IL-6 expression induced by adenosine A2b receptor stimulation in U373 MG cells depends on p38 mitogen activated kinase and protein kinase C
暂无分享,去创建一个
B. Fiebich | C. Schmidt | R. Akundi | K. Biber | D. Calker | R. Butcher | Maike Hamke | F. Willmroth
[1] M. Hüll,et al. Serotonin via 5‐HT7 receptors activates p38 mitogen‐activated protein kinase and protein kinase C ɛ resulting in interleukin‐6 synthesis in human U373 MG astrocytoma cells , 2005, Journal of neurochemistry.
[2] M. Hüll,et al. 1‐trichloromethyl‐1,2,3,4‐tetrahydro‐β‐carboline‐induced apoptosis in the human neuroblastoma cell line SK‐N‐SH , 2004, Journal of neurochemistry.
[3] Wan-Wan Lin,et al. PKA-dependent activation of PKC, p38 MAPK and IKK in macrophage: implication in the induction of inducible nitric oxide synthase and interleukin-6 by dibutyryl cAMP. , 2004, Cellular signalling.
[4] C. Lang,et al. Epinephrine stimulates IL-6 expression in skeletal muscle and C2C12 myoblasts: role of c-Jun NH2-terminal kinase and histone deacetylase activity. , 2004, American journal of physiology. Endocrinology and metabolism.
[5] B. Cronstein,et al. Adenosine: an endogenous regulator of innate immunity. , 2004, Trends in immunology.
[6] C. Szabó,et al. ADENOSINE STIMULATES CREB ACTIVATION IN MACROPHAGES VIA A P38 MAPK‐MEDIATED MECHANISM: 165 , 2003 .
[7] M. Merola,et al. p38 MAPK is a critical regulator of the constitutive and the β4 integrin‐regulated expression of IL‐6 in human normal thymic epithelial cells , 2003, European journal of immunology.
[8] B. Fredholm,et al. The G(s)-coupled adenosine A(2B) receptor recruits divergent pathways to regulate ERK1/2 and p38. , 2003, Experimental cell research.
[9] Edwin A. Deitch,et al. cDNA Microarray Analysis Reveals a Nuclear Factor-κB-Independent Regulation of Macrophage Function by Adenosine , 2003, Journal of Pharmacology and Experimental Therapeutics.
[10] J. Elias,et al. Adenosine mediates IL-13-induced inflammation and remodeling in the lung and interacts in an IL-13-adenosine amplification pathway. , 2003, The Journal of clinical investigation.
[11] B. Fredholm,et al. Adenosine A2B receptors modulate cAMP levels and induce CREB but not ERK1/2 and p38 phosphorylation in rat skeletal muscle cells , 2003 .
[12] B. Fiebich,et al. Valproic acid inhibits substance P‐induced activation of protein kinase C epsilon and expression of the substance P receptor , 2003, Journal of neurochemistry.
[13] G. Wenk,et al. The influence of brain inflammation upon neuronal adenosine A2B receptors , 2003, Journal of neurochemistry.
[14] J. Schrader,et al. Defining the Involvement of p38α MAPK in the Production of Anti- and Proinflammatory Cytokines Using an SB 203580-resistant Form of the Kinase* , 2003, Journal of Biological Chemistry.
[15] M. Scanlon,et al. Adenosine‐induced IL‐6 expression in pituitary folliculostellate cells is mediated via A2b adenosine receptors coupled to PKC and p38 MAPK , 2003, British journal of pharmacology.
[16] Kazuhide Inoue. Microglial activation by purines and pyrimidines , 2002, Glia.
[17] P. Hasselgren,et al. Multiple transcription factors regulating the IL-6 gene are activated by cAMP in cultured Caco-2 cells. , 2002, American journal of physiology. Regulatory, integrative and comparative physiology.
[18] T. Nakao,et al. Role of mitogen‐activated protein kinase family in serum‐induced leukaemia inhibitory factor and interleukin‐6 secretion by bone marrow stromal cells , 2002, British journal of pharmacology.
