Occurrence of ochratoxin A in domestic beers and wines from Tunisia by immunoaffinity clean-up and liquid chromatography

A survey on the occurrence of ochratoxin A (OTA) in wines and beers produced in Tunisia was carried out. Wines and beers were analysed using immunoaffinity column clean-up and high-performance liquid chromatography coupled to a fluorometric detector. OTA was detected in 29 wine samples, with an incidence of contamination of 85%. The OTA levels ranged between 0.09 and 1.5 µg/L. Neither of the studied samples showed levels above the European regulatory limit (2 µg/L). OTA was detected in 17 beer samples with an incidence of contamination of 45%. The OTA levels ranged between 0.04 and 0.35 µg/L. The OTA dietary intake by the consumption of wine and beer may be considered as negligible. The obtained results showed high incidence of OTA in Tunisian wines and beers; however, there are no toxicological risks for Tunisian consumers through their consumption of such processed products using cereals and grapes.

[1]  S. Rastelli,et al.  Mycotoxin occurrence in beer produced in several European countries , 2011 .

[2]  Angel Medina,et al.  An overview of ochratoxin A in beer and wine. , 2007, International journal of food microbiology.

[3]  C. V. Van Peteghem,et al.  Intake of ochratoxin A and deoxynivalenol through beer consumption in Belgium , 2007, Food additives and contaminants.

[4]  V. Sanchis,et al.  Occurrence of ochratoxigenic fungi and ochratoxin A in grapes from a Tunisian vineyard. , 2007, International journal of food microbiology.

[5]  N. Magan,et al.  European research on ochratoxin A in grapes and wine. , 2006, International journal of food microbiology.

[6]  J. Pitt,et al.  Australian research on ochratoxigenic fungi and ochratoxin A. , 2006, International journal of food microbiology.

[7]  F. Mateo,et al.  New method for determination of ochratoxin A in beer using zinc acetate and solid-phase extraction silica cartridges. , 2006, Journal of chromatography. A.

[8]  E. González-Peñas,et al.  Study on ochratoxin A in cereal-derived products from Spain , 2005 .

[9]  M. Jiménez,et al.  Determination of ochratoxin A in beer marketed in Spain by liquid chromatography with fluorescence detection using lead hydroxyacetate as a clean-up agent. , 2005, Journal of chromatography. A.

[10]  C. Brera,et al.  Exposure assessment to ochratoxin A from the consumption of Italian and Hungarian wines , 2005 .

[11]  K. Jørgensen Occurrence of ochratoxin A in commodities and processed food--a review of EU occurrence data. , 2005, Food additives and contaminants.

[12]  J. M. Soriano,et al.  Concentration of ochratoxin A in wines from supermarkets and stores of Valencian Community (Spain). , 2004, Journal of chromatography. A.

[13]  R. Schothorst,et al.  Report from SCOOP task 3.2.10 "collection of occurrence data of Fusarium toxins in food and assessment of dietary intake by the population of EU member states". Subtask: trichothecenes. , 2004, Toxicology letters.

[14]  M. Arıcı,et al.  A Survey of Barley, Malt and Beer Contamination with Ochratoxin A in Turkey , 2004 .

[15]  S. Abid,et al.  Ochratoxin a and human chronic nephropathy in Tunisia: is the situation endemic? , 2003, Human & experimental toxicology.

[16]  A. Pietri,et al.  Occurrence of ochratoxin A in Italian wines , 2001, Food additives and contaminants.

[17]  A. Benayada,et al.  Ochratoxin A in beverages from Morocco: a preliminary survey , 2001, Food additives and contaminants.

[18]  H Otteneder,et al.  Occurrence of ochratoxin A (OTA) in wines: influence of the type of wine and its geographical origin , 2000, Food additives and contaminants.

[19]  A. Visconti,et al.  Determination of ochratoxin A in domestic and imported beers in italy by immunoaffinity clean-up and liquid chromatography. , 2000, Journal of chromatography. A.

[20]  K. Jørgensen Survey of pork, poultry, coffee, beer and pulses for ochratoxin A. , 1998, Food additives and contaminants.

[21]  E. Creppy,et al.  Human ochratoxicosis and nephropathy in Egypt: A preliminary study , 1998, Human & experimental toxicology.

[22]  B. Zimmerli,et al.  Ochratoxin A in table wine and grape-juice: occurrence and risk assessment. , 1996, Food additives and contaminants.

[23]  H. Bacha,et al.  Human Nephropathy Related to Ochratoxin a in Tunisia , 1996 .

[24]  M. Castegnaro,et al.  Molecular and epidemiological approaches to the etiology of urinary tract tumors in an area with Balkan endemic nephropathy. , 1996, Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer.

[25]  P. Krogh Role of ochratoxin in disease causation. , 1992, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[26]  F. Jonsyn-Ellis Ochratoxin a: Any Cause for Concern in Sub Saharan Africa? , 2012 .

[27]  P. Krogh Casual associations of mycotoxic nephropathy. , 1978, Acta pathologica et microbiologica Scandinavica. Supplement.