Replication of linkage on chromosome 7q22 and association of the regional Reelin gene with working memory in schizophrenia families

[1]  J. Suvisaari,et al.  Impaired executive performance in healthy siblings of schizophrenia patients in a population-based study , 2007, Schizophrenia Research.

[2]  Raquel E Gur,et al.  The Consortium on the Genetics of Schizophrenia: neurocognitive endophenotypes. , 2006, Schizophrenia bulletin.

[3]  Robert Freedman,et al.  Deconstructing schizophrenia: an overview of the use of endophenotypes in order to understand a complex disorder. , 2006, Schizophrenia bulletin.

[4]  J. Suvisaari,et al.  Lifetime prevalence of psychotic and bipolar I disorders in a general population. , 2007, Archives of general psychiatry.

[5]  A. Guidotti,et al.  Reelin down-regulation in mice and psychosis endophenotypes , 2006, Neuroscience & Biobehavioral Reviews.

[6]  S. Deutsch,et al.  Dysregulation of tau phosphorylation is a hypothesized point of convergence in the pathogenesis of alzheimer's disease, frontotemporal dementia and schizophrenia with therapeutic implications , 2006, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[7]  Brien Riley,et al.  Molecular genetic studies of schizophrenia , 2006, European Journal of Human Genetics.

[8]  E. Weeber,et al.  Cognitive disruption and altered hippocampus synaptic function in Reelin haploinsufficient mice , 2006, Neurobiology of Learning and Memory.

[9]  Chiara Sabatti,et al.  Magnitude and distribution of linkage disequilibrium in population isolates and implications for genome-wide association studies , 2006, Nature Genetics.

[10]  P. Buckley.  Genotype–Environment Interaction in Schizophrenia-Spectrum Disorder: Long-term Follow-up Study of Finnish Adoptees , 2006 .

[11]  M J Owen,et al.  Schizophrenia: genes at last? , 2005, Trends in genetics : TIG.

[12]  Gonçalo R. Abecasis,et al.  PEDSTATS: descriptive statistics, graphics and quality assessment for gene mapping data , 2005, Bioinform..

[13]  A. Guidotti,et al.  Reelin promoter hypermethylation in schizophrenia. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[14]  A. Addington,et al.  The neurodevelopmental model of schizophrenia: update 2005 , 2005, Molecular Psychiatry.

[15]  Daniel E. Weeks,et al.  Mega2: data-handling for facilitating genetic linkage and association analyses , 2005, Bioinform..

[16]  M. Owen,et al.  No evidence for association between polymorphisms in GRM3 and schizophrenia , 2005, BMC psychiatry.

[17]  J L Rapoport,et al.  The neurodevelopmental model of schizophrenia: update 2005 , 2005, Molecular Psychiatry.

[18]  J. McGrath,et al.  A Systematic Review of the Prevalence of Schizophrenia , 2005, PLoS medicine.

[19]  S. Faraone,et al.  Hypermethylation of the reelin (RELN) promoter in the brain of schizophrenic patients: A preliminary report , 2005, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[20]  Tyrone D. Cannon,et al.  The inheritance of intermediate phenotypes for schizophrenia , 2005, Current opinion in psychiatry.

[21]  S. Fatemi,et al.  Reelin glycoprotein: structure, biology and roles in health and disease , 2005, Molecular Psychiatry.

[22]  G. He,et al.  A case-control study of the relationship between the metabotropic glutamate receptor 3 gene and schizophrenia in the Chinese population , 2005, Schizophrenia Research.

[23]  Markus Perola,et al.  AUTOGSCAN: powerful tools for automated genome-wide linkage and linkage disequilibrium analysis. , 2005, Twin research and human genetics : the official journal of the International Society for Twin Studies.

[24]  Mark Daly,et al.  Haploview: analysis and visualization of LD and haplotype maps , 2005, Bioinform..

[25]  Paul J. Harrison,et al.  Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence , 2005, Molecular Psychiatry.

[26]  Matcheri S. Keshavan,et al.  Correlates of insight in first episode psychosis , 2004, Schizophrenia Research.

[27]  J. Suvisaari,et al.  Age at onset and cognitive functioning in schizophrenia , 2004, British Journal of Psychiatry.

[28]  R. Gibbs,et al.  Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[29]  Tyrone D. Cannon,et al.  Search for cognitive trait components of schizophrenia reveals a locus for verbal learning and memory on 4q and for visual working memory on 2q. , 2004, Human molecular genetics.

[30]  Leena Peltonen,et al.  Isolates and their potential use in complex gene mapping efforts. , 2004, Current opinion in genetics & development.

[31]  J. Suvisaari,et al.  Clinical phenotype of schizophrenia in a Finnish isolate , 2004, Schizophrenia Research.

