Activity and structural dynamics of human ABCA1 in a lipid membrane.
暂无分享,去创建一个
M. Liao | C. L. Morales-Pérez | Alan T. Culbertson | Ashlee M. Plummer-Medeiros | A. M. Plummer-Medeiros
[1] E. Tajkhorshid,et al. Cryo‐EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms , 2022, The EMBO journal.
[2] W. S. Davidson,et al. ABCA1 is an extracellular phospholipid translocase , 2022, Nature Communications.
[3] Xiaochun Li,et al. Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states , 2022, Nature Cardiovascular Research.
[4] L. Molday,et al. Structure and function of ABCA4 and its role in the visual cycle and Stargardt macular degeneration , 2021, Progress in Retinal and Eye Research.
[5] F. van Petegem,et al. Cryo-EM structures of the ABCA4 importer reveal mechanisms underlying substrate binding and Stargardt disease , 2021, Nature Communications.
[6] S. S.,et al. Elucidating the Structural Features of ABCA1 in its Heterogeneous Membrane Environment , 2021, bioRxiv.
[7] M. Liao,et al. Mechanism of LolCDE as a molecular extruder of bacterial triacylated lipoproteins , 2021, Nature Communications.
[8] X. Gong,et al. Structural basis of substrate recognition and translocation by human ABCA4 , 2021, Nature Communications.
[9] Jue Chen,et al. Molecular structures of the eukaryotic retinal importer ABCA4 , 2021, eLife.
[10] M. Liao,et al. The ABCs of Sterol Transport. , 2020, Annual review of physiology.
[11] M. Liao,et al. ABCG2 transports anticancer drugs via a closed-to-open switch , 2020, Nature Communications.
[12] J. Smeitink,et al. Brothers in Arms: ABCA1- and ABCG1-Mediated Cholesterol Efflux as Promising Targets in Cardiovascular Disease Treatment , 2019, Pharmacological Reviews.
[13] M. Simon,et al. Even Cancer Cells Watch Their Cholesterol! , 2019, Molecular cell.
[14] R. Gaudet,et al. Mechanics and pharmacology of substrate selection and transport by eukaryotic ABC exporters , 2019, Nature Structural & Molecular Biology.
[15] K. Beis,et al. Learning the ABCs one at a time: structure and mechanism of ABC transporters. , 2019, Biochemical Society transactions.
[16] Erik Lindahl,et al. New tools for automated high-resolution cryo-EM structure determination in RELION-3 , 2018, eLife.
[17] B. Antonny,et al. The Many Faces of Amphipathic Helices , 2018, Biomolecules.
[18] K. Ueda,et al. Temporary sequestration of cholesterol and phosphatidylcholine within extracellular domains of ABCA1 during nascent HDL generation , 2018, Scientific Reports.
[19] M. Phillips. Is ABCA1 a lipid transfer protein? , 2018, Journal of Lipid Research.
[20] T. Walz,et al. Structural basis of MsbA-mediated lipopolysaccharide transport , 2017, Nature.
[21] X. Gong,et al. Structure of the Human Lipid Exporter ABCA1 , 2017, Cell.
[22] U. Hellmich,et al. Diverse relations between ABC transporters and lipids: An overview. , 2017, Biochimica et biophysica acta. Biomembranes.
[23] S. Hazen,et al. PI(4,5)P2 Is Translocated by ABCA1 to the Cell Surface Where It Mediates Apolipoprotein A1 Binding and Nascent HDL Assembly. , 2016, Circulation research.
[24] M. Lindén,et al. Anisotropic Membrane Curvature Sensing by Amphipathic Peptides. , 2014, Biophysical journal.
[25] R. Marschalek,et al. Optimized Sleeping Beauty transposons rapidly generate stable transgenic cell lines. , 2015, Biotechnology journal.
[26] E. Favari,et al. Cholesterol efflux and reverse cholesterol transport. , 2015, Handbook of experimental pharmacology.
