DNA copy number losses in human neoplasms.

[1]  L. Dubeau,et al.  Suppression of tumorigenicity in human ovarian cancer cell lines is controlled by a 2 cM fragment in chromosomal region 6q24-q25 , 1999, Oncogene.

[2]  I. Bièche,et al.  Study of FHIT transcripts in normal and malignant breast tissue , 1998, Genes, chromosomes & cancer.

[3]  M. Ittmann.  Chromosome 10 alterations in prostate adenocarcinoma (review). , 1998, Oncology reports.

[4]  D. Lane,et al.  The p53 tumour suppressor gene , 1998, The British journal of surgery.

[5]  Shahrooz Rabizadeh,et al.  The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysis , 1998, Nature.

[6]  J. Minna,et al.  Alterations of the PPP2R1B gene in human lung and colon cancer. , 1998, Science.

[7]  G. Chenevix-Trench,et al.  Frequent loss of heterozygosity and three critical regions on the short arm of chromosome 8 in ovarian adenocarcinomas , 1998, Oncogene.

[8]  Kenji Suzuki,et al.  Loss of heterozygosity in the tuberous sclerosis gene associated regions in adenocarcinoma of the lung accompanied by multiple atypical adenomatous hyperplasia , 1998, International journal of cancer.

[9]  F. Apiou,et al.  hZAC encodes a zinc finger protein with antiproliferative properties and maps to a chromosomal region frequently lost in cancer. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[10]  P Hunt,et al.  Localization of tumor suppressor activity important in nonsmall cell lung carcinoma on chromosome 11q. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[11]  M. Fernö,et al.  Genetic aberrations in hypodiploid breast cancer: frequent loss of chromosome 4 and amplification of cyclin D1 oncogene. , 1998, The American journal of pathology.

[12]  A. Sakurada,et al.  The H-cadherin (CDH13) gene is inactivated in human lung cancer , 1998, Human Genetics.

[13]  J. Minna,et al.  Cloning of a breast cancer homozygous deletion junction narrows the region of search for a 3p21.3 tumor suppressor gene , 1998, Oncogene.

[14]  S. Thorgeirsson,et al.  Cloning, characterization, and chromosomal localization of a gene frequently deleted in human liver cancer (DLC-1) homologous to rat RhoGAP. , 1998, Cancer research.

[15]  S. Knuutila,et al.  DNA copy number amplifications in human neoplasms: review of comparative genomic hybridization studies. , 1998, The American journal of pathology.

[16]  P. Deloukas,et al.  A detailed physical and transcriptional map of the region of chromosome 20 that is deleted in myeloproliferative disorders and refinement of the common deleted region. , 1998, Genomics.

[17]  P. Neiman,et al.  A widely expressed transcription factor with multiple DNA sequence specificity, CTCF, is localized at chromosome segment 16q22.1 within one of the smallest regions of overlap for common deletions in breast and prostate cancers , 1998, Genes, chromosomes & cancer.

[18]  B. Simon,et al.  Frequent abnormalities of the putative tumor suppressor gene FHIT at 3p14.2 in pancreatic carcinoma cell lines. , 1998, Cancer research.

[19]  K. Franssila,et al.  Gain of 3q and deletion of 11q22 are frequent aberrations in mantle cell lymphoma , 1998, Genes, chromosomes & cancer.

[20]  M. L. Le Beau,et al.  An FHIT tumor suppressor gene? , 1998, Genes, chromosomes & cancer.

[21]  P. Nowell,et al.  Molecular anatomy of chromosome 7q deletions in myeloid neoplasms: evidence for multiple critical loci. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[22]  Patricia A. Elder,et al.  Structure and methylation-based silencing of a gene (DBCCR1) within a candidate bladder cancer tumor suppressor region at 9q32-q33. , 1998, Genomics.

[23]  Hiroyuki Miyoshi,et al.  Intestinal Tumorigenesis in Compound Mutant Mice of both Dpc4(Smad4) and Apc Genes , 1998, Cell.