[32]  M C O'Donovan,et al.  The molecular genetics of schizophrenia: new findings promise new insights , 2004, Molecular Psychiatry.

[33]  Alberto Riva,et al.  A SNP-centric database for the investigation of the human genome , 2004, BMC Bioinformatics.

[34]  Toshihiro Tanaka.  The International HapMap Project , 2003, Nature.

[35]  Leena Peltonen,et al.  Haplotype transmission analysis provides evidence of association for DISC1 to schizophrenia and suggests sex-dependent effects. , 2003, Human molecular genetics.

[36]  Tao Li,et al.  The genetics of schizophrenia: glutamate not dopamine? , 2003, European journal of pharmacology.

[37]  Y. Fukumaki,et al.  Positive associations of polymorphisms in the metabotropic glutamate receptor type 3 gene (GRM3) with schizophrenia , 2003, Psychiatric genetics.

[38]  R. Kahn,et al.  Sex differences in the risk of schizophrenia: evidence from meta-analysis. , 2003, Archives of general psychiatry.

[39]  I. Gottesman,et al.  The endophenotype concept in psychiatry: etymology and strategic intentions. , 2003, The American journal of psychiatry.

[40]  Paul J. Harrison,et al.  Interstitial white matter neurons express less reelin and are abnormally distributed in schizophrenia: towards an integration of molecular and morphologic aspects of the neurodevelopmental hypothesis , 2003, Molecular Psychiatry.

[41]  Paul J. Harrison,et al.  The axonal chemorepellant semaphorin 3A is increased in the cerebellum in schizophrenia and may contribute to its synaptic pathology , 2003, Molecular Psychiatry.

[42]  T. Paunio,et al.  The interval of linkage disequilibrium (LD) detected with microsatellite and SNP markers in chromosomes of Finnish populations with different histories. , 2003, Human molecular genetics.

[43]  Tyrone D. Cannon,et al.  Heritability and number of quantitative trait loci of neurocognitive functions in families with schizophrenia. , 2002, American journal of medical genetics.

[44]  Tom H. Pringle,et al.  The human genome browser at UCSC. , 2002, Genome research.

[45]  Hong-jun Song,et al.  Knowing How to Navigate: Mechanisms of Semaphorin Signaling in the Nervous System , 2002, Science's STKE.

[46]  A. Guidotti,et al.  REELIN and schizophrenia: a disease at the interface of the genome and the epigenome. , 2002, Molecular interventions.

[47]  Jeanette C Papp,et al.  Detection and integration of genotyping errors in statistical genetics. , 2002, American journal of human genetics.

[48]  S. Cichon,et al.  Metabotropic glutamate receptor 3 (GRM3) gene variation is not associated with schizophrenia or bipolar affective disorder in the German population. , 2002, American journal of medical genetics.

[49]  G. Abecasis,et al.  Merlin—rapid analysis of dense genetic maps using sparse gene flow trees , 2002, Nature Genetics.

[50]  D. Garlick.  Understanding the nature of the general factor of intelligence: the role of individual differences in neural plasticity as an explanatory mechanism. , 2002, Psychological review.

[51]  J D Terwilliger,et al.  Genome-wide scan in a nationwide study sample of schizophrenia families in Finland reveals susceptibility loci on chromosomes 2q and 5q. , 2001, Human molecular genetics.

[52]  D E Weeks,et al.  Multipoint Estimation of Identity-by-Descent Probabilities at Arbitrary Positions among Marker Loci on General Pedigrees , 2001, Human Heredity.

[53]  I. Gottesman,et al.  Family and twin strategies as a head start in defining prodromes and endophenotypes for hypothetical early-interventions in schizophrenia , 2001, Schizophrenia Research.

[54]  J S Sinsheimer,et al.  Chromosome 1 loci in Finnish schizophrenia families. , 2001, Human molecular genetics.

[55]  S. Fatemi,et al.  Reelin mutations in mouse and man: from reeler mouse to schizophrenia, mood disorders, autism and lissencephaly , 2001, Molecular Psychiatry.

[56]  D. Jeste,et al.  Stability and course of neuropsychological deficits in schizophrenia. , 2001, Archives of general psychiatry.

[57]  T. Curran,et al.  Role of the reelin signaling pathway in central nervous system development. , 2001, Annual review of neuroscience.

[58]  Kenneth Lange,et al.  Use of population isolates for mapping complex traits , 2000, Nature Reviews Genetics.

[59]  Yogesh K. Dwivedi,et al.  Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: a postmortem brain study. , 2000, Archives of general psychiatry.

[60]  L. Peltonen,et al.  Linkage disequilibrium in isolated populations: Finland and a young sub-population of Kuusamo , 2000, European Journal of Human Genetics.

