Calcified Cystic Lesions in a Patient with Epilepsy and Progressive Dementia

A 67‐year‐old woman had intractable epilepsy and developed a progressive dementia with upper motor neuron signs over the last 6 years Magnetic resonance imaging (MRI) revealed multiple areas of large calcified cysts, which increased in number and size over the last 3 years. Discussion includes the appearance of these lesions radiologically and pathologically, as well as their differential diagnosis and clinical significance, focusing on the increasing detection of these lesions with current imaging techniques.

[1]  J. Golden,et al.  Appearance of a cavernous hemangioma in the cerebral cortex after a biopsy of a deeper lesion. , 1993, Neurosurgery.

[2]  C. Sila,et al.  Progressive vision loss. A rare manifestation of familial cavernous angiomas. , 1992, Archives of neurology.

[3]  M. Hadley,et al.  Cavernous malformations and capillary telangiectasia: a spectrum within a single pathological entity. , 1991, Neurosurgery.

[4]  E. Pozzati,et al.  The growth of cerebral cavernous angiomas. , 1989, Neurosurgery.

[5]  M. Hadley,et al.  Cerebral cavernous malformations. Incidence and familial occurrence. , 1988, The New England journal of medicine.

[6]  H. Steiger,et al.  Clinicopathological relations of cerebral cavernous angiomas: observations in eleven cases. , 1987, Neurosurgery.

[7]  M. Hadley,et al.  The MRI appearance of cavernous malformations (angiomas). , 1987, Journal of neurosurgery.

[8]  G. Forbes,et al.  Familial cavernous malformations of the central nervous system and retina , 1987, Annals of neurology.

[9]  J. Simard,et al.  Cavernous angioma: a review of 126 collected and 12 new clinical cases. , 1986, Neurosurgery.

[10]  G. Oliveri,et al.  Cystic cavernous angiomas of the posterior fossa. Report of three cases. , 1985, Journal of neurosurgery.

[11]  R. Wilkins.  Natural History of Intracranial Vascular Malformations: A Review , 1985, Neurosurgery.

[12]  L. Hayman,et al.  Familial cavernous angiomas: natural history and genetic study over a 5-year period. , 1982, American journal of medical genetics.

[13]  D. Vonofakos,et al.  Cystic cerebral cavernous angioma with dense calcification. Case report. , 1980, Journal of neurosurgery.

[14]  V. Kasantikul,et al.  Combined neurilemmoma and angioma. Tumor of ectomesenchyme and a source of bleeding. , 1979, Journal of neurosurgery.

[15]  F. Sklar,et al.  Multiple small cavernous angiomas of the brain with increased intracranial pressure , 1978, Annals of neurology.

[16]  J. Selhorst,et al.  Blue rubber bleb nevus syndrome with CNS involvement and thrombosis of a vein of galen malformation , 1978, Annals of neurology.

[17]  J. Lenihan,et al.  LEAD IN CHILDREN'S HAIR , 1976, The Lancet.

[18]  K. Voigt,et al.  Cerebral Cavernous Haemangiomas or Cavernomas , 1976, Neurochirurgia.

[19]  J. Clark.  Familial occurrence of cavernous angiomata of the brain , 1970, Journal of neurology, neurosurgery, and psychiatry.

[20]  J. Sená.  [Cavernous hemangioma of the orbit]. , 1954, El Dia medico.

[21]  J. Cumings,et al.  Cerebral angiomata in an Icelandic family. , 1947, Lancet.