[24]  K. Kinzler,et al.  Targeted deletion of Smad4 shows it is required for transforming growth factor beta and activin signaling in colorectal cancer cells. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[25]  D. Sidransky,et al.  Role of the p16 tumor suppressor gene in cancer. , 1998, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[26]  J Chang-Claude,et al.  Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium. , 1998, American journal of human genetics.

[27]  A. Giordano,et al.  Expression of the retinoblastoma-related gene Rb2/p130 correlates with clinical outcome in endometrial cancer. , 1998, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[28]  Shizuo Akira,et al.  ZIP Kinase, a Novel Serine/Threonine Kinase Which Mediates Apoptosis , 1998, Molecular and Cellular Biology.

[29]  Peter Lichter,et al.  Minimal sizes of deletions detected by comparative genomic hybridization , 1998, Genes, chromosomes & cancer.

[30]  M. Stoffel,et al.  Refinement of the commonly deleted segment in myeloid leukemias with a del(20q) , 1998, Genes, chromosomes & cancer.

[31]  F. Speleman,et al.  Identification of a third EXT-like gene (EXTL3) belonging to the EXT gene family. , 1998, Genomics.

[32]  M. Edelson,et al.  A one centimorgan deletion unit on chromosome Xq12 is commonly lost in borderline and invasive epithelial ovarian tumors , 1998, Oncogene.

[33]  M. Stratton,et al.  A serine/threonine kinase gene defective in Peutz–Jeghers syndrome , 1998, Nature.

[34]  S. Knuutila,et al.  Optimization of comparative genomic hybridization using fluorochrome conjugated to dCTP and dUTP nucleotides. , 1997, Laboratory investigation; a journal of technical methods and pathology.

[35]  David I. Smith,et al.  Loss of heterozygosity on the long arm of human chromosome 7 in sporadic renal cell carcinomas , 1997, Oncogene.

[36]  A. Winterpacht,et al.  Loss of heterozygosity studies and deletion mapping identify two putative chromosome 14q tumor suppressor loci in renal oncocytomas. , 1997, Cancer research.

[37]  E. Zabarovsky,et al.  Cloning of two candidate tumor suppressor genes within a 10 kb region on chromosome 13q14, frequently deleted in chronic lymphocytic leukemia , 1997, Oncogene.

[38]  A. Berchuck,et al.  Loss of heterozygosity at chromosome segment Xq25‐26.1 in advanced human ovarian carcinomas , 1997, Genes, chromosomes & cancer.

[39]  A. Westerveld,et al.  Fine mapping of a region of common deletion on chromosome arm 10p in human glioma , 1997, Genes, chromosomes & cancer.

[40]  O. Cummings,et al.  Inactivation of Smad4 in gastric carcinomas. , 1997, Cancer research.

[41]  A. Giordano,et al.  Differential expression of Rb2/p130 and p107 in normal human tissues and in primary lung cancer. , 1997, Clinical cancer research : an official journal of the American Association for Cancer Research.

[42]  K. Kinzler,et al.  A model for p53-induced apoptosis , 1997, Nature.

[43]  S. Jhanwar,et al.  Multiple regions of allelic loss from chromosome arm 6q in malignant mesothelioma. , 1997, Cancer research.

[44]  Kathleen R. Cho,et al.  Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies. , 1997, Cancer research.

[45]  W. Kaelin,et al.  p73 is a human p53-related protein that can induce apoptosis , 1997, Nature.

[46]  A. Green,et al.  Mutations in the TSC2 gene: analysis of the complete coding sequence using the protein truncation test (PTT). , 1997, Human molecular genetics.

[47]  H. Cavé,et al.  ETV6 is the target of chromosome 12p deletions in t(12;21) childhood acute lymphocytic leukemia , 1997, Leukemia.

[48]  F. Waldman,et al.  Chromosome 8p deletions are associated with invasive tumor growth in urinary bladder cancer. , 1997, The American journal of pathology.

