Instrumentation for electroretinography: a LED-based stimulator

In the field of Electroretinography (ERG), new clinical studies begin to show interesting applications of the harmonic analysis of electrophysiological signals obtained in response to flicker-type stimulation of the central retina (macula). The clinical information within this type of signal can be fully exploited only if the experiments are performed using high quality devices, having low distortion and a wide operation range for the stimulation parameters. In this view we developed a stand-alone stimulator that takes advantage from the use of recent optoelectronic devices (the ultra-bright LEDs) and embedded microprocessor control. The instrument, being of simple and reliable operation, was intended as a mean to encourage the introduction of some of the most recent and interesting results of neurophysiological and psychophysical research in the eye clinic.

[1]  C. Baker,et al.  Linear and nonlinear components of human electroretinogram. , 1984, Journal of neurophysiology.

[2]  A. Elsner,et al.  Analysis of nonlinearities in the flicker ERG. , 1992, Optometry and vision science : official publication of the American Academy of Optometry.

[3]  V. Porciatti,et al.  Postreceptoral contribution to macular dysfunction in retinitis pigmentosa. , 1994, Investigative ophthalmology & visual science.

[4]  V Porciatti,et al.  Development of personal computer software for a visual electrophysiology laboratory. , 1989, Computer methods and programs in biomedicine.

[5]  R. Carr,et al.  Evaluating macular function using the focal ERG. , 1986, Investigative ophthalmology & visual science.

[6]  C. Baker,et al.  Current source density analysis of linear and non‐linear components of the primate electroretinogram. , 1988, The Journal of physiology.

[7]  M. Alpern,et al.  Electroretinograms evoked by sinusoidal excitation of human cones. , 1985, The Journal of physiology.