Total Parenteral Nutrition Preparation for a Known Latex-Allergic Patient

This article describes how a hospital pharmacy department provided total parenteral nutrition (TPN) fora known latex-allergic patient to safely meet the patient's nutritional needs and maintain proper aseptic technique during the compounding process. After numerous attempts to feed the patient enterally failed, total parenteral nutrition was recommended. It was decided that preparation and administration of parenteral nutrition for this patient should follow the recently initiated Pharmacy policy for the preparation of sterile products for latex-allergic patients as closely as possible. After reviewing the compounding process, it was determined that a base solution of protein and dextrose could be safely prepared by making sure that the products we used did not contain latex and that the process did not involve puncturing of latex-containing ports or stoppers. All other ingredients would be added manually. Prior to discharge, enteral feeding was reintroduced and the TPN solution was discontinued.

[1]  T. Burke,et al.  Lack of latex allergen contamination of solutions withdrawn from vials with natural rubber stoppers. , 2000, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.

[2]  R. T. Bowyer Latex allergy: how to identify it and the people at risk. , 1999, Journal of clinical nursing.

[3]  C. Walsh-Kelly,et al.  Latex allergy: a patient and health care system emergency. , 1998, Annals of emergency medicine.

[4]  P. Kellett Latex allergy: a review. , 1997, Journal of emergency nursing: JEN : official publication of the Emergency Department Nurses Association.

[5]  D. Beezhold,et al.  Allergy to Latex Rubber , 1995, Annals of Internal Medicine.

[6]  V. Kurup,et al.  The diagnosis of natural rubber latex allergy. , 1994, The Journal of allergy and clinical immunology.

[7]  E. Canizares Annual Pharmaceutical Manufacturers Directory—2000 , 1995, Hospital Pharmacy.

[8]  C. Hamann Natural Rubber Latex Protein Sensitivity in Review , 1993 .

[9]  G. D. Dunn,et al.  Essential Fatty Acid Deficiency During Total Parenteral Nutrition , 1981, Annals of surgery.

[10]  W. Eaglstein,et al.  Human essential fatty acid deficiency: treatment by topical application of linoleic acid. , 1977, Archives of dermatology.