[49]  J. Boyd,et al.  Mutation analysis of the putative tumor suppressor gene PTEN/MMAC1 in primary breast carcinomas. , 1997, Cancer research.

[50]  A. Yang,et al.  Monoallelically Expressed Gene Related to p53 at 1p36, a Region Frequently Deleted in Neuroblastoma and Other Human Cancers , 1997, Cell.

[51]  L. Reid,et al.  Localization of a putative liver tumor suppressor locus to a 950‐kb region of human 11p11.2‐p12 using rat liver tumor microcell hybrid cell lines , 1997, Molecular carcinogenesis.

[52]  O. Kallioniemi,et al.  Frequent loss of the 11q14‐24 region in chronic lymphocytic leukemia: A study by comparative genomic hybridization , 1997, Genes, chromosomes & cancer.

[53]  D. Gilliland,et al.  TEL is one of the targets for deletion on 12p in many cases of childhood B-lineage acute lymphoblastic leukemia , 1997, Leukemia.

[54]  Maria Grazia Valsecchi,et al.  Incidence and clinical relevance of TEL/AML1 fusion genes in children with acute lymphoblastic leukemia enrolled in the German and Italian multicenter therapy trials , 1997 .

[55]  H. Moch,et al.  Marked genetic differences between stage pTa and stage pT1 papillary bladder cancer detected by comparative genomic hybridization. , 1997, Cancer research.

[56]  U. Surti,et al.  Two discrete regions of deletion at 7q in uterine leiomyomas , 1997, Genes, chromosomes & cancer.

[57]  Hiroyuki Yamamoto,et al.  Association of reduced cell adhesion regulator messenger RNA expression with tumor progression in human hepatocellular carcinoma , 1997, International journal of cancer.

[58]  S. Scherer,et al.  Identification of a 1300 kilobase deletion unit on chromosome 7q31.3 in invasive epithelial ovarian carcinomas , 1997, Oncogene.

[59]  G. Giaccone,et al.  FHIT and FRA3B 3p14.2 allele loss are common in lung cancer and preneoplastic bronchial lesions and are associated with cancer-related FHIT cDNA splicing aberrations. , 1997, Cancer research.

[60]  M. Knowles,et al.  A novel candidate tumour suppressor locus at 9q32-33 in bladder cancer: localization of the candidate region within a single 840 kb YAC. , 1997, Human molecular genetics.

[61]  R. Young,et al.  BRCA1 is a component of the RNA polymerase II holoenzyme. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[62]  M. Zeremski,et al.  Localization of the candidate tumor suppressor geneING1 to human chromosome 13q34 , 1997, Somatic cell and molecular genetics.

[63]  P. Bugert,et al.  Significance of chromosome arm 14q loss in nonpapillary renal cell carcinomas , 1997, Genes, chromosomes & cancer.

[64]  M. Horstmann,et al.  Frequent reduction or loss of DCC gene expression in human osteosarcoma. , 1997, British Journal of Cancer.

[65]  A. Godwin,et al.  Identification of a zinc-finger gene at 6q25: a chromosomal region implicated in development of many solid tumors , 1997, Oncogene.

[66]  M. Minden,et al.  Defects of the mismatch repair gene MSH2 are implicated in the development of murine and human lymphoblastic lymphomas and are associated with the aberrant expression of rhombotin-2 (Lmo-2) and Tal-1 (SCL). , 1997, Blood.

[67]  J Isola,et al.  Distinct somatic genetic changes associated with tumor progression in carriers of BRCA1 and BRCA2 germ-line mutations. , 1997, Cancer research.

[68]  M. Wigler,et al.  PTEN, a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer , 1997, Science.

[69]  J. Downing,et al.  TEL gene rearrangement in acute lymphoblastic leukemia: a new genetic marker with prognostic significance. , 1997, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[70]  A. Børresen-Dale,et al.  Loss of heterozygosity at 11q23.1 in breast carcinomas: Indication for involvement of a gene distal and close to ATM , 1997, Genes, chromosomes & cancer.

