Measurement of Intermolecular Interactions of Hydroxamic Acids in DMSO

Apparent molar volumes of two hydroxamic acids, N-o-tolyl-4-methylbenzoand N-p-tolyl-2methylbenzohave been calculated from experimental data of densities (ρ) in dimethyl sulfoxide at various temperatures (298.15 to 318.15 K). Results obtained have been discussed in terms of intermolecular interactions and a comprehensive discussion has been provided. The apparent molar volumes at infinite dilution and the slopes of Masson’s equation are computed to interpret the solute-solvent interactions. The expansibility is also calculated. Structure breaking capacities of these molecules have been inferred from the sign of [∂V 0 φ / ∂T] P, Both the compounds behave as structure breakers in DMSO.

[1]  S. P. Ijardar,et al.  Studies of Partial Molar Volumes of Alkylamines in Non-electrolyte Solvents. IV. Alkyl Amines in Cyclic Ethers at 303.15 K , 2009 .

[2]  M. Ozdemir,et al.  Apparent molar volume and apparent molar isentropic compressibility of glycerol in fructose-water at different temperatures , 2008 .

[3]  Mahamad Hakimi Ibrahim,et al.  Densities and viscosities of aqueous solutions of 1-propanol and 2-propanol at temperatures from 293.15 K to 333.15 K , 2007 .

[4]  M. S. Baymak,et al.  Solvent–solute interactions of isomeric phthalaldehydes in aqueous solutions , 2007 .

[5]  M. Iqbal,et al.  Partial molar volume of paracetamol in water, 0.1 M HCl and 0.154 M NaCl at T = (298.15, 303.15, 308.15 and 310.65) K and at 101.325 kPa , 2005 .

[6]  H. Iloukhani,et al.  Excess molar enthalpies of methyl isobutyl ketone (MIBK) with alkan-1-ols (C1–C6) and their correlations at 298.15 K , 2005 .

[7]  H. Iloukhani,et al.  Excess molar enthalpies of formamide + some alkan-1-ols (C1–C6) and their correlations at 298.15 K , 2003 .

[8]  H. Zarei,et al.  Excess Molar Enthalpies of N,N-Dimethylformamide + Alkan-1-ols (C1−C6) at 298.15 K , 2002 .

[9]  S. Akhtar,et al.  Excess Molar Volumes and Thermal Expansivities of Aqueous Solutions of Dimethylsulfoxide, Tetrahydrofuran and 1,4-Dioxane , 2002 .

[10]  R. Pande,et al.  Apparent Molar Volumes and Refractive Indices of Hydroxamic Acid Solutions , 2002 .

[11]  S. Hanessian,et al.  Synthesis of Hydroxamic Esters via Alkoxyaminocarbonylation of β-Dicarbonyl Compounds. , 1999 .

[12]  A. Gearing,et al.  Design and therapeutic application of matrix metalloproteinase inhibitors. , 1999, Chemical reviews.

[13]  S. Hanessian,et al.  Synthesis of Hydroxamic Esters via Alkoxyaminocarbonylation of β-Dicarbonyl Compounds , 1999 .

[14]  C. Brooks,et al.  Asymmetric synthesis of (R)-N-3-butyn-2-yl-N-hydroxyurea, a key intermediate for 5-lipoxygenase inhibitors , 1996 .

[15]  S. Schulz,et al.  Excess molar enthalpies of acetone + water, cyclohexane, methanol, 1-propanol, 2-propanol, 1-butanol and 1-pentanol at 283.15, 298.15, 323.15, 343.15 and 363.15 K , 1995 .

[16]  D. Sands,et al.  Viscosities, Densities, and Related Properties of Solutions of Some Sugars in Dimethyl Sulfoxide. , 1964 .