[19] M. Schwaninger,et al. Interleukin-6 (IL-6): A Possible Neuromodulator Induced by Neuronal Activity , 2002, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.
[20] M. Hastings,et al. Rhythmic gene expression in pituitary depends on heterologous sensitization by the neurohormone melatonin , 2002, Nature Neuroscience.
[21] B. Fredholm,et al. International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors. , 2001, Pharmacological reviews.
[22] David W. Anderson,et al. SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[23] M. Hüll,et al. Mechanisms of prostaglandin E2‐induced interleukin‐6 release in astrocytes: possible involvement of EP4‐like receptors, p38 mitogen‐activated protein kinase and protein kinase C , 2001, Journal of neurochemistry.
[24] J. Gutkind,et al. G-protein-coupled receptors and signaling networks: emerging paradigms. , 2001, Trends in pharmacological sciences.
[25] M. Poo,et al. Binding of DCC by Netrin-1 to Mediate Axon Guidance Independent of Adenosine A2B Receptor Activation , 2001, Science.
[26] H. Chae,et al. Blockade of p38 mitogen-activated protein kinase pathway inhibits interleukin-6 release and expression in primary neonatal cardiomyocytes. , 2001, Research communications in molecular pathology and pharmacology.
[27] H. Boddeke,et al. Interleukin-6 Enhances Expression of Adenosine A1 Receptor mRNA and Signaling in Cultured Rat Cortical Astrocytes and Brain Slices , 2001, Neuropsychopharmacology.
[28] G. Chrousos,et al. The sympathetic nerve--an integrative interface between two supersystems: the brain and the immune system. , 2000, Pharmacological reviews.
[29] The Neuropeptide Substance P Activates p38 Mitogen-Activated Protein Kinase Resulting in IL-6 Expression Independently from NF-κB1 , 2000, The Journal of Immunology.
[30] W. V. Berghe,et al. Signal transduction by tumor necrosis factor and gene regulation of the inflammatory cytokine interleukin-6. , 2000, Biochemical pharmacology.
[31] A. Chédotal,et al. Netrin-1-mediated axon outgrowth and cAMP production requires interaction with adenosine A2b receptor , 2000, Nature.
[32] P. Cohen,et al. Specificity and mechanism of action of some commonly used protein kinase inhibitors , 2000 .
[33] K. Klotz,et al. Signaling by extracellular nucleotides and nucleosides , 2000, Naunyn-Schmiedeberg's Archives of Pharmacology.
[34] Alexandre de Mendonça,et al. Adenosine: does it have a neuroprotective role after all? , 2000, Brain Research Reviews.
[35] B. Fredholm,et al. Human adenosine A(1), A(2A), A(2B), and A(3) receptors expressed in Chinese hamster ovary cells all mediate the phosphorylation of extracellular-regulated kinase 1/2. , 2000, Molecular pharmacology.
[36] Wyeth Wasserman,et al. Structure and function of adenosine receptors and their genes , 2000, Naunyn-Schmiedeberg's Archives of Pharmacology.
[37] M. Schwaninger,et al. Adenosine‐induced expression of interleukin‐6 in astrocytes through protein kinase A and NF‐IL‐6 , 2000, Glia.
[38] G. King,et al. Identification of PKC-isoform-specific biological actions using pharmacological approaches. , 2000, Trends in pharmacological sciences.
[39] E. Benveniste,et al. Interleukin-6 expression and regulation in astrocytes , 1999, Journal of Neuroimmunology.
[40] G. Haegeman,et al. The Nuclear Factor-κB Engages CBP/p300 and Histone Acetyltransferase Activity for Transcriptional Activation of the Interleukin-6 Gene Promoter* , 1999, The Journal of Biological Chemistry.
[41] C. Manthey,et al. Cytokine mRNA decay is accelerated by an inhibitor of p38-mitogen-activated protein kinase , 1999, Inflammation Research.
[42] J. Linden,et al. Characterization of human A(2B) adenosine receptors: radioligand binding, western blotting, and coupling to G(q) in human embryonic kidney 293 cells and HMC-1 mast cells. , 1999, Molecular pharmacology.