[71]  P. Schlag,et al.  Strong indication for a breast cancer susceptibility gene on chromosome 8p12-p22: linkage analysis in German breast cancer families , 1997, Oncogene.

[72]  M. Morgan,et al.  Deletion mapping of two potential chromosome 14 tumor suppressor gene loci in ovarian carcinoma. , 1997, Cancer research.

[73]  C. Bakkenist,et al.  Allelic deletions at chromosome 11q22-q23.1 and 11q25-qterm are frequent in sporadic breast but not colorectal cancers , 1997, Oncogene.

[74]  M. James,et al.  Erratum: Molecular cytogenetic delineation of a novel critical genomic region in chromosome bands 11q22.3-q23.1 in lymphoproliferative disorders (Proceedings of the National Academy of Sciences of the United States of America (October 15, 1996) 93:21 (11837-11841)) , 1996 .

[75]  H P Koeffler,et al.  TEL/AML-1 dimerizes and is associated with a favorable outcome in childhood acute lymphoblastic leukemia. , 1996, Blood.

[76]  I. Garkavtsev,et al.  Suppression of the novel growth inhibitor p33ING1 promotes neoplastic transformation , 1996, Nature Genetics.

[77]  I. Petersen,et al.  Distinct patterns of chromosomal alterations in high- and low-grade head and neck squamous cell carcinomas. , 1996, Cancer research.

[78]  A. Green,et al.  DELETIONS OF CHROMOSOME 20q AND THE PATHOGENESIS OF MYELOPROLIFERATIVE DISORDERS , 1996, British journal of haematology.

[79]  P. Jones,et al.  Evidence for two tumor suppressor loci associated with proximal chromosome 9p to q and distal chromosome 9q in bladder cancer and the initial screening for GAS1 and PTC mutations. , 1996, Cancer research.

[80]  M. Masu,et al.  Deleted in Colorectal Cancer (DCC) Encodes a Netrin Receptor , 1996, Cell.

[81]  M. James,et al.  Molecular cytogenetic delineation of a novel critical genomic region in chromosome bands 11q22.3-923.1 in lymphoproliferative disorders. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[82]  R. Myers,et al.  Fluorescence in situ hybridization deletion mapping at 4p16.3 in bladder cancer cell lines refines the localisation of the critical interval to 30 kb , 1996, Genes, chromosomes & cancer.

[83]  P. Goodfellow,et al.  Allelotype analysis of esophageal adenocarcinomas: evidence for the involvement of sequences on the long arm of chromosome 4. , 1996, Cancer research.

[84]  C. Croce,et al.  FHIT gene alterations in head and neck squamous cell carcinomas. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[85]  Irene L Andrulis,et al.  MADR2 Maps to 18q21 and Encodes a TGFβ–Regulated MAD–Related Protein That Is Functionally Mutated in Colorectal Carcinoma , 1996, Cell.

[86]  K. Winzer,et al.  A defined chromosome 6q fragment (at D6S310) harbors a putative tumor suppressor gene for breast cancer. , 1996, Oncogene.

[87]  H. Yamamoto,et al.  Inverse association of cell adhesion regulator messenger RNA expression with metastasis in human colorectal cancer. , 1996, Cancer research.

[88]  M. Wigler,et al.  Evaluation of the FHIT gene in colorectal cancers. , 1996, Cancer research.

[89]  R. Lotan,et al.  DPC4, a candidate tumor suppressor gene, is altered infrequently in head and neck squamous cell carcinoma. , 1996, Cancer research.

[90]  Kathleen R. Cho,et al.  DPC4 gene in various tumor types. , 1996, Cancer research.

[91]  J. Downing,et al.  High incidence of TEL/AML1 fusion resulting from a cryptic t(12;21) in childhood B-lineage acute lymphoblastic leukemia in Taiwan. , 1996, Leukemia.

[92]  L. Liotta,et al.  Analysis of 99 microdissected prostate carcinomas reveals a high frequency of allelic loss on chromosome 8p12-21. , 1996, Cancer research.

