Denoising MR Spectroscopic Imaging Data With Low-Rank Approximations

This paper addresses the denoising problem associated with magnetic resonance spectroscopic imaging (MRSI), where signal-to-noise ratio (SNR) has been a critical problem. A new scheme is proposed, which exploits two low-rank structures that exist in MRSI data, one due to partial separability and the other due to linear predictability. Denoising is performed by arranging the measured data in appropriate matrix forms (i.e., Casorati and Hankel) and applying low-rank approximations by singular value decomposition (SVD). The proposed method has been validated using simulated and experimental data, producing encouraging results. Specifically, the method can effectively denoise MRSI data in a wide range of SNR values while preserving spatial-spectral features. The method could prove useful for denoising MRSI data and other spatial-spectral and spatial-temporal imaging data as well.

[1]  V. Govindaraju,et al.  Proton NMR chemical shifts and coupling constants for brain metabolites , 2000, NMR in biomedicine.

[2]  Wolfgang Grodd,et al.  Parameterized evaluation of macromolecules and lipids in proton MR spectroscopy of brain diseases , 2003, Magnetic resonance in medicine.

[3]  Jürgen Gieseke,et al.  1H metabolite relaxation times at 3.0 tesla: Measurements of T1 and T2 values in normal brain and determination of regional differences in transverse relaxation , 2004, Journal of magnetic resonance imaging : JMRI.

[4]  Zhi-Pei Liang,et al.  Spatiotemporal Imaging with Partially Separable Functions , 2007, 2007 Joint Meeting of the 6th International Symposium on Noninvasive Functional Source Imaging of the Brain and Heart and the International Conference on Functional Biomedical Imaging.

[5]  Sabine Van Huffel,et al.  Exploiting Spatial Information for Estimating Metabolite Concentration in MRSI , 2009 .

[6]  Aaron Bernstein,et al.  GAVA: spectral simulation for in vivo MRS applications. , 2007, Journal of magnetic resonance.

[7]  P. Allen,et al.  In vivo NMR spectroscopy. , 1990, Basic life sciences.

[8]  James A. Cadzow,et al.  Signal enhancement-a composite property mapping algorithm , 1988, IEEE Trans. Acoust. Speech Signal Process..

[9]  Dmitriy A Yablonskiy,et al.  Natural linewidth chemical shift imaging (NL‐CSI) , 2006, Magnetic resonance in medicine.

[10]  P C Lauterbur,et al.  SLIM: Spectral localization by imaging , 1988, Magnetic resonance in medicine.

[11]  Andrew Maudsley,et al.  Improved Reconstruction for MR Spectroscopic Imaging , 2007, IEEE Transactions on Medical Imaging.

[12]  Zhi-Pei Liang,et al.  A theoretical analysis of the SLIM technique , 1993 .

[13]  Tommaso Scarabino,et al.  Proton MR spectroscopy of the brain at 3 T: an update , 2007, European Radiology.

[14]  R. Kumaresan,et al.  Estimating the parameters of exponentially damped sinusoids and pole-zero modeling in noise , 1982 .

[15]  Osama A. Ahmed,et al.  New denoising scheme for magnetic resonance spectroscopy signals , 2005, IEEE Transactions on Medical Imaging.

[16]  Justin P. Haldar,et al.  Denoising of MR spectroscopic imaging data with spatial-spectral regularization , 2010, 2010 IEEE International Symposium on Biomedical Imaging: From Nano to Macro.

[17]  Dimitri Van De Ville,et al.  BSLIM: Spectral Localization by Imaging With Explicit $B_{0}$ Field Inhomogeneity Compensation , 2007, IEEE Transactions on Medical Imaging.

[18]  Minh N. Do,et al.  Spatiotemporal denoising of MR spectroscopic imaging data by low-rank approximations , 2011, 2011 IEEE International Symposium on Biomedical Imaging: From Nano to Macro.

[20]  Justin P. Haldar,et al.  Further development in anatomically constrained MR image reconstruction: Application to multimodal imaging of mouse stroke , 2008, 2008 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[21]  Alessandro Foi,et al.  Image Denoising by Sparse 3-D Transform-Domain Collaborative Filtering , 2007, IEEE Transactions on Image Processing.

[22]  Daniel Pelletier,et al.  Evidence of elevated glutamate in multiple sclerosis using magnetic resonance spectroscopy at 3 T. , 2005, Brain : a journal of neurology.

[23]  Bart De Moor,et al.  The singular value decomposition and long and short spaces of noisy matrices , 1993, IEEE Trans. Signal Process..

[24]  Jean-Michel Morel,et al.  A Review of Image Denoising Algorithms, with a New One , 2005, Multiscale Model. Simul..

[25]  Mathews Jacob,et al.  Reduction of distortions in MRSI using a new signal model , 2009, 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro.

[26]  Sanjay Kalra,et al.  T2 measurement and quantification of glutamate in human brain in vivo , 2006, Magnetic resonance in medicine.

[27]  Juan V. Lorenzo-Ginori,et al.  Signal de-noising in magnetic resonance spectroscopy using wavelet transforms , 2002 .

[28]  V. Marčenko,et al.  DISTRIBUTION OF EIGENVALUES FOR SOME SETS OF RANDOM MATRICES , 1967 .

[29]  Zhi-Pei Liang,et al.  Correction of field inhomogeneity effects on limited k-space MRSI data using anatomical constraints , 2010, 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology.

[30]  H. Andrews,et al.  Singular value decompositions and digital image processing , 1976 .

[31]  Zhi-Pei Liang,et al.  Anatomically constrained reconstruction from noisy data , 2008, Magnetic resonance in medicine.

[32]  Shi-Jiang Li,et al.  Differentiation of metabolic concentrations between gray matter and white matter of human brain by in vivo 1H magnetic resonance spectroscopy , 1998, Magnetic resonance in medicine.

[33]  Zhi-Pei Liang,et al.  SPATIOTEMPORAL IMAGINGWITH PARTIALLY SEPARABLE FUNCTIONS , 2007, 2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro.

[34]  D. van Ormondt,et al.  SVD-based quantification of magnetic resonance signals , 1992 .

[35]  P. Toint,et al.  Conditioning of infinite Hankel matrices of finite rank , 2000 .

[36]  André Briguet,et al.  Improvements of quantitation by using the Cadzow enhancement procedure prior to any linear-prediction methods , 1994 .

[37]  R. Shibata Selection of the order of an autoregressive model by Akaike's information criterion , 1976 .

[38]  John Kornak Bayesian reconstruction of low resolution magnetic resonance imaging modalities , .

[39]  P. Barker,et al.  In vivo proton MR spectroscopy of the human brain , 2006 .