[43] I. Biaggioni,et al. Role of p38 mitogen-activated protein kinase and extracellular signal-regulated protein kinase kinase in adenosine A2B receptor-mediated interleukin-8 production in human mast cells. , 1999, Molecular pharmacology.
[44] B. Fiebich,et al. Carbamazepine-Induced Upregulation of Adenosine A1-Receptors in Astrocyte Cultures Affects Coupling to the Phosphoinositol Signaling Pathway , 1999, Neuropsychopharmacology.
[45] K. Miyazawa,et al. Regulation of Interleukin-1β-induced Interleukin-6 Gene Expression in Human Fibroblast-like Synoviocytes by p38 Mitogen-activated Protein Kinase* , 1998, The Journal of Biological Chemistry.
[46] H. Przuntek,et al. Short communication Interleukin‐6 levels in cerebrospinal fluid inversely correlate to severity of Parkinson's disease , 1998, Acta neurologica Scandinavica.
[47] J. Bauer,et al. Substance P and Histamine Induce Interleukin‐6 Expression in Human Astrocytoma Cells by a Mechanism Involving Protein Kinase C and Nuclear Factor‐IL‐6 , 1998, Journal of neurochemistry.
[48] N. Rothwell,et al. Cerebral Interleukin-6 is Neuroprotective during Permanent Focal Cerebral Ischemia in the Rat , 1998, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[49] I Biaggioni,et al. Adenosine A2B receptors. , 1997, Pharmacological reviews.
[50] S. Rose-John,et al. Activation of gp 130 by IL‐6/soluble IL‐6 receptor induces neuronal differentiation , 1997, The European journal of neuroscience.
[51] M. Mirabet,et al. Calcium mobilization in Jurkat cells via A2b adenosine receptors , 1997, British journal of pharmacology.
[52] S. Ferroni,et al. Protective Mechanisms of Adenosine in Neurons and Glial Cells a , 1997, Annals of the New York Academy of Sciences.
[53] Markus Schwaninger,et al. Stimulation of Interleukin‐6 Secretion and Gene Transcription in Primary Astrocytes by Adenosine , 1997, Journal of neurochemistry.
[54] U. Otten,et al. Interleukin-6 (IL-6)—A molecule with both beneficial and destructive potentials , 1997, Progress in Neurobiology.
[55] Knut Biber,et al. Adenosine A1 Receptor-Mediated Activation of Phospholipase C in Cultured Astrocytes Depends on the Level of Receptor Expression , 1997, The Journal of Neuroscience.
[56] Y. Nomura,et al. Protein kinase A-dependent IL-6 production induced by calcitonin in human glioblastoma A172 cells , 1997, Journal of Neuroimmunology.
[57] C. Heyser,et al. Progressive decline in avoidance learning paralleled by inflammatory neurodegeneration in transgenic mice expressing interleukin 6 in the brain. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[58] M. Hüll,et al. Prostaglandin E2 Induces Interleukin‐6 Synthesis in Human Astrocytoma Cells , 1997, Journal of neurochemistry.
[59] M. Gschwendt,et al. Inhibition of protein kinase C μ by various inhibitors. Inhibition from protein kinase c isoenzymes , 1996 .
[60] H. Kiyama,et al. Accelerated Nerve Regeneration in Mice by upregulated expression of interleukin (IL) 6 and IL-6 receptor after trauma , 1996, The Journal of experimental medicine.
[61] J. Bauer,et al. Interleukin‐1β Uses Common and Distinct Signaling Pathways for Induction of the Interleukin‐6 and Tumor Necrosis Factor α Genes in the Human Astrocytoma Cell Line U373 , 1996 .
[62] J. Bauer,et al. Adenosine A2b Receptors Mediate an Increase in Interleukin (IL)‐6 mRNA and IL‐6 Protein Synthesis in Human Astroglioma Cells , 1996, Journal of neurochemistry.