[93]  R. Greenberg,et al.  Loss of heterozygosity studies indicate that chromosome arm 1p harbors a tumor suppressor gene for renal oncocytomas , 1996, Genes, chromosomes & cancer.

[94]  D. Grandér,et al.  Prognostic importance of p15INK4B and p16INK4 gene inactivation in childhood acute lymphocytic leukemia. , 1996, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[95]  S. Boyle,et al.  Detailed physical and deletion mapping of 8p with isolation of YAC clones from tumour suppressor loci involved in colorectal cancer. , 1996, Oncogene.

[96]  C. Croce,et al.  The FHIT Gene at 3p14.2 Is Abnormal in Lung Cancer , 1996, Cell.

[97]  P. Marynen,et al.  The 12;21 translocation involving TEL and deletion of the other TEL allele: two frequently associated alterations found in childhood acute lymphoblastic leukemia. , 1996, Blood.

[98]  D. Wechsler,et al.  Genomic organization of human MXI1, a putative tumor suppressor gene. , 1996, Genomics.

[99]  I. Petersen,et al.  Evidence for a novel tumor suppressor gene on chromosome 15 associated with progression to a metastatic stage in breast cancer. , 1996, Oncogene.

[100]  M. Knowles,et al.  Deletion mapping implicates two tumor suppressor genes on chromosome 8p in the development of bladder cancer. , 1996, Oncogene.

[101]  R. Maestro,et al.  Chromosome 13q deletion mapping in head and neck squamous cell carcinomas: identification of two distinct regions of preferential loss. , 1996, Cancer research.

[102]  C. Croce,et al.  The FHIT Gene, Spanning the Chromosome 3p14.2 Fragile Site and Renal Carcinoma–Associated t(3;8) Breakpoint, Is Abnormal in Digestive Tract Cancers , 1996, Cell.

[103]  W. Foulkes,et al.  Refinement of two chromosome 11q regions of loss of heterozygosity in ovarian cancer. , 1996, Cancer research.

[104]  Julian Peto,et al.  Identification of the breast cancer susceptibility gene BRCA2 , 1996, Nature.

[105]  Scott E. Kern,et al.  DPC4, A Candidate Tumor Suppressor Gene at Human Chromosome 18q21.1 , 1996, Science.

[106]  A. Marchetti,et al.  Multiple regions of chromosome 6q affected by loss of heterozygosity in primary human breast carcinomas. , 1996, British Journal of Cancer.

[107]  A. Green,et al.  The human CD40 gene lies within chromosome 20q deletions associated with myeloid malignancies , 1996, British journal of haematology.

[108]  J. Sklar,et al.  Loss of heterozygosity at chromosome regions 22q11–12 and 11p15.5 in renal rhabdoid tumors , 1996, Genes, chromosomes & cancer.

[109]  M. Vijver,et al.  E‐cadherin is a tumour/invasion suppressor gene mutated in human lobular breast cancers. , 1995, The EMBO journal.

[110]  S. Shurtleff,et al.  TEL/AML1 fusion resulting from a cryptic t(12;21) is the most common genetic lesion in pediatric ALL and defines a subgroup of patients with an excellent prognosis. , 1995, Leukemia.

[111]  T. Polascik,et al.  Distinct regions of allelic loss on chromosome 4 in human primary bladder carcinoma. , 1995, Cancer research.

[112]  J. Weissenbach,et al.  Loss of the chromosomal region 10q23-25 in prostate cancer. , 1995, Cancer research.

[113]  Patricia A. Elder,et al.  Detailed deletion mapping of chromosome 9q in bladder cancer: evidence for two tumour suppressor loci. , 1995, Oncogene.

[114]  A M Goldstein,et al.  Increased risk of pancreatic cancer in melanoma-prone kindreds with p16INK4 mutations. , 1995, The New England journal of medicine.

[115]  Kathleen R. Cho,et al.  Frequency of homozygous deletion at p16/CDKN2 in primary human tumours , 1995, Nature Genetics.

