Cardio Vascular Grafts: Existing Problems and Proposed Solutions

The cardiovascular diseases are becoming a major fear in the present era all over the globe. The cardiovascular tissue engineering (TE) can become an ideal substitute to replace all of this cardiac problems like: cardiovascular grafting, valves, microvessel construction, aorta and vein formation by using of some regularly used textile fibers like: ePTFE, PGA, nylon, PET (Dacron), polygalactin etc. this artificial health devices are fully bio-compatible, bio-degradable within the human body and also FDA approved. In this current review paper the existing problems related to the different cardiovascular grafts, their flow mechanics inside the human body, microvessel building engineering and their ideal examples has been extensively discussed.

[1]  R. Guidoin,et al.  In vitro exposure of a novel polyesterurethane graft to enzymes: a study of the biostability of the Vascugraft arterial prosthesis. , 1994, Biomaterials.

[2]  F. Mohr,et al.  Sutureless mitral valve replacement with bioprostheses and Nitinol attachment rings: feasibility in acute pig experiments. , 2011, The Journal of thoracic and cardiovascular surgery.

[3]  Todd N. McAllister,et al.  Tissue engineering by self-assembly , 2011 .

[4]  Jeffrey M. Caves,et al.  The use of microfiber composites of elastin-like protein matrix reinforced with synthetic collagen in the design of vascular grafts. , 2010, Biomaterials.

[5]  Sangwon Chung,et al.  Bioresorbable elastomeric vascular tissue engineering scaffolds via melt spinning and electrospinning. , 2010, Acta biomaterialia.

[6]  Freddy Yin Chiang Boey,et al.  Implanted cardiovascular polymers: Natural, synthetic and bio-inspired , 2008 .

[7]  Monica T Hinds,et al.  Mechanical property characterization of electrospun recombinant human tropoelastin for vascular graft biomaterials. , 2012, Acta biomaterialia.

[8]  V. Riambau,et al.  Early abdominal aortic endografts: a decade follow-up results. , 2010, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

[9]  B. Conklin,et al.  Development and evaluation of a novel decellularized vascular xenograft. , 2002, Medical engineering & physics.

[10]  D. Bezuidenhout,et al.  A computational study of knitted Nitinol meshes for their prospective use as external vein reinforcement. , 2008, Journal of biomechanics.

[11]  D. Mantovani,et al.  Improving arterial prosthesis neo-endothelialization: application of a proactive VEGF construct onto PTFE surfaces. , 2005, Biomaterials.

[12]  Alexander M Seifalian,et al.  The roles of tissue engineering and vascularisation in the development of micro-vascular networks: a review. , 2005, Biomaterials.

[13]  R. Guidoin,et al.  In vivo evaluation of hydrophobic and fibrillar microporous polyetherurethane urea graft. , 1989, Biomaterials.

[14]  B. Kozlowski,et al.  Long-term dilatation of polyester and expanded polytetrafluoroethylene tube grafts after open repair of infrarenal abdominal aortic aneurysms. , 2011, Journal of vascular surgery.

[15]  A. Seifalian,et al.  Optimal endothelialisation of a new compliant poly(carbonate-urea)urethane vascular graft with effect of physiological shear stress. , 2000, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

[16]  W. Sikorska,et al.  Novel block copolymers of atactic PHB with natural PHA for cardiovascular engineering: Synthesis and characterization , 2012 .

[17]  G. Engelmayr,et al.  Finite element analysis of an accordion-like honeycomb scaffold for cardiac tissue engineering. , 2010, Journal of biomechanics.

[18]  D. Bezuidenhout,et al.  Prosthetic vascular grafts: wrong models, wrong questions and no healing. , 2007, Biomaterials.

[19]  Oliver Germershaus,et al.  Electrospun matrices for localized drug delivery: current technologies and selected biomedical applications. , 2012, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[20]  Gerhard Sommer,et al.  3D constitutive modeling of the biaxial mechanical response of intact and layer-dissected human carotid arteries. , 2012, Journal of the mechanical behavior of biomedical materials.

[21]  Julie H. Campbell,et al.  Advances in vascular tissue engineering. , 2003, Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.

[22]  N. Chakfé,et al.  In vitro approach to the dilative behavior of knitted vascular prosthetic grafts. , 2008, Annals of vascular surgery.

[23]  Terry J. Smith,et al.  Human coronary artery smooth muscle cell response to a novel PLA textile/fibrin gel composite scaffold. , 2008, Acta biomaterialia.

[24]  Ville Ellä,et al.  Fibrin-polylactide-based tissue-engineered vascular graft in the arterial circulation. , 2010, Biomaterials.

[25]  Steven G Wise,et al.  A multilayered synthetic human elastin/polycaprolactone hybrid vascular graft with tailored mechanical properties. , 2011, Acta biomaterialia.

[26]  S. Haulon,et al.  Safety, healing, and efficacy of vascular prostheses coated with hydroxypropyl-β-cyclodextrin polymer: experimental in vitro and animal studies. , 2012, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

[27]  R. Guidoin,et al.  Biocompatibility of the Vascugraft: evaluation of a novel polyester urethane vascular substitute by an organotypic culture technique. , 1992, Biomaterials.

[28]  Thomas Franz,et al.  A constitutive model for the warp-weft coupled non-linear behavior of knitted biomedical textiles. , 2010, Biomaterials.

[29]  Alexander M Seifalian,et al.  The use of animal models in developing the discipline of cardiovascular tissue engineering: a review. , 2004, Biomaterials.

[30]  Holger Zernetsch,et al.  Electrospun cellular microenvironments: Understanding controlled release and scaffold structure. , 2011, Advanced drug delivery reviews.