1]  Dhanesh Ramachandram,et al.  Skin Lesion Classification Using Deep Multi-scale Convolutional Neural Networks , 2017, ArXiv.

[2]  Qi Wu,et al.  Skin Lesion Classification in Dermoscopy Images Using Synergic Deep Learning , 2018, MICCAI.

[3]  H. Kittler,et al.  Diagnostic accuracy of dermoscopy. , 2002, The Lancet. Oncology.

[4]  Noel C. F. Codella,et al.  Skin lesion analysis toward melanoma detection: A challenge at the 2017 International symposium on biomedical imaging (ISBI), hosted by the international skin imaging collaboration (ISIC) , 2016, 2018 IEEE 15th International Symposium on Biomedical Imaging (ISBI 2018).

[5]  Xudong Jiang,et al.  Melanoma Recognition in Dermoscopy Images via Aggregated Deep Convolutional Features , 2019, IEEE Transactions on Biomedical Engineering.

[6]  Paul L. Rosin,et al.  Clinical Skin Lesion Diagnosis Using Representations Inspired by Dermatologist Criteria , 2018, 2018 IEEE/CVF Conference on Computer Vision and Pattern Recognition.

[7]  Thomas Brox,et al.  U-Net: Convolutional Networks for Biomedical Image Segmentation , 2015, MICCAI.

[8]  N. Dubrawsky Cancer statistics , 1989, CA: a cancer journal for clinicians.

[9]  Qi Wu,et al.  Medical image classification using synergic deep learning , 2019, Medical Image Anal..

[10]  Junji Maeda,et al.  Comparison of Segmentation Methods for Melanoma Diagnosis in Dermoscopy Images , 2009, IEEE Journal of Selected Topics in Signal Processing.

[11]  Eduardo Valle,et al.  RECOD Titans at ISIC Challenge 2017 , 2017, ArXiv.

[12]  Rahil Garnavi,et al.  Exploiting local and generic features for accurate skin lesions classification using clinical and dermoscopy imaging , 2017, 2017 IEEE 14th International Symposium on Biomedical Imaging (ISBI 2017).

[13]  S. Feldman,et al.  Incidence Estimate of Nonmelanoma Skin Cancer (Keratinocyte Carcinomas) in the U.S. Population, 2012. , 2015, JAMA dermatology.

[14]  A. Jemal,et al.  Cancer statistics, 2015 , 2015, CA: a cancer journal for clinicians.

[15]  Ghassan Hamarneh,et al.  Generalizable Feature Learning in the Presence of Data Bias and Domain Class Imbalance with Application to Skin Lesion Classification , 2019, MICCAI.

[16]  Hiroshi Koga,et al.  Image Classification of Melanoma, Nevus and Seborrheic Keratosis by Deep Neural Network Ensemble , 2017, ArXiv.

[17]  Yong Xia,et al.  Attention Residual Learning for Skin Lesion Classification , 2019, IEEE Transactions on Medical Imaging.

[18]  Hao Chen,et al.  Automated Melanoma Recognition in Dermoscopy Images via Very Deep Residual Networks , 2017, IEEE Transactions on Medical Imaging.

[19]  David Dagan Feng,et al.  Automatic Skin Lesion Analysis using Large-scale Dermoscopy Images and Deep Residual Networks , 2017, ArXiv.

[20]  Iván González-Díaz,et al.  Incorporating the Knowledge of Dermatologists to Convolutional Neural Networks for the Diagnosis of Skin Lesions , 2017, ArXiv.

[21]  M. Binder,et al.  Epiluminescence microscopy. A useful tool for the diagnosis of pigmented skin lesions for formally trained dermatologists. , 1995, Archives of dermatology.

[22]  Rahil Garnavi,et al.  Skin Disease Recognition Using Deep Saliency Features and Multimodal Learning of Dermoscopy and Clinical Images , 2017, MICCAI.

[23]  Lan Yan,et al.  A Relation Hashing Network Embedded with Prior Features for Skin Lesion Classification , 2019, MLMI@MICCAI.