[116]  D. Forman,et al.  Candidate regions for a testicular cancer susceptibility gene , 1995 .

[117]  W. J. Brammar,et al.  Loss of heterozygosity on the X chromosome in human breast cancer , 1995, Genes, chromosomes & cancer.

[118]  T. Polascik,et al.  Novel suppressor loci on chromosome 14q in primary bladder cancer. , 1995, Cancer research.

[119]  E. Hovig,et al.  Homozygous deletion frequency and expression levels of the CDKN2 gene in human sarcomas--relationship to amplification and mRNA levels of CDK4 and CCND1. , 1995, British Journal of Cancer.

[120]  P. Nowell,et al.  Physical mapping of the minimal region of loss in 5q- chromosome. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[121]  C. Bartram,et al.  Analysis of a family of cyclin-dependent kinase inhibitors: p15/MTS2/INK4B, p16/MTS1/INK4A, and p18 genes in acute lymphoblastic leukemia of childhood. , 1995, Blood.

[122]  L. Sandkuijl,et al.  Homozygotes for CDKN2 (p16) germline mutation in Dutch familial melanoma kindreds , 1995, Nature Genetics.

[123]  D. Le Paslier,et al.  The t(12;21) of acute lymphoblastic leukemia results in a tel-AML1 gene fusion. , 1995, Blood.

[124]  H. Döhner,et al.  Comparative genomic hybridization in chronic B-cell leukemias shows a high incidence of chromosomal gains and losses. , 1995, Blood.

[125]  G. Hampton,et al.  A defined region of loss of heterozygosity at 11q23 in cutaneous malignant melanoma. , 1995, Cancer research.

[126]  D C Ward,et al.  Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[127]  F. Mandelli,et al.  Detection of homozygous deletions of the cyclin-dependent kinase 4 inhibitor (p16) gene in acute lymphoblastic leukemia and association with adverse prognostic features. , 1995, Blood.

[128]  K. Buetow,et al.  Characterization of chromosome 9 in human ovarian neoplasia identifies frequent genetic imbalance on 9q and rare alterations involving 9p, including CDKN2. , 1995, Cancer research.

[129]  S. Shurtleff,et al.  Frequent deletion of p16INK4a/MTS1 and p15INK4b/MTS2 in pediatric acute lymphoblastic leukemia. , 1995, Blood.

[130]  C. Herrington,et al.  Loss of heterozygosity occurs at the D11S29 locus on chromosome 11q23 in invasive cervical carcinoma. , 1995, British Journal of Cancer.

[131]  M. Santibanez-Koref,et al.  Allelic imbalance of chromosome 6q in ovarian tumours. , 1995, British Journal of Cancer.

[132]  J. Zenklusen,et al.  Frequent loss of heterozygosity in human primary squamous cell and colon carcinomas at 7q31.1: evidence for a broad range tumor suppressor gene. , 1995, Cancer research.

[133]  Y. Nakamura,et al.  Isolation of a candidate tumor suppressor gene on chromosome 8p21.3-p22 that is homologous to an extracellular domain of the PDGF receptor beta gene. , 1995, Oncogene.

[134]  J. Sklar,et al.  Correlation of loss of heterozygosity at chromosome 9q with histological subtype in medulloblastomas. , 1995, The American journal of pathology.

[135]  M. Santibanez-Koref,et al.  Proximal 6q, a region showing allele loss in primary breast cancer. , 1995, British Journal of Cancer.

[136]  B. Quesnel,et al.  p16 gene homozygous deletions in acute lymphoblastic leukemia. , 1995, Blood.

[137]  John Calvin Reed,et al.  Tumor suppressor p53 is a direct transcriptional activator of the human bax gene , 1995, Cell.

[138]  F. Sigaux,et al.  Candidate tumor-suppressor genes MTS1 (p16INK4A) and MTS2 (p15INK4B) display frequent homozygous deletions in primary cells from T- but not from B-cell lineage acute lymphoblastic leukemias. , 1994, Blood.