[63] J. Westwick,et al. Interleukin-1-induced IL-8 and IL-6 gene expression and production in human mesangial cells is differentially regulated by cAMP. , 1995, Kidney international.
[64] P. Musiani,et al. IL‐6 Expression in Neurons of Transgenic Mice Causes Reactive Astrocytosis and Increase in Ramified Microglial Cells but no Neuronal Damage , 1995, The European journal of neuroscience.
[65] F. Urbani,et al. Interleukin-6 production by U373 MG, a human astrocytoma cell line: different pathways involved in substance P and lipopolysaccharide activation , 1995, Journal of Neuroimmunology.
[66] E. Cadman,et al. cAMP is not involved in interleukin-1-induced interleukin-6 release from human astrocytoma cells , 1994, Neuroscience Letters.
[67] E. Cadman,et al. Regulation of the Release of Interleukin‐6 from Human Astrocytoma Cells , 1994, Journal of neurochemistry.
[68] B. Fredholm,et al. Adenosine A2B receptor signalling is altered by stimulation of bradykinin or interleukin receptors in astroglioma cells , 1994, Neurochemistry International.
[69] J. Murray,et al. Positive modulation of intracellular Ca2+ levels by adenosine A2b receptors, prostacyclin, and prostaglandin E1 via a cholera toxin-sensitive mechanism in human erythroleukemia cells. , 1994, Molecular pharmacology.
[70] F. Marks,et al. Rottlerin, a novel protein kinase inhibitor. , 1994, Biochemical and biophysical research communications.
[71] J. Gauldie,et al. The acute phase response. , 1994, Immunology today.
[72] B. Rabin,et al. Serum interleukin-6 concentration in schizophrenia: Elevation associated with duration of illness , 1994, Psychiatry Research.
[73] P. Parker,et al. Isoenzyme specificity of bisindolylmaleimides, selective inhibitors of protein kinase C. , 1993, The Biochemical journal.
[74] G. Martiny-Baron,et al. Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976. , 1993, The Journal of biological chemistry.
[75] H. Hug,et al. Protein kinase C isoenzymes: divergence in signal transduction? , 1993, The Biochemical journal.
[76] M. W. Flye,et al. Prostaglandin E2 downregulates Kupffer cell production of IL-1 and IL-6 during hepatic regeneration. , 1993, The American journal of physiology.
[77] T. Abrams,et al. cAMP modulates multiple K+ currents, increasing spike duration and excitability in Aplysia sensory neurons. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[78] J. Bauer,et al. Detection of interleukin-6 and alpha 2-macroglobulin immunoreactivity in cortex and hippocampus of Alzheimer's disease patients. , 1992, Laboratory investigation; a journal of technical methods and pathology.
[79] J. Bauer,et al. The participation of interleukin-6 in the pathogenesis of Alzheimer's disease. , 1992 .
[80] K. Albermann,et al. Nuclear Factor Kb: An Oxidative Stress-Responsive Transcription Factor of Eukaryotic Cells (A Review) , 1992 .
[81] H. Coste,et al. The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. , 1991, The Journal of biological chemistry.
[82] H. Yagisawa,et al. IL1 induces proliferation and IL6 mRNA expression in a human astrocytoma cell line: positive and negative modulation by chorela toxin and cAMP. , 1990, Biochemical and biophysical research communications.
[83] J. Vilček,et al. Synthesis of interleukin 6 (interferon-beta 2/B cell stimulatory factor 2) in human fibroblasts is triggered by an increase in intracellular cyclic AMP. , 1988, The Journal of biological chemistry.
[84] T. Taniguchi,et al. Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin , 1986, Nature.
[85] Margarete Müller,et al. ADENOSINE REGULATES VIA TWO DIFFERENT TYPES OF RECEPTORS, THE ACCUMULATION OF CYCLIC AMP IN CULTURED BRAIN CELLS , 1979, Journal of neurochemistry.
[86] Margarete Müller,et al. Adenosine inhibits the accumulation of cyclic AMP in cultured brain cells , 1978, Nature.
[87] U. K. Laemmli,et al. Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4 , 1970, Nature.