[27] Toni Giorgino,et al. MEMBPLUGIN: studying membrane complexity in VMD , 2014, Bioinform..
[28] R. Molday,et al. Differential Phospholipid Substrates and Directional Transport by ATP-binding Cassette Proteins ABCA1, ABCA7, and ABCA4 and Disease-causing Mutants*♦ , 2013, The Journal of Biological Chemistry.
[29] S. Hazen,et al. ABCA1 Mediates Unfolding of Apolipoprotein AI N Terminus on the Cell Surface Before Lipidation and Release of Nascent High-Density Lipoprotein , 2013, Arteriosclerosis, thrombosis, and vascular biology.
[30] A. Kusumi,et al. ABCA1 dimer–monomer interconversion during HDL generation revealed by single-molecule imaging , 2013, Proceedings of the National Academy of Sciences.
[31] N. Fitz,et al. Abca1 Deficiency Affects Alzheimer's Disease-Like Phenotype in Human ApoE4 But Not in ApoE3-Targeted Replacement Mice , 2012, The Journal of Neuroscience.
[32] Eric Gouaux,et al. A fluorescence-detection size-exclusion chromatography-based thermostability assay for membrane protein precrystallization screening. , 2012, Structure.
[33] M. Hayden,et al. Increased risk of coronary artery disease in Caucasians with extremely low HDL cholesterol due to mutations in ABCA1, APOA1, and LCAT. , 2012, Biochimica et biophysica acta.
[34] K. Ueda,et al. ATP hydrolysis-dependent conformational changes in the extracellular domain of ABCA1 are associated with apoA-I binding[S] , 2012, Journal of Lipid Research.
[35] R. Bittman,et al. A sensitive assay for ABCA1-mediated cholesterol efflux using BODIPY-cholesterol , 2011, Journal of Lipid Research.
[36] D. Higgins,et al. Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega , 2011, Molecular systems biology.
[37] G. Voth,et al. Mechanism of membrane curvature sensing by amphipathic helix containing proteins. , 2011, Biophysical journal.
[38] E. Tajkhorshid,et al. Conformational coupling of the nucleotide-binding and the transmembrane domains in ABC transporters. , 2009, Biophysical journal.
[39] B. Fadeel,et al. The ins and outs of phospholipid asymmetry in the plasma membrane: roles in health and disease , 2009, Critical reviews in biochemistry and molecular biology.
[40] K. Ueda,et al. Formation of Two Intramolecular Disulfide Bonds Is Necessary for ApoA-I-dependent Cholesterol Efflux Mediated by ABCA1* , 2009, Journal of Biological Chemistry.
[41] A. Vaughan,et al. ABCA1 mutants reveal an interdependency between lipid export function, apoA-I binding activity, and Janus kinase 2 activation ** This work was supported by National Institutes of Health Grant RO1HL-55362. Published, JLR Papers in Press, September 5, 2008. , 2009, Journal of Lipid Research.
[42] Andreas Engel,et al. Structure and mechanics of membrane proteins. , 2008, Annual review of biochemistry.
[43] A. Tall,et al. HDL, ABC transporters, and cholesterol efflux: implications for the treatment of atherosclerosis. , 2008, Cell metabolism.
[44] G. Meer,et al. Membrane lipids: where they are and how they behave , 2008, Nature Reviews Molecular Cell Biology.
[45] Amy B. Ghering,et al. ABCA1-Induced Cell Surface Binding Sites for ApoA-I , 2007, Arteriosclerosis, thrombosis, and vascular biology.
[46] A. Vaughan,et al. ATP-binding Cassette Transporter A1 Expression Disrupts Raft Membrane Microdomains through Its ATPase-related Functions* , 2006, Journal of Biological Chemistry.
[47] A. Vaughan,et al. ATP-Binding cassette cholesterol transporters and cardiovascular disease. , 2006, Circulation research.
[48] Elina Ikonen,et al. Mechanisms for cellular cholesterol transport: defects and human disease. , 2006, Physiological reviews.