[139]  P. Troncoso,et al.  Loss of heterozygosity in human primary prostate carcinomas: a possible tumor suppressor gene at 7q31.1. , 1994, Cancer research.

[140]  K. Kinzler,et al.  Deletion of p16 and p15 genes in brain tumors. , 1994, Cancer research.

[141]  B. Pedersen,et al.  A factor encoded by 7q31 suppresses expansion of the 7q- clone and delays cytogenetic progression. , 1994, Cancer genetics and cytogenetics.

[142]  O. Olopade,et al.  p16 alterations and deletion mapping of 9p21-p22 in malignant mesothelioma. , 1994, Cancer research.

[143]  Ashutosh Kumar Singh,et al.  Rarity of somatic and germline mutations of the cyclin-dependent kinase 4 inhibitor gene, CDK4I, in melanoma. , 1994, Cancer research.

[144]  S. Seal,et al.  Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13. , 1994, Science.

[145]  W. Clark,et al.  Germline p16 mutations in familial melanoma , 1994, Nature Genetics.

[146]  G. Hampton,et al.  Loss of heterozygosity in sporadic human breast carcinoma: a common region between 11q22 and 11q23.3. , 1994, Cancer research.

[147]  R. Hruban,et al.  Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma , 1994, Nature Genetics.

[148]  H. Sasaki,et al.  Allelotype of endometrial carcinoma. , 1994, Cancer research.

[149]  R. Chaganti,et al.  Allelotype analysis of cervical carcinoma. , 1994, Cancer research.

[150]  G. Chenevix-Trench,et al.  Fine genetic mapping of the gene for nevoid basal cell carcinoma syndrome. , 1994, Genomics.

[151]  G. Hampton,et al.  Loss of heterozygosity in cervical carcinoma: subchromosomal localization of a putative tumor-suppressor gene to chromosome 11q22-q24. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[152]  A. Sancar,et al.  Formation of a ternary complex by human XPA, ERCC1, and ERCC4(XPF) excision repair proteins. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[153]  A. Munnich,et al.  A gene for hereditary multiple exostoses maps to chromosome 19p. , 1994, Human molecular genetics.

[154]  A. Goldstein,et al.  Localization of the gene for the nevoid basal cell carcinoma syndrome. , 1994, American journal of human genetics.

[155]  Todd R. Golub,et al.  Fusion of PDGF receptor β to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation , 1994, Cell.

[156]  M. Skolnick,et al.  A cell cycle regulator potentially involved in genesis of many tumor types. , 1994, Science.

[157]  J Piper,et al.  Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[158]  Olivier Delattre,et al.  Evidence for the complete inactivation of the NF2 gene in the majority of sporadic meningiomas , 1994, Nature Genetics.

[159]  G. Hannon,et al.  A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4 , 1993, Nature.

[160]  B. Johansson,et al.  Cytogenetic deletion maps of hematologic neoplasms: Circumstantial evidence for tumor suppressor Loci , 1993, Genes, chromosomes & cancer.

[161]  S. Coons,et al.  Expression of the tumor suppressor gene DCC in human gliomas. , 1993, Cancer research.

[162]  K Offit,et al.  6q deletions define distinct clinico-pathologic subsets of non-Hodgkin's lymphoma. , 1993, Blood.

[163]  S. Korsmeyer,et al.  Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death , 1993, Cell.

[164]  M. Carcangiu,et al.  Allelic loss in ovarian cancer , 1993, International journal of cancer.

[165]  D. Grignon,et al.  Frequent loss of expression and loss of heterozygosity of the putative tumor suppressor gene DCC in prostatic carcinomas. , 1993, Cancer research.

[166]  E. Friedberg,et al.  Characterization of a complex chromosomal rearrangement maps the locus for In vitro complementation of xeroderma pigmentosum group D to human chromosome band 19q 13 , 1992, Genes, chromosomes & cancer.

[167]  D. Pinkel,et al.  Comparative Genomic Hybridization for Molecular Cytogenetic Analysis of Solid Tumors , 2022 .