[61]  R. Possenti,et al.  VGF: A Novel Role for This Neuronal and Neuroendocrine Polypeptide in the Regulation of Energy Balance , 2000, Frontiers in Neuroendocrinology.

[62]  J. Suvisaari,et al.  Genome-wide scan for schizophrenia in the Finnish population: evidence for a locus on chromosome 7q22. , 2000, Human molecular genetics.

[63]  H H Göring,et al.  Linkage analysis in the presence of errors IV: joint pseudomarker analysis of linkage and/or linkage disequilibrium on a mixture of pedigrees and singletons when the mode of inheritance cannot be accurately specified. , 2000, American journal of human genetics.

[64]  I. Gottesman,et al.  Twin studies of schizophrenia: from bow-and-arrow concordances to star wars Mx and functional genomics. , 2000, American journal of medical genetics.

[65]  Gonçalo R. Abecasis,et al.  GOLD-Graphical Overview of Linkage Disequilibrium , 2000, Bioinform..

[66]  T. Goldberg,et al.  Cognitive impairment in schizophrenia is the core of the disorder. , 2000, Critical reviews in neurobiology.

[67]  G. Abecasis,et al.  A general test of association for quantitative traits in nuclear families. , 2000, American journal of human genetics.

[68]  T. Curran,et al.  Mutant mice with scrambled brains: understanding the signaling pathways that control cell positioning in the CNS. , 1999, Genes & development.

[69]  D. Clayton,et al.  A generalization of the transmission/disequilibrium test for uncertain-haplotype transmission. , 1999, American journal of human genetics.

[70]  J. Suvisaari,et al.  A genomewide screen for schizophrenia genes in an isolated Finnish subpopulation, suggesting multiple susceptibility loci. , 1999, American journal of human genetics.

[71]  Jonathan A. Cooper,et al.  Lipoprotein Receptors Signaling Functions in the Brain? , 1999, Cell.

[72]  A D Paterson,et al.  Schizophrenia: an epigenetic puzzle? , 1999, Schizophrenia bulletin.

[73]  T Varilo,et al.  Molecular genetics of the Finnish disease heritage. , 1999, Human molecular genetics.

[74]  Yogesh K. Dwivedi,et al.  A decrease of reelin expression as a putative vulnerability factor in schizophrenia. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[75]  J R O'Connell,et al.  PedCheck: a program for identification of genotype incompatibilities in linkage analysis. , 1998, American journal of human genetics.

[76]  J. Suvisaari,et al.  Schizophrenia in the genetic isolate of Finland. , 1997, American journal of medical genetics.

[77]  K Lange,et al.  Descent graphs in pedigree analysis: applications to haplotyping, location scores, and marker-sharing statistics. , 1996, American journal of human genetics.

[78]  Joseph T. Coyle,et al.  The Glutamatergic Dysfunction Hypothesis for Schizophrenia , 1996, Harvard review of psychiatry.

[79]  R. Possenti,et al.  Tissue‐Specific Processing of the Neuroendocrine Protein VGF , 1995, Journal of neurochemistry.

[80]  L. Excoffier,et al.  Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population. , 1995, Molecular biology and evolution.

[81]  L. Maffei,et al.  A developmentally regulated nerve growth factor-induced gene, VGF, is expressed in geniculocortical afferents during synaptogenesis , 1995, Neuroscience.

[82]  K. Kendler,et al.  The Roscommon Family Study. I. Methods, diagnosis of probands, and risk of schizophrenia in relatives. , 1993, Archives of general psychiatry.

[83]  A. Farmer,et al.  A polydiagnostic application of operational criteria in studies of psychotic illness. Development and reliability of the OPCRIT system. , 1991, Archives of general psychiatry.

[84]  K. Dong,et al.  Structure of the gene encoding VGF, a nervous system-specific mRNA that is rapidly and selectively induced by nerve growth factor in PC12 cells , 1991, Molecular and cellular biology.

[85]  K Y Liang,et al.  Longitudinal data analysis for discrete and continuous outcomes. , 1986, Biometrics.

[86]  Richard J. Haier,et al.  Schizophrenia: The epigenetic puzzle Cambridge University Press, Cambridge (1982). 258 pp. by Irving I. Gottesman and James Shields , 1982, Psychiatry Research.

[87]  D. Wechsler.  WAIS-R manual : Wechsler adult intelligence scale-revised , 1981 .

[88]  Christie Golden,et al.  Stroop Color and Word Test: Manual for Clinical and Experimental Uses. , 1978 .

[89]  N. Blin,et al.  A general method for isolation of high molecular weight DNA from eukaryotes. , 1976, Nucleic acids research.

[90]  J. Perheentupa,et al.  Hereditary diseases in Finland; rare flora in rare soul. , 1973, Annals of clinical research.