[49] M. Phillips,et al. Characterization of nascent HDL particles and microparticles formed by ABCA1-mediated efflux of cellular lipids to apoA-I Published, JLR Papers in Press, January 17, 2006. , 2006, Journal of Lipid Research.
[50] Paul Curnow,et al. Membrane proteins, lipids and detergents: not just a soap opera. , 2004, Biochimica et biophysica acta.
[51] A. Horwitz,et al. ABCA1 mediates concurrent cholesterol and phospholipid efflux to apolipoprotein A-I Published, JLR Papers in Press, January 1, 2004. DOI 10.1194/jlr.M300336-JLR200 , 2004, Journal of Lipid Research.
[52] M. Freeman,et al. ABCA1 and amphipathic apolipoproteins form high-affinity molecular complexes required for cholesterol efflux Published, JLR Papers in Press, November 16, 2003. DOI 10.1194/jlr.M300355-JLR200 , 2004, Journal of Lipid Research.
[53] S. Yokoyama,et al. Effects of Mutations of ABCA1 in the First Extracellular Domain on Subcellular Trafficking and ATP Binding/Hydrolysis* 210 , 2003, The Journal of Biological Chemistry.
[54] A. von Eckardstein,et al. The Central Helices of ApoA-I Can Promote ATP-binding Cassette Transporter A1 (ABCA1)-mediated Lipid Efflux , 2003, The Journal of Biological Chemistry.
[55] S. Witting,et al. The Role of Apolipoprotein A-I Helix 10 in Apolipoprotein-mediated Cholesterol Efflux via the ATP-binding Cassette Transporter ABCA1* , 2002, The Journal of Biological Chemistry.
[56] M. Freeman,et al. Naturally Occurring Mutations in the Largest Extracellular Loops of ABCA1 Can Disrupt Its Direct Interaction with Apolipoprotein A-I* , 2002, The Journal of Biological Chemistry.
[57] J. Dietschy,et al. Cholesterol metabolism in the brain , 2001, Current opinion in lipidology.
[58] H. Rigneault,et al. Specific Docking of Apolipoprotein A-I at the Cell Surface Requires a Functional ABCA1 Transporter* , 2001, The Journal of Biological Chemistry.
[59] A. Rzhetsky,et al. The human ATP-binding cassette (ABC) transporter superfamily. , 2001, Genome research.
[60] R. Lawn,et al. ABCA1 Is the cAMP-inducible Apolipoprotein Receptor That Mediates Cholesterol Secretion from Macrophages* , 2000, The Journal of Biological Chemistry.
[61] A. Tall,et al. Specific Binding of ApoA-I, Enhanced Cholesterol Efflux, and Altered Plasma Membrane Morphology in Cells Expressing ABC1* , 2000, The Journal of Biological Chemistry.
[62] A. Vaughan,et al. The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway. , 1999, The Journal of clinical investigation.
[63] T. Langmann,et al. Molecular cloning of the human ATP-binding cassette transporter 1 (hABC1): evidence for sterol-dependent regulation in macrophages. , 1999, Biochemical and biophysical research communications.
[64] K. Marheineke,et al. Lipid composition of Spodoptera frugiperda (Sf9) and Trichoplusia ni (Tn) insect cells used for baculovirus infection , 1998, FEBS letters.
[65] F. Maxfield,et al. Cholesterol distribution in living cells: fluorescence imaging using dehydroergosterol as a fluorescent cholesterol analog. , 1998, Biophysical journal.
[66] K Schulten,et al. VMD: visual molecular dynamics. , 1996, Journal of molecular graphics.
[67] F. Denizot,et al. Cloning of two novel ABC transporters mapping on human chromosome 9. , 1994, Genomics.
[68] A A Spector,et al. Membrane lipid composition and cellular function. , 1985, Journal of lipid research.
[69] W. Higuchi,et al. Water solubility of cholesterol. , 1965, Journal of pharmaceutical sciences.