[168]  Shibo Li,et al.  Frequent loss of heterozygosity on chromosomes Xp and 13q in human ovarian cancer , 1992, International journal of cancer.

[169]  B. Horsthemke.  Genetics and cytogenetics of retinoblastoma. , 1992, Cancer genetics and cytogenetics.

[170]  P. Friedman,et al.  Wild-type p53 activates transcription in vitro , 1992, Nature.

[171]  S. Hirohashi,et al.  Frequent loss of heterozygosity at the DCC locus in gastric cancer. , 1992, Cancer research.

[172]  R. Weinel,et al.  Frequent loss of expression of the potential tumor suppressor gene DCC in ductal pancreatic adenocarcinoma. , 1992, Cancer research.

[173]  S. Squires,et al.  The XPD complementation group. Insights into xeroderma pigmentosum, Cockayne's syndrome and trichothiodystrophy. , 1992, Mutation research.

[174]  M. Ohki,et al.  t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[175]  B. Vogelstein,et al.  p53 mutations in human cancers. , 1991, Science.

[176]  P. Devilee,et al.  Somatic genetic changes on chromosome 18 in breast carcinomas: is the DCC gene involved? , 1991, Oncogene.

[177]  C. Marshall.  Tumor suppressor genes , 1991, Cell.

[178]  P. O’Connell,et al.  The GAP-related domain of the neurofibromatosis type 1 gene product interacts with ras p21 , 1990, Cell.

[179]  A. Yasui,et al.  Analysis of a human DNA excision repair gene involved in group A xeroderma pigmentosum and containing a zinc-finger domain , 1990, Nature.

[180]  Kathleen R. Cho,et al.  Identification of a chromosome 18q gene that is altered in colorectal cancers. , 1990, Science.

[181]  S. Hinrichs,et al.  Structural evidence for the authenticity of the human retinoblastoma gene. , 1987, Science.

[182]  Stephen H. Friend,et al.  A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma , 1986, Nature.

[183]  M. Isobe,et al.  Localization of gene for human p53 tumour antigen to band 17p13 , 1986, Nature.

[184]  R. Larson,et al.  Clinical and cytogenetic correlations in 63 patients with therapy-related myelodysplastic syndromes and acute nonlymphocytic leukemia: further evidence for characteristic abnormalities of chromosomes no. 5 and 7. , 1986, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[185]  A. Knudson.  Mutation and cancer: statistical study of retinoblastoma. , 1971, Proceedings of the National Academy of Sciences of the United States of America.

[186]  Christophe Béroud,et al.  Software and database for the analysis of mutations in the VHL gene , 1998, Nucleic Acids Res..

[187]  A. Bale.  The nevoid basal cell carcinoma syndrome: genetics and mechanism of carcinogenesis. , 1997, Cancer investigation.

[188]  Darryl Shibata,et al.  Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis , 1997, Nature Genetics.

[189]  William D. Foulkes,et al.  The CDKN2A (p16) Gene and Human Cancer , 1997, Molecular medicine.

[190]  Y. Shiloh,et al.  The ATM gene and protein: possible roles in genome surveillance, checkpoint controls and cellular defence against oxidative stress. , 1997, Cancer surveys.

[191]  J. Brieger,et al.  The von Hippel-Lindau tumor suppressor gene. A rare and intriguing disease opening new insight into basic mechanisms of carcinogenesis. , 1997, Cancer genetics and cytogenetics.

[192]  Thierry Soussi,et al.  APC gene: database of germline and somatic mutations in human tumors and cell lines , 1996, Nucleic Acids Res..

[193]  Lei Li,et al.  Characterization of molecular defects in xeroderma pigmentosum group C , 1993, Nature Genetics.

[194]  J. Hancock,et al.  DCC tumor suppressor gene is inactivated in hematologic malignancies showing monosomy 18. , 1993, Blood.

[195]  Weinberg Ra.  The retinoblastoma gene and gene product. , 1992 .

[196]  R. Weinberg.  The retinoblastoma gene and gene product. , 1992, Cancer surveys.